MICAFUNGIN

作品数:11被引量:19H指数:2
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相关领域:医药卫生更多>>
相关作者:钱秀萍陈代杰王栋海更多>>
相关机构:上海来益生物药物研究开发中心上海师范大学郑州大学更多>>
相关期刊:《药学进展》《Open Journal of Medical Microbiology》《International Journal of Ophthalmology(English edition)》《Chinese Medical Journal》更多>>
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Efficacy and Safety Assessment of Antifungal Sequential Therapy from Micafungin to Liposomal Amphotericin B for Antibiotics-Refractory Febrile Neutropenia in Patients with Hematologic Malignancies
《Advances in Microbiology》2023年第6期315-322,共8页Kazunori Nakase Koji Oka Keiki Kawakami Tetsuya Tsukada Shigehisa Tamaki Atsushi Fujieda 
Invasive fungal infections are a major challenging problem in the management of febrile neutropenia (FN) in patients with hematologic malignancies. Liposomal amphotericin B (L-AmB) or micafungin (MCFG) has been widely...
关键词:Empirical Antifungal Therapy MICAFUNGIN Liposomal Amphotericin B Febrile Neutropenia Hematologic Malignancy 
Based on PK/PD and Monte Carlo Simulation Analysis of the Dosing Regimens of Micafungin in Children with Febrile Neutropenic
《Open Journal of Pediatrics》2022年第4期711-717,共7页Jiuli Hu Ying Wang Junhui Hu Xiaolei Yu Xiaoqin Zhu 
Neutropenia with fever is a special group of patients. Due to low immune function, inflammation-related clinical symptoms and signs are often not obvious, and pathogenic bacteria and infection focus are not clear. Fev...
关键词:PK/PD Model Mote Carlo Simulation MICAFUNGIN Febrile Neutropenic 
Optimizing the Dosage Regimen of Micafungin against <i>Candida spp</i>in HIV Positive Patients with EC Based on Mote Carlo Simulation被引量:1
《Open Journal of Preventive Medicine》2020年第6期120-125,共6页Ying Wang Jingyi Zhao Song Jiang Yinhui Yao Hainan Wen 
The objective of our study was to explore the possibility of the antifungal efficacy of various micafungin dosage regimens against Candida spp in HIV positive patients with EC. According to pharmacokinetic/phar...
关键词:Monte Carlo Simulation MICAFUNGIN HIV Positive Patients Esophageal Candidiasis 
Pharmacokinetics of Micafungin in Adult Patients with Invasive Candidiasis and Candidemia
《Open Journal of Medical Microbiology》2012年第3期84-90,共7页Nasrullah A. Undre Paul Stevenson Ernst-Rüdiger Kuse Ignace Demeyer 
Micafungin is an efficacious and well-tolerated echinocandin with in vitro and in vivo activity against a broad range of Candida species. The objective of this randomized, double-blind study was to examine the pharmac...
关键词:MICAFUNGIN PHARMACOKINETICS INVASIVE CANDIDIASIS CANDIDEMIA 
Efficacy and safety of micafungin for invasive candida infections:a meta-analysis of randomized controlled trials被引量:4
《Chinese Medical Journal》2012年第2期345-351,共7页Chen Qian Lin Mao-hu Chen Meng-li Liu Zhe-yuan Chai Dong Wang Rui 
Background Invasive fungal infections such as candidiasis and mold infections cause significant morbidity and mortality in seriously ill patients.Micafungin is an echinocandin antifungal agent with potent activity aga...
关键词:MICAFUNGIN META-ANALYSIS invasive candida infections antifungal agent 
Endogenous aspergillus endophthalmitis after kidney transplantation
《International Journal of Ophthalmology(English edition)》2011年第5期567-571,共5页Huan-Huan Cheng, Jin-Tang Xu 
Endogenous aspergillus endophthalmitis(EAE) after kidney transplant is a rare but important clinical problem due to potentially devastating consequences. Early diagnosis of EAE, timely removal of affected vitreous by ...
关键词:ASPERGILLUS ENDOPHTHALMITIS kidney transplan-tation amphotercin B MICAFUNGIN 
Astellas公司的一连串产品申请
《国外药讯》2006年第7期49-49,共1页张振华(摘) 
Astellas药物公司已将他克莫司(tacromlimus)(每日一次)制剂的上市申请递交给欧洲药品管理局EMEA。该免疫抑制剂的主要适应症是用于器官移植的排斥反应。Astellas公司曾于去年12月份在美国提出相似的申请,且正在日本进行Ⅱ期临床...
关键词:公司 MICAFUNGIN Ⅱ期临床试验 造血干细胞移植 免疫抑制剂 附加适应症 产品 肠易激综合征 雷莫司琼 药品管理局 
FDA批准micafungin用于预防和治疗念珠菌感染
《世界临床药物》2005年第5期257-257,共1页
2005年3月,FDA批准日本藤泽公司(Fujisawa)的micafungin sodlium注射液(Mycamirle)用于预防行造血干细胞移植术患者的念珠菌感染及治疗食道念珠菌感染。但本品对除念珠菌以外的其他真菌感染的疗效尚待验证。
关键词:MICAFUNGIN 念珠菌感染 FDA批准 预防和治疗 造血干细胞移植术 2005年 真菌感染 注射液 
FDA最新药物
《中国处方药》2005年第4期84-85,共2页卢康荣 
关键词:MICAFUNGIN 新药物 FDA批准 新药上市申请 骨质疏松症 抗真菌药物 长效制剂 糖尿病 治疗 
抗真菌药物echinocandins和pneumocandins类的研究进展被引量:12
《中国抗生素杂志》2004年第7期439-442,i004,共5页王栋海 钱秀萍 陈代杰 
新型抗真菌药物 echinocandins与 pneumocandins类的作用机制是能够非竞争性的抑制真菌细胞壁中 β- 1,3-葡聚糖合成酶的活性 ,进而引起真菌细胞壁的裂解以及细胞内外渗透压的改变从而将真菌细胞彻底杀死。本文综述了这两类药物的研究进...
关键词:抗真菌药物 ECHINOCANDINS Pneumocandins CASPOFUNGIN MICAFUNGIN ANIDULAFUNGIN 
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