TETRAPEPTIDE

作品数:13被引量:3H指数:1
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相关领域:理学生物学更多>>
相关作者:陈欣陈惠宾王耀林子敬更多>>
相关机构:中国科学技术大学陕西慧康生物科技有限责任公司更多>>
相关期刊:《Chemical Research in Chinese Universities》《Transactions of Tianjin University》《Chinese Journal of Chemistry》《Food Science and Human Wellness》更多>>
相关基金:国家自然科学基金中国博士后科学基金更多>>
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Colorimetric Recognition of 3,4-Dihydroxy-D,L-phenylalanine with Tetrapeptide-modified Copper Nanoparticles as Chiral Nanozymes
《Chemical Research in Chinese Universities》2023年第6期1092-1099,共8页TIAN Lin CHENG Cheng ZHAO Zhenwen LIU Wei QI Li 
supported by the National Natural Science Foundation of China(No.22274159)。
The construct of artificial nanocatalyts by simulating natural enzymes and thereby bringing new properties for practical applications is still a challenging task to date.In this study,chiral tetrapeptide(L-phenylalani...
关键词:Chiral nanozyme Copper nanoparticle 3 4-Dihydroxy-D L-phenylalanine(D L-DOPA) ENANTIOSELECTIVITY Tetrapeptide ligand 
Tetrapeptide self-assembled multicolor fluorescent nanoparticles for bioimaging applications被引量:1
《Chinese Chemical Letters》2023年第6期417-420,共4页Yuerong Wang Yang Lei Jiaye Wang Hui Yang Leming Sun 
supported by the National Natural Science Foundation of China(No.31900984);the Fundamental Research Funds for the Central Universities(No.D5000210899);Innovation and Entrepreneurship Fund from the Student Affairs Department of the Party Committee of Northwestern Polytechnic University(No.2021-CXCY-019)。
The biocompatibility and biodegradability of peptide self-assembled materials makes them suitable for many biological applications,such as targeted drug delivery,bioimaging,and tracking of therapeutic agents.According...
关键词:SELF-ASSEMBLY TETRAPEPTIDE MULTICOLOR Fluorescent nanoparticles BIOIMAGING 
Identifi cation and characterization of a novel tetrapeptide from enzymatic hydrolysates of Baijiu byproduct
《Food Science and Human Wellness》2022年第6期1641-1649,共9页Qiang Wu Changqing Zhong Guirong Zeng Xu Zhang Liping Xiang Chang Wan Yougui Yu 
sponsored by the Outstanding Youth Project of Hunan Education Department(19B505);Changsha City Science and Technology Plan Project(kq2004113);the 2020 Natural Science Foundation of Hunan Province of China(2020JJ8061);the 2020 Science and Technology Innovation Project of Hunan Province of China(2020SK50921);the Undergraduate Inquiry Learning and Innovative Experimental Project of Hunan Education Department(2019[100]-1886)。
In order to prepare angiotensin I-converting enzyme(ACE)inhibitory peptides,distilled spent grains of Chinese strong-flavor Baijiu were hydrolyzed by alcalase followed by papain under optimized conditions.A superior A...
关键词:Baijiu Distilled spent grain ACE inhibitory peptide Inhibition mechanism 
A novel mitochondria-targeting tetrapeptide for subcellular delivery of nanoparticles被引量:1
《Chinese Chemical Letters》2019年第7期1435-1439,共5页Yanhui Sun Aiyan Zhan Shuang Zhou Xiao Kuang Hongyan Shen Hongzhuo Liu Youjun Xu 
financially supported by the National Natural Science Foundation of China (No. 81473162);the Program for Liaoning Excellent Talents in University;the Young and Middleaged Career Development Planning of Shenyang Pharmaceutical University
Mitochondrial dysfunction is associated with the emergence of several neurological and cardiovascular diseases. Hence, mitochondria-targeting delivery strategies are highly significant and critically needed. In this s...
