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ADDICTION: 作品数：228被引量：201H指数：7; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：胡莹赵艳刘贤宇王秋海张娟更多>>; 相关机构：宁波大学宁波市第一医院睢宁县凌城中学河北昌黎第一中学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家科技支撑计划更多>>

DARG:An integrated knowledge base for analyzing addictive drug-related genes: 《Genes & Diseases》2025年第2期140-142,共3页Xu Wang Bei Yun Zihan Zhang Xiaoxi Wang Yifan Wu Yubo Hu Shiyi Fang Junjie Lv Lina Chen Wan Li; supported by the Natural Science Foundation of Heilongjiang Province,China (No.LH2021F043);the National Natural Science Foundation of China (No.61702141).; Drug addiction is a complex brain disease closely related to the expression and methylation of many genes.Differential genes can influence addiction,and some key differential genes may have a significant impact on the...; 关键词：DRUGS DIC ADDICTION

Noncanonical PI3Kγ signaling addiction is a therapeutic target in a subset of leukemias: 《The Innovation》2024年第6期21-22,共2页Yu Zhang Qian Kong Yonglong Zhang; supported by the National Natural Science Foundation of China(82472802 and 82073258);Natural Science Foundation of Shanghai(23ZR1448600).; Acute myeloid leukemia(AML)is a devastating disease with a median age of diagnosis of over 60 years.Thus,most AML patients are not eligible for intensive chemotherapy.Relapse remains common in patientswith AML despite...; 关键词：THERAPEUTIC diagnosis Acute

Management of Opioid Use Disorder in Sickle Cell Anaemia amidst Growing Menace in the General Population: 《Open Journal of Pediatrics》2023年第6期807-820,共14页Abimbola Aboluwarin Ayobola Ojuawo Oluwatobi Akanbi Lateef Quadri Hannah Elukpo Adebayo Oloko Kolade Ernest; Nigeria has a very high number of sickle cell disease (SCD) population with addition of 150,000 babies born annually with the disease. Early infant diagnosis and good care make many of these babies survive to adulthoo...; 关键词：Sickle Cell Disease Opioid Use Disorder Global Menace Treatment Centres True Addiction and Pseudo-Addiction

Glutamine addiction and therapeutic strategies in pancreatic cancer: 《World Journal of Gastrointestinal Oncology》2023年第11期1852-1863,共12页Lin-Lin Ren Tao Mao Pin Meng Li Zhang Hong-Yun Wei Zi-Bin Tian; Supported by the National Natural Science Foundation of China,No.81602056 and No.82273393;the Natural Science Foundation of Shandong Province,No.ZR2016HQ45 and No.ZR2020LZL004;the Shandong Traditional Chinese Medicine Science and Technology Project,No.2021M161.; Pancreatic cancer remains one of the most lethal diseases worldwide owing to its late diagnosis,early metastasis,and poor prognosis.Because current therapeutic options are limited,there is an urgent need to investigat...; 关键词：Pancreatic cancer Glutamine metabolism Cancer treatment Therapeutic strategies

Tumor-associated macrophage(TAM)-derived CCL22 induces FAK addiction in esophageal squamous cell carcinoma(ESCC)被引量：8: 《Cellular & Molecular Immunology》2022年第9期1054-1066,共13页Jie Chen Di Zhao Lingyuan Zhang Jing Zhang Yuanfan Xiao Qingnan Wu Yan Wang Qimin Zhan; This work was supported by the National Natural Science Foundation of China(81988101,81830086 and 81972243);the CAMS Innovation Fund for Medical Sciences(2019-I2M-5-081);Funding by the Major Program of Shenzhen Bay Laboratory(S201101004);the Guangdong Basic and Applied Basic Research Foundation(2019B030302012);the Fund of“San-ming”Project of Medicine in Shenzhen(No.SZSM201812088).; Tumor cell dependence on activated oncogenes is considered a therapeutic target,but protumorigenic microenvironment-mediated cellular addiction to specific oncogenic signaling molecules remains to be further defined.H...; 关键词：Tumor-associated macrophages Esophageal squamous cell carcinoma FAK Oncogene addiction

A multimodal integrative approach to model transcriptional addiction of thyroid cancer on RUNX2: 《Cancer Communications》2022年第9期892-896,共5页Emanuele Vitale Elisabetta Sauta Mila Gugnoni Federica Torricelli Veronica Manicardi Alessia Ciarrocchi; Fondazione Italiana per la Ricerca sul Cancro(project code:AIRC IG21772).; Dear Editor Aberrant gene expression sustains massive proliferation and stress adaptation under the regulation of oncogenic transcription factors(TFs)whose binding across the genome orchestrates in space and time tran...; 关键词：ADDICTION MODAL reservoir

Characterization of metabolic landscape in hepatocellular carcinoma被引量：2: 《World Journal of Gastrointestinal Oncology》2021年第9期1144-1156,共13页Jing Wu Ran Xue Rong-Tao Jiang Qing-Hua Meng; Supported by The Municipal Natural Science Foundation of Beijing,China,No.7192085;National Science and Technology Major Project of China,No.2018ZX10302206-003-007 and No.2017ZX10203202-001-005;The Capital Health Research and Development of Special,No.2018-1-3011;National Natural Science Foundation of China,No.81470877.; Hepatocellular carcinoma(HCC)is one of the most prevalent cancers worldwide,accounting for approximately 75%-85%of primary liver cancers.Metabolic alterations have been labeled as an emerging hallmark of tumors.Specia...; 关键词：Hepatocellular carcinoma Metabolic reprogramming GLYCOLYSIS Lipid metabolism Glutamine addiction Diagnosis and treatment

Methamphetamine induces cireTLk1 expression in cultured neurons and addiction mouse: 《解剖学杂志》2021年第S01期212-212,共1页Li Junwei Song Ruiheng Xi Kaiyan Hang Zhaofang Mu Shouhong Sun Jinhao; Circular RNA is a type of non-coding RNA which forms a loop structure.CircRNA was reported to exhibit cell-and tissue-specific patterns.Although accumulating evidences have showed circRNA plays an important role in ne...; 关键词：structure. expression. CORTEX

Targeting transcriptional regulators for treatment of anaplastic thyroid cancer: 《Journal of Cancer Metastasis and Treatment》2021年第1期381-398,共18页Woo Kyung Lee Sheue-Yann Cheng; supported by the Intramural Research Program of the Center for Cancer Research;National Cancer Institute,National Institutes of Health(ZIA BC 011191).; Dysregulation of genes perpetuates cancer progression.During carcinogenesis,cancer cells acquire dependency of aberrant transcriptional programs(known as“transcription addiction”)to meet the high demands for uncontr...; 关键词：Transcriptional addiction TRANSCRIPTION oncogene addiction cancer stem cell thyroid hormone receptors steroid receptor coactivators BET inhibitor anaplastic thyroid cancer

Childhood trauma,addiction&a modernized approach to treatment: 《Life Research》2020年第4期176-182,共7页Lisa Jo Symonds; This review serves to analyze the relationship between childhood trauma and addiction;provide an overview of the science behind addiction;analyze issues with current addiction treatment methods and protocols;as well a...; 关键词：ADDICTION TREATMENT RECOVERY DRUG POLICY Childhood trauma

ADDICTION