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作品数：10被引量：10H指数：2
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Dosing strategies for de novo once-daily extended release tacrolimus in kidney transplant recipients based on CYP3A5 genotype
《World Journal of Transplantation》2023年第6期368-378,共11页Adam Diamond Sunil Karhadkar Kenneth Chavin Serban Constantinescu Kwan N.Lau Oscar Perez-Leal Kerry Mohrien Nicole Sifontis Antonio Di Carlo 
Supported by Veloxis Pharmaceuticals,Inc.1001 Winstead Drive Suite 310,Cary,NC 27513.
BACKGROUND Tacrolimus extended-release tablets have been Food and Drug Administrationapproved for use in the de novo kidney transplant population.Dosing requirements often vary for tacrolimus based on several factors ...
关键词：IMMUNOSUPPRESSION Kidney transplant DOSING TACROLIMUS Therapeutic drug monitoring GENOTYPE 
Effect of the transcutaneous electrical stimulation system on esophageal-acid exposure in patients non-responsive to once-daily proton-pump inhibitor:proof-of-concept study
《Gastroenterology Report》2021年第4期323-328,I0002,共7页Ram Dickman Sigal Levy Tsachi Tsadok Perets Maor Hazani-Pauker Doron Boltin Hemda Schmilovitz-Weiss Issa Nidal Matan Siterman Dan Carter Ronnie Fass Rachel Gingold-Belfer 
Background:Gastroesophageal reflux disease(GERD)is a common disorder.Overall,≤35%of GERD patients fail the standard dose of proton-pump-inhibitor(PPI)treatment.Due to the high prevalence and low satisfaction rate wit...
关键词：gastroesophageal reflux disease transcutaneous electrical stimulation system proton-pump inhibitor 
Conversion of twice-daily to once-daily tacrolimus is safe in stable adult living donor liver transplant recipients被引量：4
《Hepatobiliary & Pancreatic Diseases International》2015年第4期374-379,共6页Seong Hoon Kim Seung Duk Lee Young Kyu Kim Sang-Jae Park 
Once-daily extended-release tacrolimus （Tac-OD） has been introduced as a useful therapeutic option to increase patient adherence to immunosuppressive therapy. This study aimed to evaluate the safety, efficacy and im...
关键词：liver transplantation living donor immunosuppressive agents TACROLIMUS 
Safety and Efficacy of Once-Daily Administration of Mycophenolate Mofetil in Kidney Transplant Patients—A New Treatment Option for Non-Adherence
《Journal of Biomedical Science and Engineering》2014年第10期788-791,共4页Naotsugu Ichimaru Kazuaki Yamanaka Taigo Kato Yoichi Kakuta Toyofumi Abe Jun-ya Kaimori Ryoichi Imamura Norio Nonomura Shiro Takahara 
Non-adherence to immunosuppressive therapy is associated with reduced graft survival. Fifteen long-term follow up kidney transplant patients with stable post-transplant clinical courses were enrolled in the study. All...
关键词：ONCE-DAILY ADMINISTRATION MYCOPHENOLATE Mofetil TREATMENT ADHERENCE 
Assessing insulin effectiveness at the end of the day: Once-daily versus twice-daily insulin glargine injection
《Journal of Diabetes Mellitus》2012年第2期203-207,共5页Mark R. Burge Eric R. Schroeder Stephen Mitchell 
Objective: Evidence supporting the twice-daily administration of insulin glargine as an approach to address its waning effectiveness at the end of a 24 hour period is sparse. We hypothesized that insulin concentration...
关键词：INSULIN INJECTION Timing INSULIN GLARGINE BASAL INSULIN Type 1 Diabetes 
Virologic and Lipoprotein Changes after Halving Ritonavir Boosting in HIV-Infected Patients Stabilized on Once-Daily Fosamprenavir plus Abacavir/Lamivudine
《World Journal of AIDS》2012年第2期109-116,共8页Dushyantha T. Jayaweera Gary E. Pakes 
Background: The effect of reducing ritonavir boosting doses on the efficacy and safety of fosamprenavir-based regimens has not been well studied. Methods: In a 52-week, phase 4, open-label, single-center pilot study, ...
关键词：FOSAMPRENAVIR HIV Infection LIPOPROTEINS Ritonavir 
Preparation and <i>in Vitro</i>Drug Release Evaluation of Once-Daily Metformin Hydrochloride Sustained-Release Tablets被引量：1
《Pharmacology & Pharmacy》2012年第4期468-473,共6页Ling Zhao Yumeng Wei Yong Mei Li Yang Yuan You Xufeng Yang Yanhong Jiang 
The objective of this study was to develop once-daily metformin hydrochloride sustained-release tablets (MHSRT) and evaluate their in vitro release behavior. MHSRT were prepared by the film coating method. The in vitr...
关键词：SUSTAINED-RELEASE Tablets METFORMIN HYDROCHLORIDE In Vitro Release Rate Similarity Factor Kinetic Model 
Pharmacokinetics of tacrolimus converted from twice-daily formulation to once-daily formulation in Chinese stable liver transplant recipients被引量：2
《Acta Pharmacologica Sinica》2011年第11期1419-1423,共5页Yi-fan ZHANG Xiao-yan CHEN Xiao-jian DAI Xi-sheng LENG Da-fang ZHONG 
Aim： To evaluate the pharmacokinetics of tacrolimus in Chinese stable liver transplant recipients converted from immediate release （IR） tacrolimus-based immunosuppression to modified release （MR） tacrolimus-based...
关键词：TACROLIMUS modified release clinical pharmacokinetics liver transplantation 
A dynamic model of once-daily 5-aminosalicylic acid predicts clinical efficacy被引量：1
《World Journal of Gastroenterology》2010年第1期136-137,共2页Deepak Parakkal Eli D Ehrenpreis Matthew P Thorpe Karson S Putt Bruce Hannon 
New once daily mesalamine formulations may improve adherence to medication usage.Response to Asacol and other forms of 5-aminosalicyclic acid(5-ASA)is better correlated with tissue concentrations and best predicted by...
关键词：Ulcerative colitis 5-aminosalicylate MESALAZINE Asacol ONCE-DAILY 
Use of new once-daily 5-aminosalicylic acid preparations in the treatment of ulcerative colitis:Is there anything new under the sun?被引量：3
《World Journal of Gastroenterology》2009年第15期1799-1804,共6页Peter Laszlo Lakatos 
5-aminosalicylate(5-ASA)agents remain the mainstay treatment in ulcerative colitis(UC).A number of oral 5-ASA agents are commercially available,including azobond pro-drugs,as well as delayed-and controlledrelease form...
关键词：Ulcerative colitis 5-aminosalicylate MESALAZINE Multi matrix system Therapy ONCE-DAILY Compliance 
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