N-ACETYLATION

作品数:4被引量:4H指数:1
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相关领域:医药卫生理学更多>>
相关期刊:《Chinese Medical Journal》《Neural Regeneration Research》《Chinese Chemical Letters》《Acta Pharmaceutica Sinica B》更多>>
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Navigating the dynamic landscape of alpha-synuclein morphology: a review of the physiologically relevant tetrameric conformation被引量:1
《Neural Regeneration Research》2020年第3期407-415,共9页Heather R.Lucas Ricardo D.Fernández 
supported in part by Award No.18-7(to HRL)from the Commonwealth of Virginia’s Alzheimer’s and Related Diseases Research Award Fund,administered by the Virginia Center on Aging
N-acetylatedα-synuclein(αSyn)has long been established as an intrinsically disordered protein associated with a dysfunctional role in Parkinson’s disease.In recent years,a physiologically relevant,higher order conf...
关键词:ALPHA-SYNUCLEIN amyloid FIBRILS intrinsically disordered PROTEIN MULTIMER N-ACETYLATION oligomer Parkinson’s disease PROTEIN folding PROTEIN structure TETRAMER 
Arylamine N-acetyltransferase 2 genotype-dependent N-acetylation of isoniazid in cryopreserved human hepatocytes被引量:3
《Acta Pharmaceutica Sinica B》2017年第4期517-522,共6页Mark A.Doll Raúl A.Salazar-González Srineil Bodduluri David W.Hein 
supported by National Institutes of Health grants R25-CA134283 and P20-GM113226(USA)
Cryopreserved human hepatocytes were used to investigate the role of arylamine N-acetyltransferase 2 (NAT2; EC 2.3.1.5) polymorphism on the N-acetylation of isoniazid (INH). NAT2 genotype was determined by Taqman alle...
关键词:ISONIAZID N-Acetyltransferase 2 Acetylation polymorphism Human hepatocytes GENOTYPE PHENOTYPE 
First Application of Optically Active trans-1,2-Bis(2- aminophenyl)cyclopentane for Asymmetric Reaction: Enantioselective N-Acetylation of Secondary Alkyl Amines
《Chinese Chemical Letters》2001年第1期1-4,共4页
关键词:First Application of Optically Active trans-1 2-Bis ENANTIOSELECTIVE N-Acetylation of Secondary Alkyl Amines 
Relationship between metabolic phenotype of N-acetylation and bladder cancer
《Chinese Medical Journal》2000年第4期15-17,共3页崔唏 郭瑞臣 徐祉顺 王本杰 李朝武 
To study the relationship between metabolic phenotype of acetylation and bladder cancer Methods Totally 203 healthy volunteers and 67 patients with bladder cancer were investigated with caffeine as a metabolic probe...
关键词:N  acetylation phenotype POLYMORPHISM bladder cancer CAFFEINE 
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