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The known,unknown,and unknown unknowns of cell-cell communication in planarian regeneration: 《Zoological Research》2023年第5期981-992,共12页Jia-Jia Chen Kai Lei; supported by the Westlake Education Foundation and National Natural Science Foundation of China (32122032 and 31970750 to K.L.)。; Planarians represent the most primitive bilateral triploblastic animals.Most planarian species exhibit mechanisms for whole-body regeneration,exemplified by the regeneration of their cephalic ganglion after complete e...; 关键词：PLANARIANS Stem cells REGENERATION Cell communication

Molecular systematics, population genetics and phylogeography on planarians(Platyhelminths: Turbellaria): A brief review of molecular markers被引量：2: 《Zoological Systematics》2019年第3期177-184,共8页Hecai Zhang Tiange Hu Changying Shi Guangwen Chen; supported by the National Natural Science Foundation of China(31702010,31471965); Due to their characteristics, such as powerful regeneration capability, high susceptibility to xenobiotics, wide distribution and weak dispersion ability, planarians are used as ideal test animals in several research ...; 关键词：PLANARIAN MOLECULAR marker MOLECULAR PHYLOGENY MOLECULAR taxonomy population genetics PHYLOGEOGRAPHY

Neoblast-enriched zinc finger protein FIR1 triggers local proliferation during planarian regeneration被引量：1: 《Protein & Cell》2019年第1期43-59,共17页Xiao-Shuai Han Chen Wang Fang-hao Guo Shuang Huang Yong-Wen Qin Xian-Xian Zhao Qing Jing; the National Key Research and Development Program of China(2017YFA0103700);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA16020903);the National Natural Science Foundation of China(91739301,91339205,and 31229002).; Regeneration,relying mainly on resident adult stem cells,is widespread.However,the mechanism by which stem cells initiate proliferation during this process in vivo is unclear.Using planarian as a model,we screened 46 ...; 关键词：LOCAL PROLIFERATION adult stem cells Dis3l2 wound recognition PLANARIANS Schmidtea mediterranea

Surprising Separation of Cannabinoid Physical Dependence and Withdrawal in an Invertebrate Model: 《Pharmacology & Pharmacy》2018年第12期489-502,共14页Wanhui Sheng Robert B. Raffa; Planarians have mammalian-like neurotransmitter systems and have been established as a novel in vivo model for neuropharmacology. In previous research, planarians that have been exposed to the cannabinoid receptor (CB...; 关键词：CANNABINOID Physical DEPENDENCE WITHDRAWAL PLANARIANS UV Light

Potential of a planarian model to study certain aspects of anti-Parkinsonism drugs: 《Advances in Parkinson's Disease》2013年第3期70-74,共5页Robert B. Raffa Jeff Danah Christopher S. Tallarida Carrie Zimmerman Grace Gill Steven J. Baron Scott M. Rawls; We previously created and investigated a planarian model for the study of drug action, abuse, physical dependence, receptor affinity, the toxicity of heavy metals in wastewater, and seizures. For the present pilot stu...; 关键词：L-DOPA BENSERAZIDE PLANARIANS

Amphetamine Conditioned Place Preference in Planarians: 《Journal of Behavioral and Brain Science》2013年第1期131-136,共6页Robert B. Raffa Sumira Shah Christopher S. Tallarida Scott M. Rawls; Meth- and other amphetamines currently present major drug-abuse concerns. However, the demonstration and study of abuse-related behaviors expressed in animal models is expensive and time-consuming. We previously repor...; 关键词：AMPHETAMINE Conditioned PLACE PREFERENCE Drug ABUSE PLANARIA

Isobolographic Method and Invertebrate (Planarian) Model for Evaluating Combinations of Waterways Pollutants: 《Pharmacology & Pharmacy》2012年第4期381-387,共7页Robert B. Raffa Deborah A. Gallo Christopher S. Tallarida Scott M. Rawls Ronald J. Tallarida; Agricultural, pharmaceutical, and other biologically active substances are emptied or leach into waterways and groundwater, where they can dose-relatedly cause pharmacologic or toxic effects on the resident or depende...; 关键词：COMBINATIONS Isobolographic Analysis Methods POLLUTANTS PLANARIANS

Development of a Behavioral and Imaging Model of Feeding in Planarians: 《Pharmacology & Pharmacy》2012年第3期364-367,共4页Robert B. Raffa Christopher S. Tallarida Shan R. Patel Scott M. Rawls Evgeny Krynetskiy; Excess weight is a major risk factor for type-2 diabetes, cardiovascular disease, and other comorbidities. Animal models of feeding provide insight into the problem and provide a means for the discovery and evaluation...; 关键词：FEEDING IMAGING FLUORESCENCE GFP PLANARIANS

Disruption of Drug Effects (Dopamine, Nicotine, Pilocarpine, κ-Opioid) in Planarians by UV Light: 《Pharmacology & Pharmacy》2012年第3期358-363,共6页Robert B. Raffa Christopher S. Tallarida Aruj Choudhry Nadia Sanni-Adam Sean McGonigle Michael Baron Zhuo L. Chen Scott M. Rawls Ronald J. Tallarida; Based on previous work, it has been hypothesized that the energetics of ultraviolet (UV) light disrupts effects induced by receptor-binding ligands. If this hypothesis is true, then UV light should (i) disrupt a broad...; 关键词：UV Light Drug-Receptor Interaction LOCOMOTOR Activity Seizure Physical Dependence PLANARIAN

Morphogenetic Action of Neurotransmitters on Regenerating Planarians—A Review: 《Biomedical and Environmental Sciences》1993年第4期327-347,共21页DAVIDVILLAR DAVIDJ.SCHAEFFER; Planarians can be used as invertebrate bioassays to evaluate the role of neurotransmitters on regenerating cells. The influence of the nervous system is crucial to regenerate a normal complete animal. The neurotrophic...; 关键词：Morphogenetic Action of Neurotransmitters on Regenerating Planarians A Review

PLANARIANS