FIBRILS

作品数:37被引量:31H指数:3
导出分析报告
相关领域:医药卫生理学更多>>
相关作者:柯莎朱笠江轶李辉周筠梅更多>>
相关机构:中国科学院大学中国科学院清华大学更多>>
相关期刊:《Science Bulletin》《Journal of Analytical Sciences, Methods and Instrumentation》《Light(Science & Applications)》《Natural Science》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金湖北省自然科学基金更多>>
-

检索结果分析

结果分析中...
条 记 录,以下是1-10
视图:
排序:
Cellulose Elementary Fibrils as Deagglomerated Binder for High-Mass-Loading Lithium Battery Electrodes
《Nano-Micro Letters》2025年第5期281-296,共16页Young-Kuk Hong Jung-Hui Kim Nag-Young Kim Kyeong-Seok Oh Hong-I Kim Seokhyeon Ryu Yumi Ko Ji-Young Kim Kwon-Hyung Lee Sang-Young Lee 
supported by the Institute of Civil Military Technology Cooperation funded by the Defense Acquisition Program Administration and Ministry of Trade,Industry and Energy of Korean government under grant No 23-CM-AI-08.
Amidst the ever-growing interest in high-mass-loading Li battery electrodes,a persistent challenge has been the insufficient continuity of their ion/electron conduction pathways.Here,we propose cellulose elementary fi...
关键词:Cellulose elementary fibrils Deagglomeration Electrode binders Lithium batteries High-mass-loading 
α-Synuclein pathology from the body to the brain:so many seeds so close to the central soil被引量:1
《Neural Regeneration Research》2024年第7期1463-1472,共10页Yunying Yang Zhentao Zhang 
supported by the National Natural Science Foundation of China,Nos.82271447,81771382;the National Key Research and Development Program of China,No.2019 YFE0115900;the"New 20 Terms of Universities in Jinan,No.202228022 (all to ZZ)。
α-Synuclein is a protein that mainly exists in the presynaptic terminals.Abnormal folding and accumulation of α-synuclein are found in several neurodegenerative diseases,including Parkinson’s disease.Aggregated and...
关键词:aggregation autonomic nervous system barrier receptors body fluid circulation in situ generation Parkinson’s disease PHOSPHORYLATION propagation SYNUCLEINOPATHIES Α-SYNUCLEIN α-synuclein fibrils 
Congophilic fibrils in the glomeruli with polyclonal immunoglobulin gamma staining-another cause for diagnostic overlap:A case report
《World Journal of Clinical Cases》2024年第17期3200-3205,共6页Maria Bernadette Che-Ying Chow Lucas Bushrow Irmeen Siddiqui April Chiu Mirza Hamirani Anjali A Satoskar 
BACKGROUND Glomerulopathy with fibrillary deposits is not uncommon in routine nephropathology practice,with amyloidosis and fibrillary glomerulonephritis being the two most frequently encountered entities.Renal amyloi...
关键词:Heavy and light chain amyloid Fibrillary glomerulonephritis DNAJB9 Serum immunofixation Protein electrophoresis Mass spectrometry Congo red Case report 
Benzothiazole-endoperoxide conjugates protect PC12 cells againstβ-amyloid-induced cell death via singlet oxygen mediated oxidative detoxification of fibrils
《Smart Molecules》2024年第2期111-118,共8页Hao Wu Lei Wang Xiao Qian Wanwan Wang Yu Si Rensong Sun Engin U.Akkaya 
supported by the National Natural Science Foundation of China(22178048,22007008);the LiaoNing Revitalization Talents Program(XLYC1902001,XLYC1907021);the Fundamental Research Funds for the Central Universities(DUT18RC(3)062,DUT19RC(3)009,DUT23YG120).
Metastable endoperoxides with beta-amyloid fibrils targeting benzothiazole moieties were designed and synthesized.Singlet oxygen released from these endoperoxides by thermal cycloreversion reaction was shown to cause ...
关键词:β-amyloid protein Alzheimer's disease BENZOTHIAZOLE ENDOPEROXIDES singlet oxygen 
α-Synuclein oligomers and fibrils:partners in crime in synucleinopathies被引量:1
《Neural Regeneration Research》2023年第11期2332-2342,共11页Alessandra Bigi Roberta Cascella Cristina Cecchi 
University of Florence(Fondi Ateneo to RC and CC);Ministry of Education,Universities and Research of Italy(Progetto Dipartimento di Eccellenza to CC)。
The misfolding and aggregation of a-synuclein is the general hallmark of a group of devastating neurodegenerative pathologies referred to as synucleinopathies,such as Parkinson’s disease,dementia with Lewy bodies,and...
