supported by the National Natural Science Foundation of China(81774319).
Objective:To evaluate the therapeutic effects of Epimedium brevicornu Maxim.(EBM,Yin Yang Huo)on breast cancer using network pharmacology and in vitro validation.It also aimed to explore the novel targets and mechanis...
supported in part by the Scientific Research Projects of Hubei Health Commission(WJ2023M119);Hubei Province Research Innovation Team Project(T2021022).
Background:Studying the potential targets and mechanisms of Epimedium for anti-diabetic testicular injury using network pharmacology,molecular docking,and cell experiments.Methods:Acquisition of major components and t...
This research was supported by the Natural Science Foundation of Sichuan Province(No.2023NSFSC1282);the National General Cultivation Project of China West Normal University(No.19B029);Youth Foundation Specialization of West China Normal University(No.22KB004).
Mediated by pollenflow,natural hybridization is deemed a crucial factor that propels speciation infloral plants.Despite the fact that the diversity of Epimedium species is concentrated mainly in Southwestern China,the p...
supported by The National Key Research and Development Program of China(2021YFD1300301/2021YFD1300303);The Special Basic Research Fund for Central Public Research Institutes(2021-YWF-ZYSQ-06);The Agricultural Science and Technology Innovation Program(ASTIP)in CAAS and its key projects(CAAS-ZDRW202111);The Chinese Academy of Agricultural Science and Technology Innovation Project(ASTIP-IAS-12)。
Background Growth-promoting antibiotics have been banned by law in the livestock and poultry breeding industry in many countries.Various alternatives to antibiotics have been investigated for using in livestock.Epimed...
This work was supported by the National Natural Science Foundation of China(No.81673787);the Science and Technology Plan Project of Xi'an City(No.2019114813YX003SF036-3);Scientific research project of Xi'an Health Committee(No.2021yb43).
Curculigo orchioides(CUR)and Epimedium(EPI)are traditional Chinese medicines with estrogen-like biological activity,called Xianmao and Xianlingpi(Er-xian)in Chinese.However,whether Er-xian exerts protective effects on...
This work was supported by grants from the CAMS Innovation Fund for Medical Sciences(CIFMS)(2021-I2M-1-031 and 2017-I2M-3-013);the National Natural Science Foundation of China(31570306 and 81473302).
Epimedium pubescens Maxim.is a well-known traditional Chinese medicinal herb with flavonol glycosides as the major pharmaceutically active compounds.UDP-glycosyltransferases(UGTs)are a group of enzymes responsible for...
supported by the National Natural Science Foundation of China(Nos.81673548 and U20A20407);Liaoning Revitalization Talents Program(No.XLYC1902119).
Four new prenylflavonoid glycosides,namely koreanoside H-K(1-4),together with eleven known ones(5-15)were isolated from the leaves of Epimedium koreanum Nakai.Their structures were elucidated by ID NMR,2D NMR,HR-ESI-M...
supported by the National Natural Science Foundation of China (32071675,31670346);Biological Resources Programme,Chinese Academy of Sciences(KFJ-BRP-007-16);the Application Foundation Frontier Project of Wuhan Science and Technology Bureau (2019020701011435);the National Science and Technology Infrastructure program of China-compilation of Ex Situ Cultivated Flora of Botanical Garden (2015FY210100);the Key Scientific Research Talents Project of Wuhan Botanical Garden,Chinese Academy of Sciences (Y855281A05);Key Area R&D Project of Guangdong Province (2020B020221001);Guangdong Provincial Special Fund For Modern Agriculture Industry Technology Innovation Teams,China (2020KJ148)
Epimedii Herba is a commonly used traditional Chinese herbal medicine.Five Epimedium species are included in Chinese Pharmacopoeia and most species of Epimedium are used as Epimedii Herba in practical application.Howe...
Incubation Project on State Key Laboratory of Biological Resources and Ecological Environment of Qinba Areas,China(SLGPT2019KF04-04);and the ERDF through the COMPETE2020-Programa Operacional Competitividade e Internacionalização(POCI),Portugal。
OBJECTIVE Epimedium is rich in a variety of beneficial active ingredients,and has been widely used in the ethnopharmacological practices,however,its biotransformation in gastrointestinal digestions remain unclear.This...
This work was supported by National key research and development program of China(122300411149).
Background:Eucommia ulmoides and Epimedium brevicornu Maxim are widely used for the treatment of osteoporosis,but the mechanism of action for these plant extracts has not been elucidated.Methods:We used data mining an...