POLYPEPTIDES

作品数:76被引量:162H指数:6
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相关领域:生物学更多>>
相关作者:刘永强王颖王丽娟王丽娟郭颖洁更多>>
相关机构:广东领秀首美生物科技有限公司长春中医学院白求恩医科大学青岛大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划安徽省自然科学基金广东省自然科学基金更多>>
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Erratum to:Toxic aldehyde-scavenging polypeptides mitigate secondary injury after spinal cord injury(vol 66,issue 7,page 2931,2023)
《Science China Materials》2024年第10期3426-3426,共1页Yixuan Liu Feng Lin Tianhui Zhang Cheng Wu Wanguo Liu Hao Wang Chunsheng Xiao Xuesi Chen 
In the version of the article originally published in the volume 66,issue 7,2023 of Sci China Mater(pages 2925–2937,https://doi.org/10.1007/s40843-022-2409-4),the images reported in Fig.2d showing the resulting cell ...
关键词:injury correction AFTER 
Gadoxetic acid-enhanced magnetic resonance imaging in the assessment of hepatic sinusoidal obstruction syndrome in a mouse model
《World Journal of Hepatology》2024年第8期1167-1176,共10页Yuan-Yuan Chen Li Yang Jun Li Sheng-Xiang Rao Ying Ding Meng-Su Zeng 
the National Science Foundation for Young Scientists of China,No.81701682.
BACKGROUND Neoadjuvant chemotherapy can cause hepatic sinusoidal obstruction syndrome(SOS)in patients with colorectal cancer liver metastases and increases posto-perative morbidity and mortality.AIM To evaluate T1 map...
关键词:T_(1)mapping Gadoxetic acid Sinusoidal obstruction syndrome Organic anion transporter polypeptides Magnetic resonance imaging 
Reduced Macrophage Uptake of Nanoparticles through Surface Modification of Polypeptides with Valine Residues被引量:1
《Chinese Journal of Chemistry》2024年第11期1209-1216,共8页Ning Li Shanshan Xiao Xiaoxiong Jin Ziyuan Song 
supported by the National Natural Science Foundation of China(22101194);Natural Science Foundation of Jiangsu Province(BK20210733);Suzhou Municipal Science and Technology Bureau(ZXL2021447)。
The structural and surface properties of nanomedicines play an important role in determining their biological fate. Surface chemistry of nanomedicines is one of the key parameters, where researchers used various strat...
关键词:NANOPARTICLES Copolymers Structure-activity relationships Surface chemistry POLYPEPTIDE Macrophage uptake 
Targeted screening of an anti-inflammatory polypeptide from Rhopilema esculentum Kishinouye cnidoblasts and elucidation of its mechanism in alleviating ulcerative colitis based on an analysis of the gut microbiota and metabolites
《Food Science and Human Wellness》2024年第3期1336-1347,共12页Ziyan Wang Qiuyue Shi Ying Feng Jiaojiao Han Chenyang Lu Jun Zhou Zhonghua Wang Xiurong Su 
sponsored by the National Key R&D Program of China (2018YFD0901102);the Natural Science Foundation of Zhejiang Province (LQ22D060002);the Fund of State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products (ZS20190105);the Fundamental Research Funds for the Provincial Universities of Zhejiang (SJLY2021015);the K.C.Wong Magna Fund of Ningbo University。
Ulcerative colitis(UC)is a recurrent inflammatory bowel disease that imposes a severe burden on families and society.In recent years,exploiting the potential of marine bioactive peptides for the treatment of diseases ...
关键词:Ulcerative colitis Rhopilema esculentum Kishinouye Cnidoblasts Marine bioactive polypeptides METAGENOME Serum metabolome 
Modulation of polymerization rate of N-carboxyanhydrides in a biphasic system
《Chinese Chemical Letters》2024年第1期326-331,共6页Guonan Ji Xuetao Zheng Xiangdie Hou Xiao Sun Shijie Wang Xiaohong Li Jianjun Cheng Ziyuan Song 
the National Natural Science Foundation of China(No.22101194 for Z.Song and No.52233015 for J.Cheng);Natural Science Foundation of Jiangsu Province(No.BK20210733 for Z.Song);Suzhou Municipal Science and Technology Bureau(No.ZXL2021447 for Z.Song);Collaborative Innovation Center of Suzhou Nano Science&Technology,the 111 Project.,Joint International Research Laboratory of Carbon-Based Functional Materials and Devices,and Suzhou Key Laboratory of Nanotechnology and Biomedicine.
