INTRAVITREAL

作品数：143被引量：352H指数：8
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相关领域：医药卫生更多>>
相关作者：张明洲刘嫣江晓丹吕会斌李学民更多>>
相关机构：哈尔滨医科大学附属第二医院温州医科大学第三军医大学大坪医院中山大学更多>>
相关期刊：《World Journal of Experimental Medicine》《Acta Pharmacologica Sinica》《Journal of Biomedical Science and Engineering》《World Journal of Clinical Cases》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划以色列科学基金上海市浦江人才计划项目更多>>
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Effect of simultaneous intravitreal ranibizumab and extended-release dexamethasone injection on patients with naïve versus refractory retinal vein occlusion macular edema:a prospective,multicenter,and interventional open-label study
《International Journal of Ophthalmology(English edition)》2025年第5期860-867,共8页Yao-Yao Sun Jie Meng Shan-Shan Li Qin Xiao Tian-Zi Zhang Heng Miao Ming-Wei Zhao Hui-Jun Qi 
Supported by the National Nature Science Foundation of China(No.82301211);Beijing Natural Science Foundation(No.J230028).
AIM:To evaluate the efficacy and safety of concurrent intravitreal ranibizumab(IVR)and extended-release dexamethasone injections(Dex-I)in naïve and refractory patients with retinal vein occlusion macular edema(RVO-ME)...
关键词：retinal vein occlusion macular edema prospective clinical trial anti-vascular endothelial growth factor dexamethasone implant 
Dexamethasone intravitreal implant monotherapy in naive patients with macular edema secondary to retinal vein occlusion:long term follow-up retrospective cohort study
《International Journal of Ophthalmology(English edition)》2025年第5期876-882,共7页Gamze Karataş AkınÇakır Tahsin Uzundede Öznur Aday Ahmet MelihÖzoğuz Mehmet Egemen Karataş AslıKırmacıKabakcı 
AIM:To investigate the efficacy and safety of repeated dexamethasone implants with real-life data in eyes with naive retinal vein occlusion(RVO)with macular edema(ME)at a minimum of 60mo follow-up.METHODS:In this retr...
关键词：DEXAMETHASONE intravitreal naïve retinal vein occlusion macular edema 
Intravitreal low-dose triamcinolone acetonide for nonarteritic anterior ischemic optic neuropathy
《International Journal of Ophthalmology(English edition)》2025年第4期663-671,共9页Zi-Jia Liu Xian Xu Ya-Nan Lyu Dong-Li Li Hao Zhou Yuan-Yuan Gong 
Supported by the National Key R&D Program of China(No.2016YFC0904800,No.2019YFC0840607);the National Science and Technology Major Project of China(No.2017ZX09304010);the Clinical Research Innovation Plan of Shanghai General Hospital(No.CTCCR-2018BP04).
AIM:To evaluate the efficacy and safety of intravitreal low-dose(1 mg)triamcinolone acetonide(TA)in Chinese acute nonarteritic anterior ischemic optic neuropathy(NAION)patients.METHODS:Twenty-eight eyes of 28 patients...
关键词：nonarteritic anterior ischemic optic neuropathy triamcinolone acetonide intravitreal injections visual field visual acuity 
Phacoemulsification surgery in patients with diabetic macular edema:should intravitreal anti-VEGF therapy be performed before or simultaneously with surgery?
《International Journal of Ophthalmology(English edition)》2025年第4期637-641,共5页Yusuf Ziya Güven Mehmed Uğur Işık Serdar Ilgüy Zübeyir Yozgat 
AIM:To investigate the optimal anti-vascular endothelial growth factor(VEGF)treatment time in patients with diabetic macular edema(DME)scheduled for cataract surgery.METHODS:The study was designed to include 4 groups....
关键词：cataract surgery diabetic macular edema timing of anti-vascular endothelial growth factor therapy 
Renal dysfunction associated with clinical response to intravitreal conbercept therapy for diabetic macular edema
《International Journal of Ophthalmology(English edition)》2025年第3期454-461,共8页Wei Wu Hui-Dong Liu Xue Xiao Ya-Xin Wang Song-Fu Feng Jia-Qi Liu Yong-Gang Yuan Xiao-He Lu 
Supported by Basic and Applied Basic Research Project of Guangzhou Science and Technology Plan(No.202201020008,No.2023A03J0584).
