ANALOGUES

作品数:350被引量:463H指数:9
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相关机构:北京大学沈阳药科大学北京医科大学辽宁大学更多>>
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  • 期刊=Science China Chemistryx
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Ring-opening metathesis polymerization of cyclopropene derivatives towards polyolefin elastomer analogues
《Science China Chemistry》2022年第11期2182-2187,共6页Jing Bai Yu Wang Wei You 
supported by the National Natural Science Foundation of China(22001254);。
Polyolefin elastomers(POEs) are important reprocessable industrial materials with high strain-recovery performance. Traditional POEs are prepared from transition-metal-catalyzed polymerization of ethylene and α-olefi...
关键词:CYCLOPROPENES ring-opening metathesis polymerization polyolefin elastomers alkyl substituents 
Designing anticancer combretastatin A-4 analogues with aggregation-induced emission characteristics被引量:1
《Science China Chemistry》2022年第4期694-698,共5页Rucheng Zhao Yusheng Wu Yuequn Zhang Jiabao Ling Xinxin Liu Jiaqi Xiang Xiangchao Zeng Tianfeng Chen 
supported by the National Key R&D Programs of China(2017YFC1103603);the National Natural Science Foundation of China(21877049,32171296);Guangdong Natural Science Foundation(2020B1515120043);the Innovation Team Project in Guangdong Colleges and Universities(2019KCXTD008);K.C.Wong Education Foundation。
Herein a series of combretastatin A-4(CA-4)analogues with aggregation-induced emission characteristics(compounds a1-a19)were rationally designed and synthesized.The research results showed that the mechanism of AIE of...
关键词:combretastatin A-4 analogues ANTICANCER AIE CARBAZOLE FLUORENE 
Origin of enhanced stability in thiocyanate substituted α-FAPbI3 analogues
《Science China Chemistry》2019年第7期866-874,共9页Zhuo Xu Ming Chen Shengzhong (Frank) Liu 
supported by the National Key Research and Development Program of China(2017YFA0204800/2016YFA0202403);the Fundamental Research Funds for the Central Universities(2018CBLZ006);the National Natural Science Foundation of China(61604091,61674098);the 111 Project(B14041);the Changjiang Scholar and Innovative Research Team(IRT_14R33);the Chinese National 1000 Talents Plan program(1110010341);the China Postdoctoral Science foundation(2018M633455)
In the past few years,hybrid perovskites have emerged as the most promising photovoltaic materials due to their excellent optoelectronic properties,and easy fabrication methods.However,the long-term stability is still...
关键词:THIOCYANATE STABILITY formamidinium perovskites density-functional THEORY 
Synthesis of photolabile dUTP analogues and their enzymatic incorporation for DNA labeling
《Science China Chemistry》2014年第2期322-328,共7页WU JunZhou WANG Jie TANG XinJing 
supported by the National Natural Science Foundation of China(21072015);the National Basic Research Program of China(973 Program,2012CB720600);the Program for New Century Excellent Talents in University(NCET-10-0203);the State Key Laboratory of Drug Research(SIMM1106KF-15)
Two new photolabile nucleotide analogues with furan-fused deoxyuridine were synthesized through Sonogashira coupling.Their enzymatic incorporation into DNA was evaluated with two DNA polymerases(Taq and Deep vent exo-...
关键词:photolabile nucleotides enzymatic incorporation nucleotide analogues fluorescent labeling 
Design, synthesis, insecticidal evaluation and molecular docking studies of cis-nitenpyram analogues bearing diglycine esters被引量:2
《Science China Chemistry》2013年第2期159-168,共10页CHEN YanXia SUN ChuanWen WEN XiaXia ZHANG WangGeng 
supported by the National Natural Science Foundation of China (21042010, 21102092 and 30870560);the Key Scientific "Twelfth Five-Year" National Technology Support Program (2011BAE06B01-17);the Key Project of Science and Technology Commission of Shanghai (105405503400);the Innovation Project of Shanghai Education Commission (12YZ078);the Leading Academic Discipline Project of Shanghai Normal University (DZL808);Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Normal University (07dz22303)
Based on the strategies of receptor structure-guided neonicotinoid design, a series of novel cis-nitenpyram analogues bearing diglycine esters were designed and synthesized. Preliminary bioassays indicated that the in...
关键词:cis-nitenpyram analogues hydrogen bonds diglycine ester synthesis insecticidal activity molecular docking nAChRs peptide bond 
Studies on the synthesis,pungency and anti-biofouling performance of capsaicin analogues被引量:4
《Science China Chemistry》2012年第3期435-442,共8页PENG BiXian WANG JunLian PENG ZhengHong ZHOU ShengZe WANG FengQi JI YongLiang YE ZhangJi ZHOU XiangFeng LIN Tong ZHANG XiaoBin 
supported by the National HighTechnology Research and Development Program of China (863 Program 2010AA065104)
Ten capsaicin analogues were synthesized and their pungency degrees were determined through Scoville Organoleptic Test. The relationship between the structure and pungency degree of these capsaicin analogues was discu...
关键词:capsaicin analogues PUNGENCY relationship between structure and pungency degree anti-biofouling performance 
Synthesis and biological evaluation of 8-substituted and deglucuronidated scutellarin and baicalin analogues as antioxidant responsive element activators被引量:3
《Science China Chemistry》2011年第10期1565-1575,共11页YANG Ping KONG XiangZhen CHENG ChangMei LI ChangYan YANG XiaoMing ZHAO Xing'E 
Flavonoids are important bioactive dietary compounds, which are proved to be antioxidant responsive element (ARE) activators to defend against electrophilic toxicants and oxidative stress. The activators induce ARE ge...
关键词:SCUTELLARIN BAICALIN ARE activator Nrf2 NQO1 
Synthesis of (S)-(+)-tylophorine and its seco analogues using free radical reaction
《Science China Chemistry》2009年第9期1288-1299,共12页WANG ZiWen WANG KaiLiang CUI MingBo WANG QingMin 
Supported by the National Natural Science Foundation of China (Grant No 20872072);the Key Project of Chinese Ministry of Education (Grant No 106046)
The synthesis of (S)-(+)-tylophorine and its seco analogues has been accomplished by using free radical reaction. -N-(2,3,6,7-Tetramethoxyphenanthren-9-ylmethyl)-2-bromomethylpyrrolidine (7) and -N-(2,3,6,7-tetrametho...
关键词:free RADICAL reaction AZOBISISOBUTYRONITRILE tri-n-butyltin HYDRIDE (S)-(+)–tylophorine seco ANALOGUES 
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