ACITRETIN

作品数：16被引量：35H指数：3
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Impact of Adverse Events Associated With Acitretin Treatment of Moderate-to-Severe Plaque Psoriasis:Based on an Observational,Single-Center Study in Shanghai,China
《International Journal of Dermatology and Venereology》2023年第2期61-66,共6页Xiao-Yuan Zhong Ying Li Rui Ma Xin Wang Ying-Yuan Yu Ning Yu Yang-Feng Ding Jia-Jing Lu Yu-Ling Shi 
sponsored by the National Natural Science Foundation of China(Nos.81872522,82073429,82203913);Youth Program of National Natural Science Foundation of China(No.82003335);Innovation Program of Shanghai Municipal Education Commission(No.2019-01-07-00-07-E00046);Clinical Research Plan of SHDC(Nos.SHDC2020CR1014B and SHDC2020CR6022),Program of Shanghai Academic Research Leaders(No.20XD1403300);Program of Science and Technology Commission of Shanghai Municipality(No.18140901800);Excellent Subject Leader Program of Shanghai Municipal Commission of Health and Family Planning(No.2018BR30);Clinical Training Program(No.lcfy2020-02);Fundamental Research Funds for the Central Universities(22120220602).
Objective:Acitretin is a widely used systemic retinoid that is to treat psoriasis but has significant variations in efficacy and adverse events(AEs)among individuals.This study aimed to determine the impact of AEs ass...
关键词：plaque psoriasis ACITRETIN adverse events Dermatology Life Quality Index Hospital Anxiety and Depression Scale 
Efficacy of Acitretin Monotherapy on Basal Cell Carcinoma:A Case Report
《International Journal of Dermatology and Venereology》2022年第3期172-174,共3页Ping-Jiao Chen Jing-Yao Liang Xin Tian Chang-Xing Li Xi-Bao Zhang 
the Natural Science Foundation of Guangdong(No.2020A1515010275);Characteristic Clinic Project of Guangzhou Health Commission(No.2019TS68);the Medical and Health Technology Projects of Guangzhou(No.20191A010052).
Introduction:Basal cell carcinoma(BCC)is the most common skin cancer which mainly affects the population over 50 years of age.In addition to surgical treatment,nonsurgical treatment is also an attractive option for so...
关键词：ACITRETIN MONOTHERAPY basal cell carcinoma 
A harlequin ichthyosis pig model with a novel ABCA12 mutation can be rescued by acitretin treatment被引量：2
《Journal of Molecular Cell Biology》2019年第12期1029-1041,共13页Xiao Wang Chunwei Cao Yongshun Li Tang Hai Qitao Jia Ying Zhang Qiantao Zheng Jing Yao Guosong Qin Hongyong Zhang Ruigao Song Yanfang Wang Guanghou Shui Sin Man Lam Zhonghua Liu Hong Wei Anming Meng Qi Zhou Jianguo Zhao 
the Strategic Priority Research Programs of CAS(XDA16030300);the National Natural Science Foundation of China(81671274,31272440,and 31801031);the National Transgenic Project of China(2016ZX08009003-006-007);the Elite Youth Program of the Chinese Academy of Agricultural Sciences(ASTIP-IAS05).
Harlequin ichthyosis (HI) is a severe genetic skin disorder and caused by mutation in the ATP-binding cassette A12 (ABCA12) gene. The retinoid administration has dramatically improved long-term survival of HI, but imp...
关键词：harlequin ichthyosis ABCA12 pig model ACITRETIN ENU mutagenesis deep intronic mutation 
Combination Therapy of Acitretin Capsule and Chinese Herbs for Patients with Lichen Planus Pigmentosus-Inversus被引量：2
《Chinese Journal of Integrative Medicine》2019年第12期922-925,共4页CHEN Yu XUE Liang GUO Dong-jie MAO Jing-yi WU Min-feng XU Rong LI Xin LI Bin LI Fu-lun 
Supported by the National Science Foundation of China(No.81673866);the Dawn Plan of Shanghai Education Commission and Shanghai Education Development Foundation(No.17SG41);the Project of Shanghai Health and Family Planning Committee(No.ZYKC201703002);Nova of the Seventh People’s Hospital of Shanghai(No.XX2019-05);the Project of Pudong New Area Health and Family Planning Committee(No.PWZ6r2017-05)
Lichen planus pigmentosus-inversus(LPPI)is a relatively uncommon variant of lichen planus(LP),characterized by mottled pigmentation of bluish,black or grey color on the flexural folds with or without itch.It was first...
