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LSM14B coordinates protein component expression in the P-body and controls oocyte maturation
《Journal of Genetics and Genomics》2024年第1期48-60,共13页Huiru Zhang Tao Zhang Xiang Wan Chang Chen Shu Wang Dongdong Qin Lufan Li Luping Yu Xin Wu 
supported by the National Key R&D Program of China(2021YFC2700201 to X.W.);the National Natural Science Foundation of China(32070831,32270897 to X.W.).
The generation of mature and healthy oocytes is the most critical event in the entire female reproductive process,and the mechanisms regulating this process remain to be studied.Here,we demonstrate that Smith-like(LSM...
关键词：LSM14B P-BODY DDX6 MIl arrest Chromatin configuration 
Phosphorylation of ATF2 promotes odontoblastic differentiation via intrinsic HAT activity
《Journal of Genetics and Genomics》2023年第7期497-510,共14页Huanyan Zuo Yao Xiao Jiahao Han Yuxiu Lin Cheng Tian Shu Zhang Guohua Yuan Huan Liu Zhi Chen 
supported by the National Natural Science Foundation of China (No. 82071110 and No. 82230029) to Zhi Chen;the National Natural Science Foundation of China (No. 82071077 and No.82270948);“the Fundamental Research Funds for the Central Universities”;“The Young Top-notch Talent Cultivation Program of Hubei Province” to Huan Liu
Mouse dental papilla cells(mDPCs)are cranial neural crest-derived dental mesenchymal cells that give rise to dentin-secreting odontoblasts after the bell stage during odontogenesis.The odontoblastic differentiation of...
关键词：ODONTOBLAST Dental papilla Mesenchymal stem cells ATF Transcription factors Cell differentiation Chromatin accessibility 
Deciphering the chromatin spatial organization landscapes during BMMSC differentiation被引量：1
《Journal of Genetics and Genomics》2023年第4期264-275,共12页Zhaowei Teng Yun Zhu Da Lin Qinggang Hao Qiaoning Yue Xiaochao Yu Shuo Sun Lihong Jiang Sheng Lu 
supported in part by the National Natural Science Foundation of China,grant no.31960136;the Yunnan health training project for high-level talents;Yunnan Key Laboratory of Innovative Application of Traditional Chinese Medicine,grant no.202105AG070032;Kunming University of Science and Technology&the First People’s Hospital of Yunnan Province Joint Special Project on Medical Research,grant no.KUSTKH2022002Z;2021 Center of Yunnan Orthopedics and Sports Rehabilitation Clinical Medical Research,grant no.2022YJZXGK04;the 2023 Project of Yunnan Basic Research,grant no.202201AT070079 and 202201AT070285。
The differentiation imbalance in bone marrow mesenchymal stem cells(BMMSCs)is critical for the development of bone density diseases as the population ages.BMMSCs are precursor cells for osteoblasts and adipocytes;howe...
关键词：Bone marrow mesenchymal stem cells DIFFERENTIATION Hi-C ATAC-Seq Single nucleotide polymorphisms Genome-wide association studies 
SMOC:a smart model for open chromatin region prediction in rice genomes被引量：3
《Journal of Genetics and Genomics》2022年第5期514-517,共4页Weijun Guo Hanqing Liu Yifan Wang Pingxian Zhang Dongwei Li Tuoyu Liu Qian Zhang Liwen Yang Li Pu Jian Tian Xiaofeng Gu 
supported by grants from the National Natural Science Foundation of China (32130080);the Central Public-interest Scientific Institution Basal Research Fund (Y2020YJ09);the Agricultural Science and Technology Innovation Program (CAASZDRW202109);Agricultural Science and Technology Innovation Program (ASTIP-CAASZDRW202009);the Project of Hainan Yazhou Bay Seed Lab (B21HJ0223)
In eukaryotic genomes, the fundamental unit of chromatin is the nucleosome, which is composed of a histone octamer that contains two copies of each histone, H3, H2A, H2B, and H4 (Bell et al., 2011).Chromatin is wrappe...
关键词：SMART PREDICTION HELICAL 
Epigenome-Metabolome-Epigenome signaling cascade in cell biological processes被引量：2
《Journal of Genetics and Genomics》2022年第4期279-286,共8页Linpeng Li Keshi Chen Yi Wu Ge Xiang Xingguo Liu 
financially supported by the National Key Research and Development Program of China (2017YFA0106300);the Strategic Priority Research Program of the Chinese Academy of Sciences (XDA16030505);the National Natural Science Foundation projects of China (2017YFA0102900, 2019YFA09004500, 2017YFC1001602, 2016YFA0100300, 2018YFA0107100);the National Natural Science Foundation projects of China (92157202, 32025010, 31801168, 31900614, 31970709, 81901275, 32070729, 32100619, 32170747);the Key Research Program of Frontier Sciences, CAS (QYZDB-SSW-SMC001);International Cooperation Program (154144KYSB20200006);Guangdong Province Science and Technology Program (2020B1212060052, 2018A030313825, 2018GZR110103002, 2020A1515011200, 2020A1515010919, 2020A1515011410, 2021A1515012513);Guangzhou Science and Technology Program (201807010067, 202002030277, 202102021250, 202102020827, 202102080066), Open Research Program of Key Laboratory of Regenerative Biology, CAS (KLRB201907, KLRB202014);CAS Youth Innovation Promotion Association (to Y. W. and K. C.)
