BASOPHILS

作品数:14被引量:41H指数:4
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相关领域:医药卫生更多>>
相关作者:郑东淑张秋贵张慧云罗鸿何韶衡更多>>
相关机构:广东医学院附属医院福建医科大学附属厦门市第一医院青岛大学医学院附属医院华中科技大学更多>>
相关期刊:《Advances in Bioscience and Biotechnology》《Chinese Herbal Medicines》《Cellular & Molecular Immunology》《Acta Pharmacologica Sinica》更多>>
相关基金:国家自然科学基金中国博士后科学基金国家重点基础研究发展计划“十一五”国家科技支撑计划更多>>
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Discovery of highly immunogenic spleen-resident FCGR3^(+)CD103^(+)cDC1s differentiated by IL-33-primed ST2^(+)basophils
《Cellular & Molecular Immunology》2023年第7期820-834,共15页Myeong-Ho Kang JungHyub Hong Jinjoo Lee Min-Suk Cha Sangho Lee Hye-Young Kim Sang-Jun Ha Yong Taik Lim Yong-Soo Bae 
the National Research Foundation of Korea(SRC-2017R1A5A1014560). This work was supported by grants from the National Research Foundation of Korea(SRC-2017R1A5A1014560)。
Recombinant interleukin-33(IL-33)inhibits tumor growth,but the detailed immunological mechanism is still unknown.IL-33-mediated tumor suppression did not occur in Batf3^(−/−)mice,indicating that conventional type 1 de...
关键词:Recombinant interleukin-33(IL-33) Highly immunogenic Spleen residency FCGR3^(+)CD103^(+)cDC1s ST2^(+)basophils Antitumor immunity 
Basophils orchestrate kidney fibrosis被引量:1
《Cell Research》2022年第8期713-714,共2页Camille Chauvin Jagadeesh Bayry 
Jagadeesh Bayry,email:bayry@iitpkd.ac.in。
Basophils,though representing a minor population of leukocytes,have diverse roles in various pathophysiologies.A recent report provides an additional evidence on the pathogenic role of basophils in promoting kidney fi...
关键词:hence IMMUNITY diverse 
Basophils as a potential therapeutic target in cancer被引量:1
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2021年第12期971-984,共14页Jicheng ZHANG Hanlin YIN Qiangda CHEN Guochao ZHAO Wenhui LOU Wenchuan WU Ning PU 
supported by the Shanghai Sailing Program(No.21YF1407100);the China Postdoctoral Science Foundation(No.2021M690037);the National Natural Science Foundation of China(Nos.82103409 and 81773068);the National Key R&D Program of China(No.2019YFC1315902)。
Basophils,which are considered as redundant relatives of mast cells and the rarest granulocytes in peripheral circulation,have been neglected by researchers in the past decades.Previous studies have revealed their vit...
关键词:BASOPHIL CANCER CYTOKINE CHEMOKINE Tumor microenvironment 
Autoimmune pancreatitis and pancreatic cancer:Epidemiological aspects and immunological considerations被引量:4
《World Journal of Gastroenterology》2021年第25期3825-3836,共12页Dimitri Poddighe 
Ordinary chronic pancreatitis is a well-known risk factor for pancreatic cancer,whereas such an association with autoimmune pancreatitis(AIP)is widely debated.Due to the rarity of the latter disorder,there are few spe...
关键词:Autoimmune pancreatitis Chronic pancreatitis Pancreatic cancer Immunoglobulin G4-related disease Epidemiology IMMUNOLOGY BASOPHILS MACROPHAGES Th2 cells Systemic lupus erythematosus 
New insights into roles of basophils in initiating T helper type 2 immunity
《Chinese Herbal Medicines》2020年第1期14-18,共5页Tian-xiang Ma Yuan Gao 
supported by the National Natural Science Foundation of China(NSFC)(No.81873066).
