SONOPORATION

作品数:11被引量:62H指数:4
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相关领域:医药卫生生物学更多>>
相关期刊:《Acta Biochimica et Biophysica Sinica》《World Journal of Gastroenterology》《Chinese Medical Journal》《World Journal of Methodology》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划更多>>
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Development of exosome membrane materialsfused microbubbles for enhanced stability and efficient drug delivery of ultrasound contrast agent被引量:3
《Acta Pharmaceutica Sinica B》2023年第12期4983-4998,共16页Yongho Jang Jeehun Park Pilsu Kim Eun-Joo Park Hyungjin Sun Yujin Baek Jaehun Jung Tai-kyong Song Junsang Doh Hyuncheol Kim 
supported by the Basic Science Research Program through the National Research Foundation of Korea(NRF);funded by the Ministry of Education,Science,and Technology(NRF-2016R1A6A1A03012845,NRF-2022M3E5F1017553),Republic of Korea;the Ministry of Food and Drug Safety grant(22213MFDS421),Republic of Korea.
Lipid-coated microbubbles are widely used as an ultrasound contrast agent,as well as drug delivery carriers.However,the two main limitations in ultrasound diagnosis and drug delivery using microbubbles are the short h...
关键词:EXOSOMES MICROBUBBLES Photodynamic therapy ULTRASOUND SONOPORATION Cancer immunotherapy Drug delivery 
Ultrasound-Mediated Drug Delivery:Sonoporation Mechanisms,Biophysics,and Critical Factors被引量:2
《Biomedical Engineering Frontiers》2022年第1期14-30,共17页Juan Tu Alfred C.H.Yu 
supported in part by the Natural Sciences and Engineering Council of Canada (CREATE-528202-2019);Canadian Institutes of Health Research (PJT-153240);the Ministry of Science and Technology Key Research and Development Plan of China (No.2018YFC0115901);the National Natural Science Foundation of China (Grant No.11774168).
Sonoporation,or the use of ultrasound in the presence of cavitation nuclei to induce plasma membrane perforation,is well considered as an emerging physical approach to facilitate the delivery of drugs and genes to liv...
关键词:CAVITATION BUBBLE REALIZATION 
Clinical study of ultrasound and microbubbles for enhancing chemotherapeutic sensitivity of malignant tumors in digestive system被引量:12
《Chinese Journal of Cancer Research》2018年第5期553-563,共11页Yanjie Wang Yan Li Kun Yan Lin Shen Wei Yang Jifang Gong Ke Ding 
sponsored by National Key Research and Development Plan(No.2017YFC0107300 and No.2017YFC0107303)
Objective: To explore the safety of ultrasound and microbubbles for enhancing the chemotherapeutic sensitivity of malignant tumors in the digestive system in a clinical trial, as well as its efficacy.Methods: From O...
关键词:Clinical study SONOPORATION MICROBUBBLES CHEMOTHERAPY digestive system 
Advances in ultrasound-targeted microbubble-mediated gene therapy for liver fibrosis被引量:8
《Acta Pharmaceutica Sinica B》2017年第4期447-452,共6页Cuiyuan Huang Hong Zhang Ruidan Bai 
Hepatic fibrosis develops as a wound-healing scar in response to acute and chronic liver inflammation and can lead to cirrhosis in patients with chronic hepatitis B and C. The condition arises due to increased synthes...
关键词:Liver fibrosis Ultrasound-targeted microbubbles Gene therapy Gene delivery CAVITATION SONOPORATION 
Microflow-induced shear stress on biomaterial wall by ultrasound-induced encapsulated microbubble oscillation被引量:1
《Chinese Physics B》2015年第9期307-312,共6页胡继文 钱盛友 孙佳娜 吕云宾 胡苹 
Projects supported by the National Natural Science Foundation of China(Grant Nos.11174077 and 11474090);the Natural Science Foundation of Hunan Province,China(Grant No.13JJ3076);the Science Research Program of Education Department of Hunan Province,China(Grant No.14A127);the Doctoral Fund of University of South China(Grant No.2011XQD46)
A model of an ultrasound-driven encapsulated microbubble(EMB) oscillation near biomaterial wall is presented and used for describing the microflow-induced shear stress on the wall by means of a numerical method. The...
关键词:encapsulated microbubble shear stress SONOPORATION 
Microstreaming velocity field and shear stress created by an oscillating encapsulated microbubble near a cell membrane被引量:3
《Chinese Physics B》2014年第12期270-276,共7页王莉 屠娟 郭霞生 许迪 章东 
Projects supported by the National Basic Research Program,China(Grant No.2011CB707900);the National Natural Science Foundation of China(Grant Nos.81127901,81227004,81271589,11374155,11161120324,11074123,11174141,11274170,11104140,11474001,and 11474161);the National High Tech Research and Development Program,China(Grant No.2012AA022702);the Program for New Century Excellent Talents in University of Ministry of Education of China(Grant No.NCET-11-0236)
Sonoporation mediated by microbubbles is being extensively studied as a promising technology to facilitate gene/drug delivery to cells. However, the theoretical study regarding the mechanisms involved in sonoporation ...
关键词:microstreaming shear stress SONOPORATION encapsulated microbubbles 
Sonoporation:Gene transfer using ultrasound被引量:5
《World Journal of Methodology》2013年第4期39-44,共6页Minoru Tomizawa Fuminobu Shinozaki Yasufumi Motoyoshi Takao Sugiyama Shigenori Yamamoto Makoto Sueishi 
Genes can be transferred using viral or non-viral vectors.Non-viral methods that use plasmid DNA and short interference RNA(si RNA)have advantages,such as low immunogenicity and low likelihood of genomic integration i...
关键词:Gene therapy CAVITY MICROBUBBLES Con-trast agent DIAGNOSTIC ULTRASOUND 
Enhancing microRNA transfection to inhibit survivin gene expression and induce apoptosis: could it be mediated by a novel combination of sonoporation and polyethylenimine?被引量:3
《Chinese Medical Journal》2011年第21期3592-3594,共3页CHEN Zhi-yi LIANG Kun QIU Ri-xiang LUO Liang-ping 
Apoptosis is a physiologically essential mechanism of cell and plays an important role in reducing the development and progression of tumors. The appealing strategy for cancer therapy is to target the lesions that ind...
关键词:ULTRASOUND microRNA apoptosis cancer TRANSFECTION 
Contrast-enhanced and targeted ultrasound被引量:22
《World Journal of Gastroenterology》2011年第1期28-41,共14页Michiel Postema Odd Helge Gilja 
Ultrasonic imaging is becoming the most popular medical imaging modality,owing to the low price per examination and its safety.However,blood is a poor scatterer of ultrasound waves at clinical diagnostic transmit freq...
关键词:ULTRASOUND Drug delivery systems Drug targeting SONOPORATION Contrast media LIVER PANCREAS Gastrointestinal tract 
Low-frequency ultrasound increases non-viral gene transfer to the mouse lung被引量:3
《Acta Biochimica et Biophysica Sinica》2010年第1期45-51,共7页Stefania Xenariou Hai-Dong Liang Uta Griesenbach Jie Zhu Raymond Farley Lucinda Somerton Charanjit Singh Peter K. Jeffery Ronald K. Scheule Seng H. Cheng Duncan M. Geddes Martin Blomley Eric W. F. W. Alton 
The aim of the study was to assess if low-frequency ultrasound (US), in the range of 30-35 kHz, increases non-viral gene transfer to the mouse lung. US is greatly attenuated in the lung due to large energy losses at...
关键词:low-frequency ultrasound SONOPORATION gene transfer non-viral vector LUNG cystic fibrosis 
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