关键词：DIAGNOSIS THERAPY PATIENTS 
Role and mechanism of matrine alone and combined with acitretin for HaCaT cells and psoriasis-like murine models被引量：11
《Chinese Medical Journal》2019年第17期2079-2088,共10页Wei-Wei Jiang Yi-Meng Wang Xiao-Yu Wang Qian Zhang Si-Man Zhu Chun-Lei Zhang 
Background: Acitretin and matrine have been used in the treatment of psoriasis in China. This study was designed to investigate the role and related mechanisms of matrine alone and in combination with acitretin in the...
关键词：Psoriasis Autophagy PHOSPHOINOSITIDE 3-kinase Protein KINASE B Mammalian target of RAPAMYCIN 
Erythrokeratoderma variabilis in a 3-year-old child:a satisfactory response to treatment with oral acitretin and topical 0.025% tretinoin cream
《International Journal of Dermatology and Venereology》2018年第4期232-234,共3页Yan Teng Jian-Fang Sun Yi Liu 
Introduction Erythrokeratoderma variabilis is a rare autosomal dominant genodermatosis that usually appears within the first year of life, but may arise later in childhood. EKV was described by Mendes da Costa in 1925...
关键词：Erythrokeratoderma variabilis a satisfactory response 
Eruptive Keratoacanthomas within a Red Ink Tattoo: A Case Report
《Case Reports in Clinical Medicine》2018年第8期470-475,共6页Brayden Healey William Galbraith Yasser M. Sammour Diane Baird 
Background: There has been a longstanding debate regarding whether keratoacanthomas (KAs) are neoplastic or reactive/inflammatory lesions. Aim: The aim of this case report is to, within the aforementioned debate, offe...
关键词：KERATOACANTHOMA SQUAMOUS Cell Carcinoma TATTOO Red INK ACITRETIN 
Evaluation of the Therapeutic Response and Improvement in the Quality of Life of the Patient with Darier Disease to Acitretin through an Analogy between Close Relatives
《Journal of Biosciences and Medicines》2017年第8期48-54,共7页Thiago Sande Miguel Mateus de Oliveira Reis Bruno Fonseca dos Santos Aline da Silva Rocha Nayrton Kalys Cruz dos Anjos Lívia Cristina de Melo Pino Daniel Almeida da Costa 
Darier disease (DD), also known as follicular keratosis, is a rare autosomal dominant hereditary acantholytic dermatosis caused by a mutation in the ATP2A2 gene. Skin lesions are characterized by persistent confluent ...
关键词：Darier’s Disease FOLLICULAR KERATOSIS HEREDITARY DERMATOSIS 
Efficacy and Safety of Tripterygium wilfordii Hook F Versus Acitretin in Moderate to Severe Psoriasis Vulgaris：A Randomized Clinical Trial被引量：14
《Chinese Medical Journal》2015年第4期443-449,共7页Chao Wu Hong-Zhong Jin Dan Shu Feng Li Chun-Xia He Ju Qiao Xiao-Ling Yu 
Background：Few clinical trials have evaluated the efficacy and safety of Tripterygium wilfordii Hook F （TwHF） compared with acitretin in psoriasis.We aimed to compare the efficacy and safety of TwHF compared with a...
关键词：ACITRETIN PSORIASIS Tripterygium wilfordii Hook F 
Assessment by HPLC of the degradation behavior of acitretin under hydrolytic,oxidative,photolytic and thermal stress conditions被引量：1
《Acta Pharmaceutica Sinica B》2014年第6期438-446,共9页Pawan K.Porwal Neeraj Upmanyu 
Acitretin is a photosensitive oral retinoid with very limited data available on its degradation.The official HPLC method for acitretin determination was insufficient to resolve the degradation products generated durin...
关键词：ACITRETIN Degradation kinetics Photolytic degradation VALIDATION 
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