METABOLOMIC

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相关作者：张哲毕惠嫦杨宇卓赵一懿傅欣彤更多>>
相关机构：中山大学北京大学第三医院北京市药品检验所华中农业大学更多>>
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Metabolomic profiling and prognostication in CoVID-19 acute respiratory distress syndrome
《Journal of Intensive Medicine》2025年第1期108-110,共3页David Furfaro Xiaoyu Che Wenhao Gou Matthew J.Cummings Nischay Mishra Daniel Brodie Thomas Briese Oliver Fiehn W.Ian Lipkin Max R.O'Donnell 
CHEST Foundation Grant in COVID-192020(DMF).
To the Editor,Coronavirus disease 2019(COVID-19)-related acute respiratory distress syndrome(ARDS)is biologically and clinically heterogeneous with a broad spectrum of organ dysfunction and illness severity.[1] In COV...
关键词：DISTRESS ACUTE Metab 
Effects of aflatoxin B1 on subacute exposure of hybrid groupers(Epinephelus fuscoguttatus♀×Epinephelus lanceolatus♂):Growth,liver histology,and integrated liver transcriptome and metabolome analysis
《Animal Nutrition》2024年第4期192-214,共23页Hao Liu Shuqing Liang Weibin Huang Yuanzhi Yang Menglong Zhou Baiquan Lu Biao Li Wenshan Cai Hengyang Song Beiping Tan Xiaohui Dong 
supported financially by the Research and Demonstration of Precision Functional Compound Feed Technology of Major Cultured Fishes and Shrimps in South China,China(2021B0202050002);the Department of Education of Guangdong Province,China(2021ZDZX4005);the China Agriculture Research System of MOF and MARA,China(CARS-47).
With the increasing incorporation of plant-based ingredients into the grouper diet,the issue of aflatoxin B1 (AFB1) contamination in the diet has become a significant concern.In this study,the negative effects of AFB1...
关键词：Aflatoxin B1 Hybrid grouper Transcriptomic METABOLOMIC LIVER 
Effect of exogenous free N^(ε)-(carboxymethyl)lysine on diabetes-associated cognitive dysfunction:neuroinflammation,and metabolic disorders
《Food Science and Human Wellness》2024年第5期2970-2981,共12页Huang Zhang Lan Mo Xi Chen Mei Li Maiquan Li Yang Xu Maomao Zeng Zhiyong He Qingwu Shen Jie Chen Wei Quan 
supported by the National Natural Science Foundation of China(32302258,32172317);Changsha Municipal Natural Science Foundation(kq2202223).
Diabetes-associated cognitive dysfunction has already been attracted considerable attention.Advanced glycation end products(AGEs)from daily diets are thought to be a vital contributor to the development of this diseas...
关键词：Diabetes Cognitive dysfunction N^(ε)-(carboxymethyl)lysine NEUROINFLAMMATION METABOLOMIC 
Integrated 16S rRNA sequencing and metabolomic analysis reveals the potential protective mechanism of Germacrone on diabetic nephropathy in mice
《Acta Biochimica et Biophysica Sinica》2024年第3期414-426,共13页Yunguang Wang Xinxin He Mengjiao Xue Huan Yu Qiang He Juan Jin 
This work was supported by the grants from the Zhejiang Provincial Traditional Chinese Medicine Science and Technology Project(No.2022ZB273);the Huadong Medicine Joint Funds of the Zhejiang Provincial Natural Science Foundation of China(No.LHDMY24H270002);the Zhejiang Provincial Medical and Health Technology Project(No.2023KY158);the Cultivation Program for Excellent Young Talents of Hangzhou First People’s Hospital(No.YQNYC202131);the Science and Technology Special Project of Hangzhou Biomedicine and Health Industry Development Support(No.2021WJCY253).
Diabetic nephropathy(DN)is a severe complication of diabetes and the leading cause of end-stage renal disease and death.Germacrone(Ger)possesses anti-inflammatory,antioxidant and anti-DN properties.However,it is uncle...
关键词：diabetic nephropathy GERMACRONE gut microbiota untargeted fecal metabolomics 16S rRNA sequencing 
Washed microbiota transplantation for Crohn’s disease:A metagenomic,metatranscriptomic,and metabolomic-based study
《World Journal of Gastroenterology》2024年第11期1572-1587,共16页Shi-Ju Chen Da-Ya Zhang Xia Wu Fa-Ming Zhang Bo-Ta Cui Yi-Hao Huang Zu-Lun Zhang Rui Wang Fei-Hu Bai 
Supported by the Innovation Platform for Academicians of Hainan Province,No.YSPTZX202313;Hainan Province Clinical Medical Center,No.2021818;Hainan Provincial Health Industry Research Project,No.22A200078;Hainan Provincial Postgraduate Innovation Research Project,No.Qhyb2022-133;Hainan Medical University Graduate Student Innovative Research Project,No.HYYB2022A18;Nanjing Medical University Fan Daiming Research Funds for Holistic Integrative Medicine,No.2020-3HIM.
