INDAZOLES

作品数：7被引量：11H指数：2
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相关领域：理学更多>>
相关作者：张均田谭启涛许斌丁正伟王晓英更多>>
相关机构：中国医学科学院中国协和医科大学上海大学淮北师范大学浙江工业大学更多>>
相关期刊：《Acta Pharmacologica Sinica》《Science China Chemistry》《Chinese Medical Sciences Journal》《Chinese Journal of Chemistry》更多>>
相关基金：国家自然科学基金上海市教育委员会创新基金国家重点实验室开放基金更多>>
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Metal-Free Nitration of Indazoles with tert-Butyl Nitrile in Air to Prepare 3-Nitroindazoles and 3-Aminoindazoles
《Chinese Journal of Chemistry》2025年第4期393-398,共6页Xin-Yue Zhang Rong-Ting Jiang Xiu-Qun Pan Chun-Hua Chen Cui Liang Dong-Liang Mo 
the NSFC(22071035);Natural Science Foundation of Guangxi(2023GXNSFDA026025);Guangxi Bagui Young Scholar is greatly appreciated.
A variety of 3-nitroindazoles and 3-aminoindazoles were prepared in good to excellent yields with high regioselectivity through TBN-mediated nitration at the C3-position of indazoles under the air conditions and seque...
关键词：NITRATION INDAZOLE 3-Nitroindazole 3-Aminoindazole C-H Amination Radical reactions N-HETEROCYCLES Cleavage reactions 
Single-atom skeletal editing of 2H-indazoles enabled by difluorocarbene被引量：1
《Science China Chemistry》2023年第7期1975-1981,共7页Yao Zhou Fuling Chen Ziru Li Junjie Dong Jingnan Li Bohao Zhang Qiuling Song 
supported by the National Natural Science Foundation of China(21931013,22271105);the Natural Science Foundation of Fujian Province(2022J02009);the Science and Technology Research Project of Education Department of Hubei Province(B2021133);the Hubei Key Laboratory of Pollutant Analysis&Reuse Technology(PA190109)
A novel difluorocarbene promoted single-atom skeletal editing of 2H-indazoles is demonstrated herein.Ethyl bromodifluoroacetate was severed as the difluorocarbene source in the current protocol,facilitating the cleava...
关键词：INDAZOLES skeletal editing DIFLUOROCARBENE N-N bond cleavage quinazolin-4(3H)-ones 
Synthesis of 2H-benzo[g]furo/thieno/pyrrolo[2,3-e]indazoles via Intramolecular Dehydrogenation Photocyclization被引量：2
《Chinese Journal of Chemistry》2021年第8期2213-2219,共7页Wei Zhang Ping Wang Xi Zhang Rui Wang Tao Wang Zhicun Liu Zunting Zhang 
We are grateful for financial support by the National Natural Science Foundation of China(No.21672132).
A catalyst-,acid-and base-free,environmental-friendly method for synthesis of 2/7-benzo[g]furo[2,3-e]indazoles,2H-benzo[g]-thieno[2,3-e]indazoles and 2H-benzo[g]pyrrolo[2,3-e]indazoles via UV light irradiation of 3-ph...
关键词：INDAZOLES 6π-electroncyclization PHOTOCYCLIZATION Dehydrogenative annulation Chemo-selectivity 
Synthesis of 1-Aryl-1 H-indazoles via a Ligand-Free Copper- Catalyzed Intramolecular Amination Reaction
《Chinese Journal of Chemistry》2011年第6期1199-1204,共6页Gao, Mingshan Liu, Xiujie Wang, Xianyang Cai, Qian Ding, Ke 
Project supported by the National Natural Science Foundation of China＇（Nol 21002102）, and State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences （No. 10184）.
A general synthesis of 1-aryl-l-H-indazoles from o-halogenated aryl aldehydes or ketones and aryl hydrazines was described. This protocol included an intermolecular condensation and a ligand-free copper-catalyzed intr...
关键词：COPPER AMINATION ligand free 
NO mediates ginsenoside Rg<sub>1</sub>-induced long-term potentiation in anesthetized rats
《Acta Pharmacologica Sinica》2001年第12期45-48,共页王晓英 张均田 
AIM: To investigate the effect of ginsenoside Rg1 on synaptic transmission in anesthetized rats and the effect of NOS inhibitor, 7-nitroindazole (7-NI), on long-term potentiation (LTP) induced by Rgj. METHODS: Extrace...
关键词：GINSENG SAPONINS long-term potentia-tion synaptic transmission nitric oxide INDAZOLES hippocampus dentate gyrus ARGININE 
NO mediates ginsenoside Rg_1-induced long-term potentiation in anesthetized rats被引量：7
《Acta Pharmacologica Sinica》2001年第12期1099-1102,共4页王晓英 张均田 
National Key Program on Basic Research and Development, No g1998051109
AIM: To investigate the effect of ginsenoside Rg1 on synaptic transmission in anesthetized rats and the effect of NOS inhibitor, 7-nitroindazole (7-NI), on long-term potentiation (LTP) induced by Rgj. METHODS: Extrace...
关键词：GINSENG SAPONINS long-term potentia-tion synaptic transmission nitric oxide INDAZOLES HIPPOCAMPUS dentate gyrus ARGININE 
Synthesis and Radiosensitizing Effects of Indazoles Derivatives被引量：1
《Chinese Medical Sciences Journal》1995年第1期11-11,共1页王荣先 施培基 胡壁 饶尔昌 糜福顺 李政 沈渝 
ＳｙｎｔｈｅｓｉｓａｎｄＲａｄｉｏｓｅｎｓｉｔｉｚｉｎｇＥｆｆｅｃｔｓｏｆＩｎｄａｚｏｌｅｓＤｅｒｉｖａｔｉｖｅｓＷａｎｇＲｏｎｇｘｉａｎ（王荣先）；ＳｈｉＰｅｉｊｉ（施培基）；ＨｕＢｉ（胡壁）；ＲａｏＥｒｃｈａｎｇ...
关键词：吲唑派生物 辐射致敏作用 合成工艺 肿瘤细胞 亲水性 
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