Ministry of Science and Higher Education of the Russian Federation,Grant/Award Number:075-15-2024-536。
The prevention of blindness from glaucoma requires multiple treatments to lower intraocular pressure.Here,human contact lenses are modified with highly porous metal-organic frameworks with sustained release of brimonid...
This work was supported by grants from the National Natural Science Foundation of China(Grant No.81870681);the Natural Science Foundation of Hainan Province(Grant No.817364).
Background:The use of ocular hypotensive drugs has been reported to attenuate myopia progression.This study explores whether brimonidine can slow myopia progression in the guinea pig form-deprivation(FD)model.Methods:...
supported by the National Key Research and Development Program of China(2020YFA0112700);the State Key Program of National Natural Science Foundation of China(82030027);the Subject of Major Projects of National Natural Science Foundation of China(81790641);National Natural Science Foundation of China(81870630);Clinical Research Plan of SHDC(SHDC2020CR6029);the Scientific and Innovative Action Plan of Shanghai(19441900600);the Natural Science Foundation of Shanghai(19ZR1408300);the Science and Technology Commission of Shanghai Municipality(21Y11909900);Shanghai Municipal Health Commission(202240316).
Glaucoma is the leading cause of irreversible blindness,affecting 111 million people by 2040 worldwide.Intraocular pressure(IOP)is the only controllable risk factor for the disease and current treatment options seek t...
supported by grants from the National Natural Science Foundation of China(Grant No.81870681);the Natural Science Foundation of Hainan Province(Grant No.817364).
Background:The use of ocular hypotensive drugs has been reported to attenuate myopia progression.This study explores whether brimonidine can slow myopia progression in the guinea pig form-deprivation(FD)model.Methods:...
supported,in part,by the National Institutes of Health(R01EY024072)(HY);the Fundamental Research Funds for the Central Universities(Grant No.3332019100,2019PT320028)(BL).
Chitosan is a nature-based polymer with low toxicity,excellent biocompatibility and biodegradability.However,the intractable solubility of chitosan in water and most conventional solvents hampers its biomedical applic...
AIM:To evaluate the mechanism of which brimonidine tartrate 0.15%causes clinical hypersensitivity.METHODS:A prospective case-control study comparing 8 glaucoma patients with clinical hypersensitivity to brimonidine to...
The importance of 24-hour intraocular pressure(IOP)assessment has increasingly being recognized in recent years(1-4).In cardiology,24-hour blood pressure monitoring is widely employed to accurately characterize a pati...
Supported by the National Natural Science Foundation of China(No.81400428);Science and Technology Commission of Shanghai Municipality(No.134119b1600)
AIM: To investigate the intraocular pressure(IOP) of adult guinea pig eyes with rebound tonometry(RBT),and assess the effects of four distinctive topical IOP reducing medications including Carteolol,Brimonidine,B...
The treatment of glaucoma in and around pregnancy offers the unique challenge of balancing the risk of vision loss to the mother as against the potential harm to the fetus or newborn. Most anti-glaucoma drugs(i.e.bet...
Background:To test and compare in a masked fashion the efficacy of using a parasympathomimetic drug(3%carbachol)and an alpha-2 agonist(0.2%brimonidine)in both combined and separate forms to create optically beneficial...