Allergic diseases,mainly mediated by T helper type 2(Th2)immunity,have become a worldwide public health problem.Traditional Chinese medicine(TCM)has long been used in treating and preventing allergic symptoms.As the n...
关键词:BASOPHILS IL-4 IMMUNE response T HELPER TYPE 2 traditional Chinese MEDICINES 
Effect of brimonidine tartrate on basophil activation in glaucoma patients被引量:1
《International Journal of Ophthalmology(English edition)》2020年第3期509-512,共4页Eldar Rosenfeld Dana Barequet Gilad Rabina Sheila Langier Moshe Lazar Gabi Shemesh Shimon Kurtz Shmuel Kivity 
AIM:To evaluate the mechanism of which brimonidine tartrate 0.15%causes clinical hypersensitivity.METHODS:A prospective case-control study comparing 8 glaucoma patients with clinical hypersensitivity to brimonidine to...
关键词:GLAUCOMA ALLERGY HYPERSENSITIVITY BRIMONIDINE TIMOLOL BASOPHILS 
NOD2 and TLR2 ligands trigger the activation of basophils and eosinophils by interacting with dermal fibroblasts in atopic dermatitis-like skin inflammation被引量:8
《Cellular & Molecular Immunology》2016年第4期535-550,共16页Delong Jiao Chun-Kwok Wong Huai-Na Qiu Jie Dong Zhe Cai Man Chu Kam-Lun Hon Miranda Sin-Man Tsang Christopher Wai-Kei Lam 
The skin of patients with atopic dermatitis (AD) has a unique predisposition for colonization by Staphylococcus aureus (S. aureus), which contributes to the inflammation and grim prognosis of AD. Although the mech...
关键词:atopic dermatitis basophils  eosinophils NOD2 TLR2 
The Cbl family of ubiquitin ligases regulates FcεRI expression and mast cell activation
《Advances in Bioscience and Biotechnology》2013年第12期1063-1072,共10页Rosa Molfetta Francesca Gasparrini Angela Santoni Rossella Paolini 
Antigen interaction with specific IgE bound to the high-affinity Fc receptor for IgE, constitutively expressed on the cell-surface of mast cells, generates signals that cause a shift in the resting state equilibrium o...
关键词:MAST Cells BASOPHILS FCΕRI Negative Regulation CBL PROTEINS UBIQUITINATION 
Mast cells and basophils are essential for allergies: mechanisms of allergic inflammation and a proposed procedure for diagnosis被引量:16
《Acta Pharmacologica Sinica》2013年第10期1270-1283,共14页Shao-heng HE Hui-yun ZHANG Xiao-ning ZENG Dong CHEN Ping-chang YANG 
This project was supported through grants from the Major State Basic Research Program of China (973 Program, No 2013CB530500); the National Natural Science Foundation of China (No 81030054, 81172836, 81241135, and 81060250); and the Key Project of the Natural Science Foundation of Jiangsu Province, China (No BK2010020).
The current definition of allergy is a group of IgE-mediated diseases. However, a large portion of patients with clinical manifestations of allergies do not exhibit elevated serum levels of IgE (slgEs). In this arti...
关键词:ALLERGY mast cell BASOPHIL IGE IgG pseudo-allergic reaction specific allergen challenge test basophil activation test 
Inflammatory Cytokine Secretion Status of Bone Marrow Cells and Clinical Significance in Immune-related Hematocytopenia被引量:3
《国际感染病学(电子版)》2013年第3期102-109,共8页Li-fei Sun Qiang-qiang Wu Zhi-hong Sun Bing Han Hong-feng Hao Gui-chen Wang Ming Li Jin-biao Zhang 
Objective To observe the expression of inlfammatory molecules in bone marrow immune cells of patients with immune-related hematocytopenia (IRH), and to investigate the immune mechanism and clinical signiifcance of the...
关键词:Immune-related hematocytopenia BASOPHILS EOSINOPHILS Anti-human IgG immunoglobulin IL-17AL IL-17RA Immune molecules 
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