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作品数:32被引量:56H指数:3
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相关领域:经济管理更多>>
相关作者:王岩更多>>
相关机构:北京第二外国语大学河北科技大学上海海事大学更多>>
相关期刊:《Science Bulletin》《China & World Economy》《Molecular Plant》《China Today》更多>>
相关基金:国家自然科学基金更多>>
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Complexation of CcmB with CcmACD safeguards heme translocation for cytochrome c maturation
《mLife》2025年第1期29-44,共16页Yuanyou Xu Wei Wang Qianrou Zhang Sirui Han Jiahao Wang Shihua Wu Haichun Gao 
supported by the National Natural Science Foundation of China(31930003 and 41976087);the National Key R&D Program of China(2018YFA0901300).
Cytochrome c maturation(CCM),a posttranslational modification involving covalent attachment of heme to polypeptides(apocyt c),is essential for the activity and cellular function of cytochromes c.Here,we identify and s...
关键词:CcmABCD cytochrome c cytochrome c biosynthesis HEME heme translocation 
Adhere to the Correct View of Human Rights,and Strengthen Judicial Safeguards for Human Rights Law Enforcement
《The Journal of Human Rights》2024年第6期1259-1264,共6页ZHANG Wenxian 
The resolution adopted at the Third Plenary Session of the 20th CPC Central Committee set the objective of advancing whole-process people’s democracy, including promoting socialist rule of law with Chinese characteri...
关键词:LAW thereby arrangement 
Enhance Judicial Systems and Mechanisms for Impartial Law Enforcement and Strengthen Judicial Safeguards for Human Rights
《The Journal of Human Rights》2024年第6期1268-1272,共5页LI Xiao 
The Resolution of the Central Committee of the Communist Party of China on Further Deepening Reform Comprehensively to Advance Chinese Modernization(hereinafter referred to as the“Resolution”)was reviewed and adopte...
关键词:Deep SESSION Resolution 
ILF3 safeguards telomeres from aberrant homologous recombination as a telomeric R-loop reader
《Protein & Cell》2024年第7期493-511,共19页Chuanle Wang Yan Huang Yue Yang Ruofei Li Yingying Li Hongxin Qiu Jiali Wu Guang Shi Wenbin Ma Zhou Songyang 
National Natural Science Foundation(Grant Nos.82271598,81871109,82071587,31930058,32330023 and 32170757);National Key Research and Development Program of China(2018YFA0107003);Guang Dong Basic and Applied Basic Research Foundation(2020A1515010462).
Telomeres are specialized structures at the ends of linear chromosomes that protect genome stability.The telomeric repeat-containing RNA(TERRA)that is transcribed from subtelomeric regions can invade into double-stran...
关键词:ILF3 RNA:DNA hybrids telomeric R-loops homologous recombination telomeric DNA damage responses 
Ptip safeguards the epigenetic control of skeletal stem cell quiescence and potency in skeletogenesis被引量:1
《Science Bulletin》2024年第13期2099-2113,共15页Jianfei Liang Jing Wang Bingdong Sui Yibo Tong Jihua Chai Qin Zhou Chenxi Zheng Hao Wang Liang Kong Haojian Zhang Yi Bai 
supported by the National Key Research and Development Program of China(2022YFA0103200);the National Natural Science Foundation of China(82325003,82230007,82200188,82270956 and 82171568);the National Defense Biotechnology Outstanding Young Talents Fund(01-SWKJYCJJ24);Shaanxi Province Innovation Capability Support Program Scientific and Technological Innovation Team(2023-CX-TD-69).
Stem cells remain in a quiescent state for long-term maintenance and preservation of potency;this process requires fine-tuning regulatory mechanisms.In this study,we identified the epigenetic landscape along the devel...
关键词:Skeletal stem cells Bone development Epigenetics Ptip GLYCOLYSIS 
Reconciling host-microbiota metabolic incompatibility safeguards male fertility
《hLife》2024年第6期284-295,共12页Qing Shang Zhuoyang Li Na Yin Min Peng 
This research was supported by Tsinghua University Initiative Scientific Research Program (to M.P.) and funds from Tsinghua-Peking Center for Life Sciences and Institute forImmunology at Tsinghua University (to M.P.).
The symbiotic relationship between the host and microbiota is widely acknowledged as mutually beneficial.However,due to significant differences in metabolic substrates and products between prokaryotic bacteria and mam...