Cell fate determination as a fundamental question in cell biology has been extensively studied at different regulatory levels for many years.However,the mechanisms of multilevel regulation of cell fate determination r...
关键词：Cell biological processes CHROMATIN EPIGENOME METABOLOME Signaling cascade 
Freeze substitution Hi-C,a convenient and cost-effective method for capturing the natural 3D chromatin conformation from frozen samples
《Journal of Genetics and Genomics》2021年第3期237-247,共11页Wu Zheng Zhaoen Yang Xiaoyang Ge Yijia Feng Ye Wang Chengwei Liu Yanan Luan Kun Cai Serhii Vakal Feng You Wei Guo Wei Wang Zhenhua Feng Fuguang Li 
supported by funding from the National Natural Science Foundation of China,China(grants 31621005 and 31600093 to F.G.L.);the Young Elite Scientists Sponsorship Program by CAST(2019zx08010033-002-012 to Z.E.Y.);Central Public-interest Scientific Institution Basal Research Fund(Y2020PT13)。
Chromatin interactions functionally affect genome architecture and gene regulation,but to date,only fresh samples must be used in High-through chromosome conformation capture(Hi-C)to keep natural chromatin conformatio...
关键词：FS-Hi-C Frozen sample Chromosome conformation Drosophila melanogaster Gossypium hirsutum 
A single-cell atlas of mouse olfactory bulb chromatin accessibility
《Journal of Genetics and Genomics》2021年第2期147-162,共16页Yin Chen Xiangning Ding Shiyou Wang Peiwen Ding Zaoxu Xu Jiankang Li Mingyue Wang Rong Xiang Xiaoling Wang Haoyu Wang Qikai Feng Jiaying Qiu Feiyue Wang Zhen Fluang Xingliang Zhang Gen Tang Shengping Tang 
supported by Shenzhen Sanming Engineering Project(SZSM202011012);Shenzhen Innovation Science and Technology Committee(JCYJ20180228175358223);National Natural Science Foundation of China(31670742)。
Olfaction,the sense of smell,is a fundamental trait crucial to many species.The olfactory bulb(OB)plays pivotal roles in processing and transmitting odor information from the environment to the brain.The cellular hete...
关键词：scATAC-seq Mouse olfactory bulb Chromatin accessibility Transcription factor Endogenous retroviral elements Co-embedding analysis 
Tn5-FISH,a novel cytogenetic method to image chromatin interactions with sub-kilobase resolution
《Journal of Genetics and Genomics》2020年第12期727-734,共8页Jing Niu Xu Zhang Li Guipeng Pixi Yan Qing Yan Qionghai Dai Dayong Jin Xiaohua Shen Jichang Wang Michael QZhang Juntao Gao 
This work was supported in part by the State Key Research Development Program of China(2017YFA0505503);the National Natural Science Foundation of China(81890991 and 31671383);Beijing Advanced Innovation Center for Structural Bio logy,Tsinghua University(100300001);the fund from Foshan-Tsinghua Innovation Special Fund(FTISF,2019THFS0141)to J.G.,the National Natural Science Foundation of China(31871444);the program for Guangdong Introducing Innovative and Entrepreneurial Teams(2016ZT06S029)to J.W.;Australia China Science and Research Fund Joint Research Centre for POCT(ACSRF65827);Shenzhen Science and Technology Program(KQTD 20170810110913065)to D.J.
There is an increasing interest in understanding how three-dimensional(3D)organization of the genome is regulated.Different strategies have been employed to identify genome-wide chromatin interactions.However,due to c...
关键词：Fluorescencein situhybridization Chromatin interaction Cellular imaging Super resolution 
Decoding the plant genome: From epigenome to 3D organization
《Journal of Genetics and Genomics》2020年第8期425-434,共10页Weizhi Ouyang Zhilin Cao Dan Xiong Guoliang Li Xingwang Li 
supported by the National Natural Science Foundation of China(31771422);the National Key Research and Development Program of China(2016YFD0100904);the open funds of the National Key Laboratory of Crop Genetic Improvement(ZK201906)
The linear genome of eukaryotes is partitioned into diverse chromatin states and packaged into a threedimensional(3D)structure,which has functional implications in DNA replication,DNA repair,and transcriptional regula...
关键词：Plant genomics Epigenetic modification Chromatin three-dimensional structures Genomic methods 
ISWI ATP-dependent remodeling of nucleoplasmic u-speckles in the brain of Drosophila melanogaster
《Journal of Genetics and Genomics》2017年第2期85-94,共10页Luca Lo Piccolo Andrea Attardi Rosa Bonaccorso Lorenzo Li Greci Giorgio Giurato Antonia Maria Rita Ingrassia Maria Cristina Onorati 
supported by an Associazione Italiana Ricerca sul Cancro (AIRC) (MFAG-12779) fellowship;supported by My First Airc Grant (MFAG) number 12779 from AIRC to M.C.O
Heterogeneous nuclear ribonucleoproteins（hn RNPs） belong to the RNA-binding proteins family. They are involved in processing heterogeneous nuclear RNAs（hn RNAs） into mature m RNAs. These proteins participate in ev...
关键词：Omega speckles hnRNPs lncRNA Nuclear body Chromatin remodelers 
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