POLYCLONAL

作品数：26被引量：65H指数：3
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相关领域：医药卫生生物学更多>>
相关机构：首都医科大学更多>>
相关期刊：《Cellular & Molecular Immunology》《The Journal of China Universities of Posts and Telecommunications》《Journal of Bio-X Research》《Journal of Biomedical Science and Engineering》更多>>
相关基金：国家自然科学基金中国博士后科学基金广东省自然科学基金更多>>
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Single-cell exome sequencing reveals polyclonal seeding and TRPS1 mutations in colon cancer metastasis
《Signal Transduction and Targeted Therapy》2024年第10期4637-4652,共16页Jianqiang Cai Weilong Zhang Yalan Lu Wenjie Liu Haitao Zhou Mei Liu Xinyu Bi Jianmei Liu Jinghua Chen Yanjiang Yin Yiqiao Deng Zhiwen Luo Yi Yang Qichen Chen Xiao Chen Zheng Xu Yueyang Zhang Chaoling Wu Qizhao Long Chunyuan Huang Changjian Yan Yan Liu Lei Guo Weihua Li Pei Yuan Yucheng Jiao Wei Song Xiaobing Wang Zhen Huang Jianming Ying Hong Zhao 
National Key Research and Development Program of China(2023YFC3403800);National Natural Science Foundation of China(81972311,82303782);special Funds of the National Natural Science Foundation of China(82141127);CAMS Innovation Fund for Medical Sciences(CIFMS)(2021-12M-066);Non-profit Central Research Institution Fund of Chinese Academy of Medical Science(2019PT310026);Sanming Project of Medicine in Shenzhen(SZSM202011010).
Liver metastasis remains the primary cause of mortality in patients with colon cancer. Identifying specific driver gene mutations that contribute to metastasis may offer viable therapeutic targets. To explore clonal e...
关键词：METASTASIS COLON cancer 
Congophilic fibrils in the glomeruli with polyclonal immunoglobulin gamma staining-another cause for diagnostic overlap:A case report
《World Journal of Clinical Cases》2024年第17期3200-3205,共6页Maria Bernadette Che-Ying Chow Lucas Bushrow Irmeen Siddiqui April Chiu Mirza Hamirani Anjali A Satoskar 
BACKGROUND Glomerulopathy with fibrillary deposits is not uncommon in routine nephropathology practice,with amyloidosis and fibrillary glomerulonephritis being the two most frequently encountered entities.Renal amyloi...
关键词：Heavy and light chain amyloid Fibrillary glomerulonephritis DNAJB9 Serum immunofixation Protein electrophoresis Mass spectrometry Congo red Case report 
Genomic evolution during locoregional recurrence in colorectal cancer determined by whole-exome sequencing: a retrospective observational study被引量：1
《Journal of Bio-X Research》2022年第4期171-180,共10页Xiaoliang Lan Xiaoxiao Wu Chao Zhang Genxia Wei Bingbing Li Weihao Qiu Danyi Li Huanwen Wu Yanqing Ding Jie Yuan Zaixian Tai Zuoquan Yang Zhiyong Liang Dan Su Li Liang 
National Key R&D Program of China(No.2017YFC1309002);National Natural Science Foundation of China(Nos.81672821,81872041,81472313,81773101,81903002,and 82003059);China Postdoctoral Science Foundation(Nos.2019M652963 and 2020M682624);Key projects of Guangdong Natural Science Foundation(No.2018B0303110017);Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Cancer(No.2020B121201004).
Objective:The genomic landscapes of metastatic colorectal cancer(mCRC)have been extensively studied;however,the genetic mechanisms underlying the locoregional recurrence(LR)of CRC remain unclear.The objective of our s...
关键词：biomarker colorectal cancer locoregional recurrence polyclonal seeding tumor evolution 
How antithymocyte globulin,a polyclonal soup of the past century,when carefully dosed,has become crucial for hematopoietic stem cell transplantation with haplo-identical donors in the 21st century
《Science Bulletin》2021年第24期2445-2447,共3页Norbert Claude Gorin 
Hematopoeitic stem cell transplantation(HSCT)using a haploidentical family donor(HAPLO)was long thought to be non-feasible,essentially because of HLA incompatibility leading to graft rejection,severe acute(aGVH)and ch...