关键词:ACETATE acetyl-CoA synthetase short-chain family member 1(ACSS1) acetyl-CoA synthetase short-chain family member 2(ACSS2) ACIDOSIS male infertility MICROBIOTA nicotinamide adenine dinucleotide(NAD+) BETAINE 
The Three Principles of Institutional Safeguards for Women's Participation in Legislation in China
《The Journal of Human Rights》2024年第2期325-346,共22页刘睿 JIANG Yu(Translated) 
a phased project of the “Research on the Principles of Argumentation of Ratio Legis (Reasons) in Local Legislation” (Project Approval Number 2023EFX002);a Youth Project of Shanghai Philosophy and Social Science Planning in 2023。
The participation of women in legislation is an important aspect and means of safeguarding women’s rights.Feminist theory,based on criticism of both the“citizenship identity theory as rights”and the“citizenship id...
关键词:citizenship identity theory FEMINISM women’s rights participation in legislation SUBJECTIVITY 
Digital identity,privacy security,and their legal safeguards in the Metaverse被引量:1
《Security and Safety》2023年第2期72-85,共14页Hong Wu Wenxiang Zhang 
supported by the 2021 National Social Sciencetitled“Research on the Legal Risks and Prevention of China’s Social Media Platforms Operating in the United States”(21BXW040)
The Metaverse is the digitization of the real world,supported by big data,AI,5G,cloud computing,blockchain,encryption algorithm,perception technology,digital twin,virtual engine,and other technologies that interact wi...
关键词:Metaverse AVATAR Digital identity Privacy security Privacy data Identity authentication 
Oxidative phosphorylation safeguards pluripotency via UDP-N-acetylglucosamine被引量:1
《Protein & Cell》2023年第5期376-381,共6页Jiani Cao Meng Li Kun Liu Xingxing Shi Ning Sui Yuchen Yao Xiaojing Wang Shiyu Li Yuchang Tian Shaojing Tan Qian Zhao Liang Wang Xiahua Chai Lin Zhang Chong Liu Xing Li Zhijie Chang Dong Li Tongbiao Zhao 
We thank Dr Masaru Okabe at Osaka University Japan for providing the B6D2-Tg(CAG/Su9-DsRed2,Acr3-EGFP)RBGS002Osb mice(mito-red);the National Institute for Basic Biology Japan for providing the B6.Cg-Tg(CAG-GFP/LC3)53Nmz/NmzRbrc mice.;the National Key R&D Program of China 2018YFA0108402;the Strategic Priority Research Program of the Chinese Academy of Sciences XDA16030302;the Strategic Collaborative Research Program of the Ferring Institute of Reproductive Medicine Grant No.33,and the National Natural Science Foundation of China Program(31720103907,31570995,31621004),to T.Z.and(31400831)to J.C.The raw data FASTQ files for the RNA sequencing data are deposited in NCBI GEO,GEO:GSE140712(Fig.1D,1E and S4)and ScienceDB,China National Standard GB/T 7714-2015(Fig.S8A,S8F and S8G);The metabolomic data files are deposited in ScienceDB,China National Standard GB/T 7714-2015.
Dear Editor,Embryonic stem cells(ESCs)have been assumed to possess immature mitochondria and to favor anaerobic glycolysis over oxidative phosphorylation(OXPHOS)for energy production.This proposition is largely based ...
关键词:KONDO PHOSPHORYLATION raised 
Cortisol safeguards oogenesis by promoting follicular cell survival被引量:3
《Science China(Life Sciences)》2022年第8期1563-1577,共15页Hesheng Xiao Zhen Xu Xi Zhu Jingrong Wang Qiaoyuan Zheng Qingqing Zhang Chunmei Xu Wenjing Tao Deshou Wang 
supported by the National Key Research and Development Program of China (2018YFD0900202);the National Natural Science Foundation of China (31972778, 31861123001, 31630082, 31872556);the Chongqing Science and Technology Commission (cstc2018jscx-mszd0380, cstc2018jcyj AX0283);Yunnan Science and Technology project (2018IB019)。
The role of glucocorticoids in oogenesis remains to be elucidated. cyp11c1 encodes the key enzyme involved in the synthesis of cortisol, the major glucocorticoid in teleosts. In our previous study, we mutated cyp11c1 ...
关键词:OOGENESIS CORTISOL cyp11c1 Nile tilapia CRISPR/Cas9 
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