关键词:amyloid aggregation neurodegeneration Parkinson’s disease protein aggregation protein misfolding 
Mid-infrared chemical imaging of intracellular tau fibrils using fluorescence-guided computational photothermal microscopy
《Light(Science & Applications)》2023年第7期1354-1369,共16页Jian Zhao Lulu Jiang Alex Matlock Yihong Xu Jiabei Zhu Hongbo Zhu Lei Tian Benjamin Wolozin Ji-xin Cheng 
supported by the National Institute of General Medical Sciences(R35GM136223);a grant from Daylight Solutions,and a grant(2023-321163);the Chan Zuckerberg Initiative Donor-Advised Fund at the Silicon Valley Community Foundation.
Amyloid proteins are associated with a broad spectrum of neurodegenerative diseases.However,it remains a grand challenge to extract molecular structure information from intracellular amyloid proteins in their native c...
关键词:TAU AMYLOID chemical 
Nanocomposites Facilitate the Removal of AβFibrils for Neuroprotection
《Chemical Research in Chinese Universities》2022年第2期522-528,共7页CHAI Jingshan LI Qiushi ZHAO Yu LIU Yang 
supported by the National Key Research and Development Programs of China(No.2018YFA0209700);the Fund of the Frontiers Science Center for New Organic Matter,Nankai University,China(No.63181206);the National Natural Science Foundation of China(Nos.22077073,22007051);the Fundamental Research Funds for the Central Universities,Nankai University,China(No.63206015);the China Postdoctoral Science Foundation (No.2019M660975).
Accumulation of β-amyloid(Aβ) fibrils in the brain is one of the main culprits in Alzheimer’s disease(AD) progression, which initiates the neuronal damage and subsequent neurodegeneration. Various anti-Aβ agents h...
关键词:Alzheimer’s disease Aβfibril Nanocomposite Hydrogen-bonding interaction MICROGLIA 
Aggregation properties of a therapeutic peptide for rheumatoid arthritis:A spectroscopic and molecular dynamics study
《ChemPhysMater》2022年第1期62-70,共9页Rita Cimino Marco Savioli Noemi Ferrante Carrante Ernesto Placidi Hilda Garay-Perez Matilde López-Abad Alexis Musacchio Lasa Maria Del Carmen Domínguez-Horta Emanuela Gatto Francesca Cavalieri Gianfranco Bocchinfuso Mariano Venanzi 
This project received funding from the European Union Horizon 2020 Research and Innovation Program under the Marie Skłodowska-Curie grant agreement no.872233(“PEPSA-MATE”).GB acknowledges CINECA and the EU-PRACE program for the CPU time.FC acknowledges the funding received as an award of an RMIT senior vice chancellor fel-lowship.
The biological properties of therapeutic peptides,such as their pharmacokinetics and pharmacodynamics,are correlated with their structure and aggregation properties.Herein,we studied the aggregation properties of a th...
关键词:Molecular dynamics of peptide oligomers Peptide aggregation Peptide fibrils Peptide nanostructures Therapeutic peptides Treatment of rheumatoid arthritis 
Self-assembled nanochaperones enable the disaggregation of amyloid insulin fibrils被引量:1
《Science China Chemistry》2022年第2期353-362,共10页Hui Wang Ang Li Menglin Yang Yu Zhao Linqi Shi Rujiang Ma 
supported by the National Natural Science Foundation of China(51773099,51933006)。
The deposition of highly ordered amyloid fibrils is recognized as a hallmark of amyloidosis diseases such as Alzheimer’s disease and Parkinson’s disease.Disaggregating the amyloid fibrils is considered as one of the...
关键词:amyloid fibrils INSULIN nanochaperones DISAGGREGATION 
Alpha-synuclein preformed fibrils:a tool to understand Parkinson’s disease and develop disease modifying therapy
《Neural Regeneration Research》2021年第11期2219-2221,共3页Piotr Chmielarz Andrii Domanskyi 
supported by grants from the Academy of Finland#293392,#319195;Päivikki and Sakari Sohlberg Foundation(to AD);Polish National Science Centre grant 2019/35/D/NZ7/03200-Sonata 15(to PC).
Parkinson’s disease(PD)is the second most common neurodegenerative disorder characterized by multiple motor and nonmotor symptoms,which include,among others,constipation,sleep disturbance,bradykinesia,gait and balanc...
关键词:degeneration Alpha driving 
检索报告 对象比较 聚类工具 使用帮助 返回顶部