MONOTHERAPY

作品数：116被引量：451H指数：11
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Dexamethasone intravitreal implant monotherapy in naive patients with macular edema secondary to retinal vein occlusion:long term follow-up retrospective cohort study
《International Journal of Ophthalmology(English edition)》2025年第5期876-882,共7页Gamze Karataş AkınÇakır Tahsin Uzundede Öznur Aday Ahmet MelihÖzoğuz Mehmet Egemen Karataş AslıKırmacıKabakcı 
AIM:To investigate the efficacy and safety of repeated dexamethasone implants with real-life data in eyes with naive retinal vein occlusion(RVO)with macular edema(ME)at a minimum of 60mo follow-up.METHODS:In this retr...
关键词：DEXAMETHASONE intravitreal naïve retinal vein occlusion macular edema 
Sucroferric oxyhydroxide monotherapy for hyperphosphatemia in Indian chronic kidney disease patients undergoing hemodialysis:A phase IV,single-arm,open-label study
《World Journal of Nephrology》2025年第2期105-113,共9页M R Niranjan Sanjay Srinivasa Vibhanshu Gupta Anil K Bhalla Ankush Gaikwad Prajakta Wangikar Sachin Suryawanshi Priti Gajbe 
BACKGROUND Hyperphosphatemia(HP)is a common complication in an advanced stage of chronic kidney disease(CKD)and is associated with cardiovascular issues,metabolic bone abnormalities and worsening of secondary hyperpar...
关键词：Chronic kidney disease Dynulta™ HEMODIALYSIS HYPERPHOSPHATEMIA Iron-based phosphate binder Sucroferric oxyhydroxide 
AGTR1 A1166C gene polymorphism is associated with the effectiveness of valsartan monotherapy in Chinese patients with essential hypertension:A retrospective analysis
《Asian Pacific Journal of Tropical Medicine》2024年第9期418-424,共7页Hanzhong Yu Lei Li Shuyao Wei Qianqian Kong Wei Nu Bo Dong Yuewu Zhao Li Wang 
Science and Technology Key Project of Xuzhou Municipal Health Commission,Jiangsu Province,China(XWKYHT20210531);Pengcheng Yingcai-Medical Young Reserve Talent Programme(XWRCHT20220013).
Objective:To investigate whether angiotensinⅡtype 1 receptor(AGTR1 A1166C)gene polymorphism was associated with the effectiveness of valsartan monotherapy in Chinese patients with essential hypertension.Methods:This ...
关键词：Essential hypertension AngiotensinⅡtype 1 receptor antagonist VALSARTAN AGTR1 A1166C Gene polymorphism 
Value of baseline ^(18)F-FDG PET/CT metabolism parameters in patients with stage Ⅲ-Ⅳ lung adenocarcinoma before EGFR-TKI monotherapy
《China Medical Abstracts(Internal Medicine)》2024年第3期130-131,共2页CUI Yan 
Objective To investigate the efficacy and prognostic value of baseline ^(18)F-FDG PET/CT metabolism parameters in patients with stageⅢ-Ⅳlung adenocarcinoma before epidermal growth factor receptor tyrosine kinase inh...
关键词：PET/CT TKI BEFORE 
IBI310(anti-CTLA-4 antibody)monotherapy or in combination with sintilimab in advanced melanoma or urothelial carcinoma
《The Innovation》2024年第4期34-40,33,共8页Chuanliang Cui Juan Li Yue Yang Lu Si Zhihong Chi Lili Mao Xuan Wang Bixia Tang Xieqiao Yan Siming Li Li Zhou Xiaoting Wei Yuping Shen Qun Guo Shirui Zheng Jun Guo Bin Lian 
supported by grants from Beijing Health Technologies Promotion Program(BHTPP2022041);Peking University Clinical Scientist Training Program,the Fundamental Research Funds for the Central Universities(BMU2024PYJH010);Beijing Municipal Administration of Hospitals Incubating Program(PX2021046);Science Foundation of Peking University Cancer Hospital(PY202333);Innovent Biologics,Inc.,Suzhou,China.The funder,Innovent Biologics,was involved in the study design,data collection,data analysis,and data interpretation.