关键词：造血干细胞移植 acute doses 
IgY technology: Methods for developing and evaluating avian immunoglobulins for the in vitro detection of biomolecules被引量：2
《World Journal of Methodology》2021年第5期243-262,共20页Chrysoula-Evangelia Karachaliou Vyronia Vassilakopoulou Evangelia Livaniou 
The term“IgY technology”was introduced in the literature in the mid 1990s to describe a procedure involving immunization of avian species,mainly laying hens and consequent isolation of the polyclonal IgYs from the“...
关键词：Animal welfare Polyclonal IgYs Egg yolk IgY technology Relevant-to-IgYtechnology approaches In vitro immunodetection techniques 
Autophagy contributes to the feeding,reproduction,and mobility of Bursaphelenchus xylophilus at low temperatures被引量：2
《Acta Biochimica et Biophysica Sinica》2019年第8期864-872,共9页Hongbin Liu Xiaoqin Wu Yaqi Feng Lin Rui 
The pine wood nematode(PWN),Bursaphelenchus xylophilus,is the pathogen causing pine wilt disease(PWD),which is a devastating forest disease.At present,little is known about the defense mechanisms of the PWN,which limi...
关键词：PINE wood NEMATODE AUTOPHAGY autophagic activity anti-BxATG8 POLYCLONAL antibody temperature changes 
Resistant prolactinoma:Is it monoclonal or polyclonal?
《中国神经肿瘤杂志》2013年第4期241-241,共1页Kumar KV Prusty P 
Prolactinomas are solitary benign neoplasms and resistance to dopamine agonists occur in a small percentage of prolactinomas.Multiple pituitary adenomas are reported in less than 1%of pituitary adenomas and rarely res...
关键词：泌乳素 多克隆 单克隆 受体激动剂 垂体腺瘤 良性肿瘤 多巴胺 克隆表达 
Preparation of Polyclonal Antisera of Dairy Cow S100A12 Protein
《Agricultural Biotechnology》2013年第3期43-45,49,共4页Suizhong CAO Yafei CUI Xueping YAO Kang YONG Jishang LI Shumin YU 
Supported by China Postdoctoral Science Foundation(20090451250);Youth Fund of Sichuan Provincial Department of Education(09ZB054);Program for Changjiang Scholars and Innovative Research Team in University of the Ministry of Education(IRT0848)
[Objective] This study aimed to prepare dairy cow anti-S100A12 antisem and develop a highly effective and sensitive immunological detection reagent for further investigation of the functions of dairy cow S100A12. [Met...
关键词：Dairy cow S100A12 protein Polyclonal antisera 
Intravenous immunoglobulin suppresses IL-10 production by activated B cells in vitro
《Open Journal of Immunology》2012年第4期149-160,共12页Jun Tanaka Kumiko Hirano Yuzuru Sakamoto Akiko Sugahara-Tobinai Shota Endo Yumi Ito-Matsuoka Atsushi Nakano Masanori Inui Lars Nitschke Toshiyuki Takai 
A therapeutic preparation of polyclonal human IgG, i.e., intravenous immunoglobulin (IVIg), has been employed to treat several inflammatory and autoimmune disorders. B cells are supposed to be a target of IVIg, but th...
关键词：F(ab’)2 FRAGMENT Immune Inhibition ITIM RECEPTORS POLYCLONAL IgG SHP-1 
Cloning, Expression, and Immunogenicity Analysis of the CpsE Protein from Group B Streptococcus Isolated from Tilapia (Oreochromis Niloticus)
《Engineering（科研）》2012年第10期167-171,共5页Xi Fu Kaiyu Wang Jinlu Huang Jun Wang Hai Lian Yang He Lanmin Li Kaiyu Wang 
Group B Streptococcus (GBS) is a major cause of serious bacterial infection in numerous animal species. The production of capsular polysaccharide(CPs) is vital to GBS to evade host immunity. One of the genes that requ...
关键词：RECOMBINANT CpsE EXPRESSION Purification POLYCLONAL ANTIBODY 
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