The recent advances in accelerated polymerization of N-carboxyanhydrides (NCAs) offer an effective strategy to simplify the preparation of polypeptide materials. However, the fine-tuning of polymerization kinetics, wh...
关键词:N-CARBOXYANHYDRIDES POLYPEPTIDES Biphasic system Cooperative covalent polymerization Polymerization kinetics 
Polypeptides inhibit HIV-1 replication by interfering viral Vpu-mediated tetherin degradation
《Infectious Medicine》2023年第3期224-228,共5页Shuai Chang Lifeng Cai Yongchang Yang Binlian Sun Jingyun Li Jie Liu Lin Li 
Background:HIV-1 Vpu acts by counteracting the tethering function of tetherin and resulting in the release of HIV-1 virion.Disrupting Vpu-tetherin interactions may provide a promising new target for antiretroviral the...
关键词:ANTIRETROVIRAL HIV-1 POLYPEPTIDE VPU TETHERIN 
Immunomodulatory effect of ethanol-soluble polypeptides from Atlantic cod (Gadus morhua)被引量:1
《Food Science and Human Wellness》2023年第4期1192-1203,共12页Zhen Yuan Meilian Yang Dongyang Zhu Di Wu Shuzhen Cheng Chao Wu Hesham R.El-Seedi Ming Du 
financially supported by the Project of Xingliao Talent Plan“Science and Technology Innovation Leader”(XLYC1802047).
There are many active substances in Atlantic cod(Gadus morhua)explaining the variety of biological activities.In order to study the immunomodulatory activity and the mechanism of Atlantic cod peptides at the cellular ...
关键词:Gadus morhua IMMUNOMODULATION PEPTIDES TLR2 Molecular docking 
Characteristics and functions of Limosilactobacillus reuteri(Lactobacillus reuteri)from the intestine of mice supplemented with three dietary components based on genome resequencing and metabolite analysis
《Food Bioscience》2023年第3期1983-1992,共10页Ziyan Wang Ying Feng Jiaojiao Han Chenyang Lu Jun Zhou Zhonghua Wang Xiurong Su 
sponsored by the Natural Science Foundation of Zhejiang Province(LY19C010003);the Natural Science Foundation of Zhejiang Province(LQ22D060002);the Fund of State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products(ZS20190105);the K.C.Wong Magna Fund of Ningbo University.
Limosilactobacillus reuteri is a resident probiotic in the intestines of animals with strong environmental adaptability.In the current study,to elucidate the adaptation strategies of L.reuteri to the intestine of mice...
关键词:Limosilactobacillus reuteri Whole genome resequencing Intracellular metabolites High DHA tuna Oil Fermented Benincasa hispida culture Rhopilema esculentum polypeptides 
Bioactive fibrous scaffolds with programmable release of polypeptides regulate inflammation and extracellular matrix remodeling被引量:3
《Regenerative Biomaterials》2023年第1期522-532,共11页Zehong Xiang Xinghua Guan Zhifang Ma Qiang Shi Mikhail Panteleev Fazly I.Ataullakhanov 
supported by the financial support of the National Natural Science Foundation of China(52061135202,51573186).
Inflammation manipulation and extracellular matrix(ECM)remodeling for healthy tissue regeneration are critical requirements for tissue engineering scaffolds.To this end,the bioactive polycaprolactone(PCL)-based scaffo...
关键词:bioactive scaffolds inflammation control extracellular matrix remodeling polypeptide release electrospinning 
Thermo-induced physically crosslinked polypeptide-based block copolymer hydrogels for biomedical applications被引量:1
《Regenerative Biomaterials》2023年第1期933-956,共24页Dan Zhao Yan Rong Dong Li Chaoliang He Xuesi Chen 
support from the National Key Research and Development Program of China(2022YFC2604003);National Natural Science Foundation of China(projects 52173147,51973218,52203202,51833010);the Scientific and Technological Development Projects of Jilin Province(20210204136YY).
Stimuli-responsive synthetic polypeptide-containing block copolymers have received considerable attention in recent years.Especially,unique thermo-induced sol-gel phase transitions were observed for elaborately-design...
关键词:injectable hydrogels POLYPEPTIDES stimuli responsive secondary conformation tissue engineering immunotherapy 
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