S-NITROSOGLUTATHIONE

作品数:7被引量:16H指数:3
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相关领域:生物学更多>>
相关作者:段绍瑾苏小游祁鑫王勒渝陈宇霞更多>>
相关机构:中国中医研究院中国中医科学院广安门医院宁波市第一医院浙江大学更多>>
相关期刊:《Acta Pharmacologica Sinica》《中华国际医学杂志》《Neuroscience & Medicine》《Neural Regeneration Research》更多>>
相关基金:国家自然科学基金更多>>
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Therapeutic exploitation of the S-nitrosoglutathione/S-nitrosylation mechanism for the treatment of contusion spinal cord injury被引量:3
《Neural Regeneration Research》2019年第6期973-974,共2页Mushfiquddin Khan Inderjit Singh 
supported by the grants from South Carolina Spinal Cord Injury Research Fund(No.CIRF2017 I-01);VA award(No.RX2090)
Contusion spinal cord injury(SCI)is a major medical and socio-economic problem globally.The incidence of SCI is highest among young adults due to motor vehicle accidents,military or sports injuries,and violence(Selvar...
关键词:CONTUSION SPINAL major medical sports INJURIES 
Hypoxia inducible factor-1 alpha stabilization for regenerative therapy in traumatic brain injury被引量:7
《Neural Regeneration Research》2017年第5期696-701,共6页Mushfiquddin Khan Hamza Khan Inderjit Singh Avtar K.Singh 
supported by grants from VA merit awards(BX3401 and RX2090)
Mild traumatic brain injury(TBI), also called concussion, initiates sequelae leading to motor deficits, cognitive impairments and subtly compromised neurobehaviors. While the acute phase of TBI is associated with ne...
关键词:traumatic brain injury hypoxia inducible factor-1 alpha S-NITROSOGLUTATHIONE NEUROREPAIR functional recovery 
Superoxide and hydrogen peroxide productions by NO-inhibited complex Ⅲ
《BIOCELL》2016年第1期26-29,共4页DARIO E.IGLESIAS SILVINA S.BOMBICINO ALBERTO BOVERIS LAURA B.VALDEZ 
supported by research grants from the University of Buenos Aires(UBACYT 200-201-101-00140 and 200-201-301-00731);Agencia Nacional de Promoción Científica y Tecnológica(PICT 2012-0964);Consejo Nacional de Investigaciones Científicas y Técnicas(PIP 112-201-101-00444).
Complex Ⅲ plays a central role in the mitochondrial respiratory chain transferring electrons from ubiquinol to cytochrome c and pumping protons to the intermembrane space,contributing to the protonmotive force.Furthe...
关键词:S-nitrosoglutathione(GSNO) spermine-NONOate(SPER-NO) electron paramagnetic resonance(EPR) ubisemiquinone 
S-Nitrosoglutathione Administration Ameliorates Cauda Equina Compression Injury in Rats被引量:1
《Neuroscience & Medicine》2012年第3期294-305,共12页Anandakumar Shunmugavel Mushfiquddin Khan Marcus M. Martin Anne G. Copay Brian R. Subach Thomas C. Schuler Inderjit Singh 
Lumbar spinal stenosis (LSS) causes ischemia, inflammation, demyelination and results in cauda equina (CE) syndrome, with pain and locomotor functional deficits. We investigated whether exogenous administration of S-n...
关键词:LSS VEGF DEMYELINATION g-Ratio NEUROPROTECTION 
Protective effects of S-nitrosoglutathione against amyloid beta-peptide neurotoxicity
《中国生物学文摘》2006年第10期7-7,共1页Ju TC Chert SD Liu CC Yang DI 
关键词:阿耳茨海默氏病 早老性痴呆 淀粉样β-缩氨酸 神经毒性 保护效应 
S-Nitrosoglutathione and glutathione act as NMDA receptor agonists in cultured hippocampal neurons被引量:5
《Acta Pharmacologica Sinica》2006年第7期853-860,共8页Ting-yu CHIN~2 Sheau-huei CHUEH~(3,5) Pao-luh TAO~42 Department of Bioseience Technology,Chung-Yuan Christian University,Chung-Li,Taiwan,China 3 Department of Biochemistry,National Defense Medical Center,Taipei,Taiwan,China 4 Department of Pharmacology,National Defense Medical Center Taipei,Taiwan,China 
Project supported by grants from the National Science Council,Taiwan,China (NSC93-2311-B033-002 to TYC and NSC93-2320-B016-043 to SHC).
Aim: To characterize the effect of combined pre- and postnatal morphine exposure on N-methyl-D-aspartate receptor (NMDA) receptor signaling in hippocampal neurons of the offspring of morphine-addicted female rats. ...
关键词:cytosolic Ca^2+ concentration S-NITROSOGLUTATHIONE GLUTATHIONE cultured hippocampal neuron MORPHINE GLUTAMATE N-methyl-D-aspartate receptor 
S-nitrosoglutathione诱导胸腺细胞凋亡的机制
《中华国际医学杂志》2003年第6期476-480,共5页苏小游 段绍瑾 陈宇霞 潘健 祁鑫 
目的 研究NO供体亚硝酰谷胱甘肽(GSNO)诱导胸腺细胞凋亡与p53表达的相互关系。方法 体外培养:BALB/C小鼠胸腺细胞,用地塞米松(DXM)作为阳性对照,再分别加不同剂量GSNO及NO抑制剂,孵育3h。用透射电镜观察胸腺细胞形态;用琼脂糖凝...
关键词:细胞凋亡 胸腺细胞 一氧化氮 亚硝酸谷胱甘肽 P53 S-NITROSOGLUTATHIONE 地塞米松 
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