关键词:MITOCHONDRIAL targeting Peptide SS-31 Toxicity NANOPARTICLES ZEBRAFISH 
一种Tetrapeptide-21的合成
《现代医学与健康研究电子杂志》2018年第3期197-198,共2页李晨 李乾 陈科 郭添 杨小琳 赵金礼 
Tetrapeptide-21是一种四肽酶,其序列为Gly-Glu-Lys-Gly,存在于一些人的细胞外基质蛋白质中,具有显著的抗皱抗衰老潜能。本文介绍一种多肽固相合成方案,全程在无水环境中,以2-CTC Resin树脂为原料进行逐个Fmoc保护的氨基酸缩合连接。合...
关键词:Tetrapeptide-21 抗皱 抗衰老 多肽固相合成 
Improvement of Stability and Anticancer Activity of ChlorambuciI-Tetrapeptide Conjugate Vesicles
《Chinese Journal of Chemistry》2016年第6期609-616,共8页Wei Zhang Wenjun Zhu Ruiyu He Shuo Fang Yemin Zhang Chen Yao Muhammad Ismail Xinsong Li 
Chlorambucil is a classic nitrogen mustard drug that has been used in the treatment of cancers. It may induce neutropenia, thrombocytopenia and other side effects because of its short lifetime and off-target effect. I...
关键词:chlorambucil-tetrapeptide conjugate SELF-ASSEMBLY vesicles anticancer activity 
Novel Chemical Strategy for the Synthesis of RGDCySS Tetrapeptide
《Chemical Research in Chinese Universities》2014年第1期103-107,共5页XU Baofeng YANG Sen ZHU Jinming MA Yudan ZHAO Gang GUO Yi XU Li 
Supported by the National Natural Science Foundation of China(No.81271697), the Science Foundation of Changchun City, China(No.09SF02), the China Postdoctoral Science Foundation(No.20100481048), the Specialized Research Fund for the Doctoral Program of Higher Education of China(No.20100061120077) and the Social Development Project of Science and Tech- nology Department of Jilin Province, China(Nos.20106031, 20120967, YYZX2012).
A new route was described to synthesize Arg-Gly-Asp-X(RGDX,X=amino acid) tetrapeptide.To better understand the method,the tetrapeptide Arg-Gly-Asp-CySS(RGDCySS) was chosen as a model target for X.First,GDCySS was ...
关键词:Arg-Gly-Asp(RGD) Arg-Gly-Asp-X(RGDX) Peptide synthesis Arg-Gly-Asp-CySS(RGDCySS) Chemical method N-Carboxy-a-amino acid anhydride(NCA) 
Gas Phase Conformations of Tetrapeptide Glycine-Phenylalanine- Glycine-Glycine
《Chinese Journal of Chemical Physics》2012年第1期77-85,I0004,共10页陈惠宾 王耀 陈欣 林子敬 
Systematic search of the potential energy surface of tetrapeptide glycine-phenylalanine- glycine-glycine (GFGG) in gas phase is conducted by a combination of PM3, HF and BHandHLYP methods. The conformational search ...
关键词:Potential energy surface Conformational stability Hydrogen bond Entropy effect Secondary structure 
Overexpression of the angiogenic tetrapeptide AcSDKP and the prolyl oligopeptidase(POP) is a common feature of cancer
《生物物理学报》2009年第S1期32-33,共2页Jérme Bignon Alexia Pinault Joanna Wdzieczak-Bakala 
Prolyl oligopeptidase (POP) is a cytosolic enzyme involved in the metabolism of many peptide hormones and neuropeptides (1). It was recently reported that POP is responsible
关键词:ACSDKP Overexpression of the angiogenic tetrapeptide AcSDKP and the prolyl oligopeptidase is a common feature of cancer POP 
Synthesis of Protected Tetrapeptide, N-o-Ns-N(Me)-Val-N(Me)-Val-N(Me)-Val-N(Me)-Phe-O^tBu
《Transactions of Tianjin University》2006年第5期364-368,共5页陈宏亮 冯亚青 孟舒献 刘新刚 
The protected tetrapeptide, N-o-Ns-N ( Me ) -Val-N ( Me ) -Val-N ( Me ) -Val- N ( Me ) -Phe- OtBu, was prepared from L-valine and L-phenylalanine. Ted-butyl acetate and HClO4 were used to protect carbonyl grou...
关键词:synthesis TETRAPEPTIDE L-VALINE L-PHENYLALANINE 
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