the National Research Foundation of Korea(SRC-2017R1A5A1014560). This work was supported by grants from the National Research Foundation of Korea(SRC-2017R1A5A1014560)。
Recombinant interleukin-33(IL-33)inhibits tumor growth,but the detailed immunological mechanism is still unknown.IL-33-mediated tumor suppression did not occur in Batf3^(−/−)mice,indicating that conventional type 1 de...
Basophils,though representing a minor population of leukocytes,have diverse roles in various pathophysiologies.A recent report provides an additional evidence on the pathogenic role of basophils in promoting kidney fi...
supported by the Shanghai Sailing Program(No.21YF1407100);the China Postdoctoral Science Foundation(No.2021M690037);the National Natural Science Foundation of China(Nos.82103409 and 81773068);the National Key R&D Program of China(No.2019YFC1315902)。
Basophils,which are considered as redundant relatives of mast cells and the rarest granulocytes in peripheral circulation,have been neglected by researchers in the past decades.Previous studies have revealed their vit...
Ordinary chronic pancreatitis is a well-known risk factor for pancreatic cancer,whereas such an association with autoimmune pancreatitis(AIP)is widely debated.Due to the rarity of the latter disorder,there are few spe...
supported by the National Natural Science Foundation of China(NSFC)(No.81873066).
Allergic diseases,mainly mediated by T helper type 2(Th2)immunity,have become a worldwide public health problem.Traditional Chinese medicine(TCM)has long been used in treating and preventing allergic symptoms.As the n...
AIM:To evaluate the mechanism of which brimonidine tartrate 0.15%causes clinical hypersensitivity.METHODS:A prospective case-control study comparing 8 glaucoma patients with clinical hypersensitivity to brimonidine to...
The skin of patients with atopic dermatitis (AD) has a unique predisposition for colonization by Staphylococcus aureus (S. aureus), which contributes to the inflammation and grim prognosis of AD. Although the mech...
Antigen interaction with specific IgE bound to the high-affinity Fc receptor for IgE, constitutively expressed on the cell-surface of mast cells, generates signals that cause a shift in the resting state equilibrium o...
This project was supported through grants from the Major State Basic Research Program of China (973 Program, No 2013CB530500); the National Natural Science Foundation of China (No 81030054, 81172836, 81241135, and 81060250); and the Key Project of the Natural Science Foundation of Jiangsu Province, China (No BK2010020).
The current definition of allergy is a group of IgE-mediated diseases. However, a large portion of patients with clinical manifestations of allergies do not exhibit elevated serum levels of IgE (slgEs). In this arti...
Objective To observe the expression of inlfammatory molecules in bone marrow immune cells of patients with immune-related hematocytopenia (IRH), and to investigate the immune mechanism and clinical signiifcance of the...