ECONAZOLE

作品数：5被引量：13H指数：2
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相关领域：医药卫生更多>>
相关作者：刘芳邹萍吴耀辉肖娟张瑾更多>>
相关机构：中国农业大学四川大学华西医院华中科技大学同济医学院附属协和医院更多>>
相关期刊：《World Journal of Gastroenterology》《Chinese Chemical Letters》《Acta Pharmaceutica Sinica B》更多>>
相关基金：国家自然科学基金更多>>
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Repurposing econazole as a pharmacological autophagy inhibitor to treat pancreatic ductal adenocarcinoma被引量：2
《Acta Pharmaceutica Sinica B》2022年第7期3085-3102,共18页Ningna Weng Siyuan Qin Jiayang Liu Xing Huang Jingwen Jiang Li Zhou Zhe Zhang Na Xie Kui Wang Ping Jin Maochao Luo Liyuan Peng Edouard C.Nice Ajay Goel Suxia Han Canhua Huang Qing Zhu 
funded by Guangdong Basic and Applied Basic Research Foundation(2019B030302012,China);National Key R&D Program of China(2020YFA0509400 and 2020YFC2002705);NSFC(81821002,81790251 and 82130082,China);1.3.5 project for disciplines of excellence,West China Hospital,Sichuan University(ZYJC21042,China)。
Pancreatic ductal adenocarcinoma(PDAC)is characterized by the highest mortality among carcinomas.The pathogenesis of PDAC requires elevated autophagy,inhibition of which using hydroxychloroquine has shown promise.Howe...
关键词：ECONAZOLE AUTOPHAGY PDAC ATF3 AKT Organoid Trametinib Therapy 
Effects of Ca^(2+) channel blockers on store-operated Ca^(2+) channel currents of Kupffer cells after hepatic ischemia/reperfusion injury in rats被引量：10
《World Journal of Gastroenterology》2006年第29期4694-4698,共5页Nan Jiang Zong-Ming Zhang Liang Liu Chi Zhang Yan-Lu Zhang Zi-Chao Zhang 
the National Natural Science Foundation of China,No.30270532 Trans-Century Training Programme Foundation for the Talents by the Ministry of Education of China, No. 2002-48Shuguang Program Project of Shanghai Educational Committee,No.02SG20
AIM： To study the effects of hepatic ischemia/ reperfusion （I/R） injury on store-operated calcium channel （SOC） currents （Isoc） in freshly isolated rat Kupffer cells, and the effects of Ca^2＋ channel blockers,...
关键词：Kupffer cell ISCHEMIA/REPERFUSION Storeoperated calcium channel currents 2-aminoethoxydiphenylborate SK＆F96365 ECONAZOLE MICONAZOLE 
A preliminary study on the econazole induced endoplasmic reticulum related apoptosis in HL-60 leukemic cells
《The Chinese-German Journal of Clinical Oncology》2006年第5期376-378,共3页Zhenping Hu Wenli Liu Stuart Berger Yicheng Zhang 
Objective： To investigate the anti-leukemic function of econazole （Ec）, an azole anti-fungal drug. Methods： We compared efficacy of econazole to induce apoptosis in HL-60 cells with two other known endoplasmic ret...
关键词：LEUKEMIA endoplasmic reticulum stress APOPTOSIS 
Experimental Study on Apoptosis in Leukemia Cells Induced by Econazole
《The Chinese-German Journal of Clinical Oncology》2005年第2期102-104,共3页刘芳 邹萍 张敏 吴耀辉 肖娟 
This project was supported by a grant from the National Natural Sciences Foundation of China (No. 30370595).
To investigate apoptosis in mouse leukemia cell (WEHI-3) induced by Econazoleand its mechanism. Methods: Apoptosis induced by Econazole was examined by flow cytometry. Freecalcium ([Ca^(2+])i) was determined by Fura-2...
关键词：ECONAZOLE APOPTOSIS [Ca^(2+)]i CASPASE-12 
Separation of chiral drugs with sulfobutylether-β-cyclodextrin bycapillary zone electrophoresis被引量：1
《Chinese Chemical Letters》1999年第1期39-42,共4页Jun Ying LIU Yi Yang DONG Tian Song WANG Hu Wei LIU Al Jin HUANG yi Liang SUNI Zeng Pei SUN(Department of Chemistry． Peking University． Beijing 100871)(Natlonal Institute for the Control of Pharmaceutical and Biological Products，Beijing 100050) 
Sulfobutylether－β－cyclodextrin（SBE－β－CD）was used as a chiral selector tor separatingten chlral drugs with resolution 1．2 by capillary zone electrophoresls（CZE）， The backgroundelectrolylc solution compris...
关键词：Chiral separation sulfobutylether-β-cyclodextrin capillary zone electrophoresis anlsodamlne bencynonate ECONAZOLE ESMOLOL glycopynonate lobeline METHOXAMINE PHENYLEPHRINE plnacidll TERAZOSIN 
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