ANDROGENETIC

作品数:14被引量:28H指数:2
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Current advances in haploid stem cells被引量:2
《Protein & Cell》2020年第1期23-33,共11页Tongtong Cui Zhikun Li Qi Zhou Wei Li 
supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDA16030400);the National Basic Research Program of China(Grant No.2014CB964800);the National Natural Science Foundation of China(Grant Nos.31621004,31422038);the National Key Research and Development Program(Grant No.2017YFA0103803);CAS Key Projects(Grant No.QYZDY-SSWSMC022,QYZDB-SSW-SMC002).
Diploidy is the typical genomic mode in all mammals.Haploid stem cells are artificial cell lines experimentally derived in vitro in the form of different types of stem cells,which combine the characteristics of haploi...
关键词:HAPLOIDY PARTHENOGENETIC ANDROGENETIC stem cells DIPLOIDIZATION functional genomics IMPRINTING 
Derivation of Haploid Neurons from Mouse Androgenetic Haploid Embryonic Stem Cells被引量:2
《Neuroscience Bulletin》2017年第3期361-364,共4页He Xu Chunmei Yue Ting Zhang Yuanyuan Li Ao Guo Jiaoyang Liao Gang Pei Jinsong Li Naihe Jing 
supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA01010201);the National Key Basic Research and Development Program of China(2015CB964500 and 2014CB964804);the National Natural Science Foundation of China(91219303,31430058,and 31401261)
Dear Editor,Haploid embryonic stem cells(ha ESCs)hold great potential for genetic screening and the analysis of recessive phenotypes.Several studies have recently reported the generation of mammalian ha ESCs through...
关键词:recessive haploid genomics screening embryonic manipulation pluripotent maintenance panel Mouse 
Derivation of androgenetic embryonic stem cells from m-carboxycinnamic acid bishydroxamide (CBHA) treated androgenetic embryos被引量:2
《Chinese Science Bulletin》2013年第23期2862-2868,共7页SHUAI Ling FENG ChunJing ZHANG HaiJiang GU Qi JIA YunDan WANG Liu ZHAO Xiao-Yang LIU ZhongHua ZHOU Qi 
supported by the National Key Basic Research Program of China(2012CB966500,2013CB-967100);the National Natural Science Foundation of China(31201112)
The androgenetic embyronic stem (aES) cells are useful models in studying the effects of imprinted genes on pluripotency maintaining and embryo development. The expression patterns of imprinted genes are significantly...
关键词:胚胎干细胞 雄性 ES细胞系 CAES 治疗 CB 印记基因 表达模式 
Haploid embryonic stem cells:an ideal tool for mammalian genetic analyses被引量:13
《Protein & Cell》2012年第11期806-810,共5页Linyu Shi Hui Yang Jinsong Li 
supported by grants from the Ministry of Science and Technology of China(No.2009CB941101 to J.L.);the "Strategic Priority Research Program" of the Chinese Academy of Sciences(No.XDA01010403 to J.L.).
Identification of the function of all genes in the mammalian genome is critical in understanding basic mechanisms of biology.However,the diploidy of mammalian somatic cells has greatly hindered efforts to elucidate th...
关键词:haploid embryonic stem cells parthenogenetic embryos androgenetic embryos genetic screening DIPLOID genomic imprinting 
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