POLYPEPTIDES

作品数：76被引量：162H指数：6
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相关作者：刘永强王颖王丽娟王丽娟郭颖洁更多>>
相关机构：广东领秀首美生物科技有限公司长春中医学院白求恩医科大学青岛大学更多>>
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  • 期刊=Neural Regeneration Researchx
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Achyranthes bidentata polypeptides prevent apoptosis by inhibiting the glutamate current in cultured hippocampal neurons被引量：7
《Neural Regeneration Research》2020年第6期1086-1093,共8页Rong-Lu Pan Wen-Qing Hu Jie Pan Li Huang Cheng-Cheng Luan Hong-Mei Shen 
supported by the National Natural Science Foundation of China,No.81073079(to HMS);the Natural Science Foundation of the Jiangsu Higher Education Institute of China,No.18KJA180009(to HMS);the Science Foundation of Nantong City of China,No.MS12018043(to HMS)
Glutamate-induced excitotoxicity plays a critical role in the neurological impairment caused by middle cerebral artery occlusion.Achyranthes bidentata polypeptides have been shown to protect against neurological funct...
关键词：Achyranthes bidentata POLYPEPTIDES APOPTOSIS caspase-3 EXCITOTOXICITY GLUTAMATE receptors MITOCHONDRIAL dysfunction MITOCHONDRIAL membrane potential neuroprotection reactive oxygen species STAUROSPORINE 
Achyranthes bidentata polypeptide protects dopaminergic neurons from apoptosis induced by rotenone and 6-hydroxydopamine
《Neural Regeneration Research》2018年第11期1981-1987,共7页Su Peng Li Xu Jin-Yu Ma Xiao-Song Gu Cheng Sun 
supported by the National Natural Science Foundation of China,No.81471037,81770841;a grant from the Basic Research of Jiangsu Education Department of China,No.14KJA180006;a grant from the Six Talent Summit Project of Jiangsu Province of China,No.SWYY-051;a grant from the Priority Academic Program Development of Jiangsu Higher Education Institutions of China
It has been well documented that Achyranthes bidentata polypeptides（ABPPs） are potent neuroprotective agents in several types of neurons. However, whether ABPPs protect dopaminergic neurons from apoptosis induced by...
关键词：nerve regeneration Achyranthes bidentata polypeptides neuroprotection cell apoptosis NEUROTOXIN mitochondrial dysfunction cell viability Bcl-2/Bax neural regeneration 
The Achyranthes bidentata polypeptide k fraction enhances neuronal growth in vitro and promotes peripheral nerve regeneration after crush injury in vivo被引量：6
《Neural Regeneration Research》2014年第24期2142-2150,共9页Qiong Cheng Chunyi Jiang Caiping Wang Shu Yu Qi Zhang Xiaosong Gu Fei Ding 
supported by a grant from National Key Basic Research Program of China(973 Program),No.2014CB542202;a grant from Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)in China
We have previously shown that Achyranthes bidentata polypeptides （ABPP）, isolated from Achyranthes bidentata Blume （a medicinal herb）, exhibit neurotrophic and neuroprotective effects on the nervous system. To ide...
关键词：nerve regeneration Achyranthes bidentata polypeptides neuroactive component dorsal root ganglion neurite outgrowth crush injury sciatic nerve peripheral nerve regeneration neural regeneration 
Protective effects of Achyranthes bidentata polypeptides on retinal ganglion cells post-optic nerve crush in rats
《Neural Regeneration Research》2011年第15期1164-1168,共5页Nan Hu Qi Zhao Fangling Zhang Junfang Zhang Xiaosong Gu 
the Priority Academic Program Development of Jiangsu Higher Education Institutions (PADA)
Achyranthes bidentata polypeptides（ABPP） have been reported to inhibit apoptosis of retinal ganglion cells（RGCs）.The present study investigated the protective effects of ABPP on RGCs in a rat model of optic nerve ...
关键词：Achyranthes bidentata polypeptides optic nerve crush retinal ganglion cells growth associated protein 43 neural regeneration 
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