AIM:To investigate the impact of renal dysfunction on clinical response to intravitreal conbercept injection(IVC)for diabetic macular edema(DME).METHODS:This retrospective study included a total of 100 eyes from 100 p...
关键词：conbercept diabetic macular edema renal dysfunction 
Intravitreal therapy for the management of diabetic retinopathy:A concise review
《World Journal of Experimental Medicine》2024年第4期104-119,共16页Atul Arora Arvind K Morya Parul C Gupta Nitin K Menia Prateek Nishant Vishali Gupta 
Diabetic retinopathy(DR)is a serious microvascular complication of diabetes mellitus and may result in irreversible visual loss.Laser treatment has been the gold standard treatment for diabetic macular edema and proli...
关键词：Diabetic retinopathy Intravitreal therapy Anti-vascular endothelial growth factor Macular edema Proliferative diabetic-retinopathy 
Comparison of efficacy and safety of intravitreal ranibizumab and conbercept before vitrectomy in Chinese proliferative diabetic retinopathy patients:a prospective randomized controlled trial
《Eye and Vision》2024年第6期33-40,共8页Siying Li Lili Guo Pingping Zhou Jiyang Tang Zongyi Wang Linqi Zhang Mingwei Zhao Jinfeng Qu 
funded by Capital Clinical Diagnosis and Treatment Technology Research and Demonstration Application Project of China(Grant No.Z191100006619029);National Key R&D Program of China(Grant No.2020YFC2008200).
Background:To compare the efficacy and safety of preoperative intravitreal injections of ranibizumab and conbercept in Chinese proliferative diabetic retinopathy(PDR)patients.Methods:This prospective randomized contro...
关键词：Proliferative diabetic retinopathy ANTI-VEGF RANIBIZUMAB Conbercept Preoperative intravitreal injections Diabetic vitrectomy Efficacy Safety 
Optical Coherence Tomography (OCT) Feature Identifying Niche for Dexamethasone (FIND) Intravitreal Implant in the Treatment of Anti-VEGF Slow Responders with Diabetic Macular Edema
《Open Journal of Ophthalmology》2024年第4期398-404,共7页Ram Peddada Joshua C. Hollingsworth David Redden Eric Marin 
This paper raises the question if intravitreal dexamethasone implant deserves to be utilized more effectively in a select subset of eyes with diabetic macular edema (DME). If so, what is the OCT morphology of such eye...
关键词：Diabetic Macular Edema Dexamethasone Intravitreal Implant ANTI-VEGF FIND OCT Morphology 
Intravitreal long-term sustained ranibizumab delivery using injectable microgel-embedded hydrogel
《Asian Journal of Pharmaceutical Sciences》2024年第5期126-138,共13页Simin Lee Jun Young Park Hye Kyoung Hong Joo Young Son Byungwook Kim Jae Yong Chung Se Joon Woo Ki Dong Park 
This study was supported by a grant(2019R1A6A1A11051471)from Priority Research Centers Program which was funded by the National Research Foundation of Korea(NRF);the Bio&Medical Technology Development Program(2018M3A9B5021319)which was funded by the Ministry of Science and ICT,South Korea(MSIT);a grant from Seoul National University Bundang Hospital(14-2023-0001);a grant from Korea Medical Device Development Fund by the Korea government(RS-2020-KD000033);a grant from the Alchemist Project of Korea Evaluation Institute of Industrial Technology(KEIT 20018560,NTIS 1415184668)which was funded by the Ministry of Trade,Industry&Energy.
Retinal vascular disease is the leading cause of visual impairment.Although intravitreal drug injections are the most suitable approach for addressing retinal disorders,existing clinical treatments necessitate repeate...
关键词：Age-related macular degeneration RANIBIZUMAB Microgel-embedded hydrogel Long-term drug delivery Pharmacokinetics Biodegradation 
Vascular endothelial growth factor/connective tissue growth factor and proteomic analysis of aqueous humor after intravitreal conbercept for proliferative diabetes retinopathy
《International Journal of Ophthalmology(English edition)》2024年第10期1816-1827,共12页Hou-Shuo Li Xiao Lyu Ao Rong Yan-Long Bi Wei Xu Hong-Ping Cui 
AIM:To investigate the role of connective tissue growth factor(CTGF)and vascular endothelial growth factor(VEGF)in the protein profile of the aqueous humor in patients with proliferative diabetic retinopathy(PDR)follo...
关键词：proliferative diabetic retinopathy conbercept vascular endothelial growth factor connective tissue growth factor PROTEOMICS 
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