IBI310 is a recombinant fully human IgG1 antibody against cytotoxic T lymphocyte antigen 4.This study was conducted to evaluate IBI310 monotherapy or combination therapy with sintilimab in the patients with advanced m...
关键词：MELANOMA MONO experienced 
Efficacy comparison of fruquintinib,regorafenib monotherapy or plus programmed death-1 inhibitors for microsatellite stable metastatic colorectal cancer
《World Journal of Gastrointestinal Oncology》2024年第6期2449-2462,共14页Tian-Qi An Hui Qiu Quan-Bo Zhou Hong Zong Shuang Hu Yu-Gui Lian Rui-Hua Zhao 
BACKGROUND Regorafenib(R)and fruquintinib(F)are the standard third-line regimens for colorectal cancer(CRC)according to the National Comprehensive Cancer Network guidelines,but both have limited efficacy.Several phase...
关键词：Colorectal cancer Fruquintinib REGORAFENIB Programmed death-1 inhibitor Real-world 
SGLT2 inhibitor monotherapy alleviates hyperglycemia in heredity severe insulin resistance syndrome
《Chinese Medical Journal》2024年第11期1372-1374,共3页Huixuan Wu Junaid Iqbal Long Li Hongli Jiang Chen Chao Meibiao Zhang Ou Li Houde Zhou 
National Natural Science Foundation of China(Nos.8217033609,81770880,and 81970762);Science&Technology Department of Hunan Province(Nos.2020SK2080 and 2015JC3012);Science&Technology Department of Changsha City(Nos.k1906019 and kq190111)
To the Editor:Hereditary severe insulin resistance syndrome(H-SIRS)shows a wide and variable clinical spectrum and results in severe complications in the endocrinological and cardiovascular systems.Multiple treatments...
关键词：SIRS CARDIOVASCULAR clinical 
Long-term complete response to anti-programmed-death-1 monotherapy in a patient with relapsed and refractory ovarian adenocarcinoma: A case report
《World Journal of Clinical Cases》2024年第11期1967-1973,共7页Guang-Di Zhou Qin Li 
BACKGROUND Ovarian cancer is the most common malignant tumor of the female reproductive system,and the survival rate of patients with relapsed and refractory ovarian cancer is very low.CASE SUMMARY Here,we report a ca...
关键词：Anti-programmed cell death-1 Tislelizumab Ovarian cancer Relapsed cancer treatment Immunotherapy Case report 
Anti-EGFR antibody monotherapy for colorectal cancer with severe hyperbilirubinemia: A case report
《World Journal of Gastrointestinal Oncology》2024年第2期557-562,共6页Toshiaki Tsurui Yuya Hirasawa Yutaro Kubota Kiyoshi Yoshimura Takuya Tsunoda 
BACKGROUND Hyperbilirubinemia with hepatic metastases is a common complication and a poor prognostic factor for colorectal cancer(CRC).Effective drainage is often im-possible before initiating systemic chemotherapy,ow...
关键词：Colorectal neoplasms PANITUMUMAB Chemotherapy HYPERBILIRUBINEMIA JAUNDICE Case report 
One-year outcomes of resveratrol supplement with aflibercept versus aflibercept monotherapy in wet agerelated macular degeneration被引量：1
《International Journal of Ophthalmology(English edition)》2023年第9期1496-1502,共7页Ioannis Datseris Nikolaos Bouratzis Charalambos Kotronis Iordanis Datseris Malvina-Efthimia Tzanidaki Alexandros Rouvas Nikolaos Gouliopoulos 
Supported by unrestricted Grant from Laboratoires Thea^(■),France.
AIM:To determine the one-year outcomes of resveratrol oral supplement in patients suffering from wet age-related macular degeneration(AMD).METHODS:Fifty naïve and previously untreated patients suffering from wet AMD,w...
关键词：wet age-related macular degeneration RESVERATROL AFLIBERCEPT Hospital Anxiety and Depression Scale contrast sensitivity 
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