BACKGROUND Fecal microbiota transplantation(FMT)is a promising therapeutic approach for treating Crohn’s disease(CD).The new method of FMT,based on the automatic washing process,was named as washed microbiota transpl...
关键词：Crohn’s disease Clinical trials Fecal microbiota transplant METAGENOME Metatranscriptome METABOLOME 
Incremental Metabolic Benefits from Cryoablation for Paroxysmal Atrial Fibrillation: Insights from Metabolomic Profiling
《Cardiovascular Innovations and Applications》2024年第1期1-14,共14页Mengjie Xie Fuding Guo Jun Wang Yijun Wang Zhihao Liu Jing Xie Zhuo Wang Songyun Wang Liping Zhou Yueyi Wang Hong Jiang Lilei Yu 
supported by grants from National Natural Science Foundation of China(82241057,82270532,81970287,82100530,and 82200556);the Foundation for Innovative Research Groups of Natural Science Foundation of Hubei Province,China(2021CFA010).
Background:Cryoablation(CRYO)is a novel catheter ablation technique for atrial fibrillation(AF).However,un-certainty persists regarding the role of metabolic modifications associated with CRYO.This study was aimed at ...
关键词：CRYOABLATION metabolomics atrial fibrillation polyunsaturated fatty acids neuroactive ligand-receptor interaction pathways 
Intestinal microbiota dysbiosis and liver metabolomic changes during brain death
《Journal of Intensive Medicine》2023年第4期345-351,共7页Ruolin Tao Wenzhi Guo Tao Li Yong Wang Panliang Wang 
supported by the National Natural Science Foundation of China (grant numbers:81,900,596,81,671,958).
Background Whether a causative link exists between brain death(BD)and intestinal microbiota dysbiosis is unclear,and the distortion in liver metabolism associated with BD requires further exploration.Methods A rat mod...
关键词：Brain death Liver graft MICROBIOTA Metabonomic 
Characterization of gut microbial and metabolite alterations in faeces of Goto Kakizaki rats using metagenomic and untargeted metabolomic approach
《World Journal of Diabetes》2023年第3期255-270,共16页Jin-Dong Zhao Min Sun Yan Li Chan-Juan Yu Ruo-Dong Cheng Si-Hai Wang Xue Du Zhao-Hui Fang 
Supported by the University Scientific Research Projects of Anhui,No. KJ2020A0401 and 2022AH050491;the open fund of the Ministry of Education Key Laboratory of Glucolipid Metabolic Disorder,No. GYDKFXM01;the Anhui University Collaborative Innovation Project,No. GXXT-2020-025;the National Natural Science Foundation of China,No. 82174153;the National Key Research and Development Program,No. 2018YFC1704202;the Anhui Provincial Quality Engineering Project of Universities,No. 2021jyxm0834;the Major and Difficult Diseases Project of Anhui Province,No. 2021zdynjb06;the Clinical Research Project of Anhui University of Traditional Chinese Medicine,No. 2021yfylc01
BACKGROUND In recent years,the incidence of type 2 diabetes(T2DM)has shown a rapid growth trend.Goto Kakizaki(GK)rats are a valuable model for the study of T2DM and share common glucose metabolism features with human ...
关键词：Type 2 diabetes mellitus Gut microbial Metabolites Goto-Kakizaki rats METAGENOMICS Untargeted metabolomics 
Metabolomic Profiling of Mice Exposed toα-amanitin Using Ultra-performance Liquid Chromatography Quadrupole Time-of-flight Tandem Mass Spectrometry
《Biomedical and Environmental Sciences》2023年第3期289-294,共6页LI Lei ZHENG Chong YE Jian Fang ZHU Kai ZHOU Yi Bing LIU Jia GAO Ming WU Yu Tian LIU Yong Ting LIU Li Ya LIN Ye LI Hai Chang ZHANG Quan GUO Hua 
financially supported by Guizhou Provincial Science and Technology Support Program[No.Qiankehe[2021]496];Science and Technology Fund of Guizhou Health Commission[No.gzwkj2021-407];National Major Research Project[No.2017YFC1601805];Guizhou Provincial Science and Technology Support Program[No.Qiankehe[2017]2972]。
Numerous instances of poisoning caused by the ingestion of mushrooms are reported annually worldwide,with most mushroom poisoning deaths caused by the ingestion of toxic amanita fungi.Amatoxin is the main toxic compon...
关键词：Metab ani annually 
Can metabolomic signature foster precision medicine approaches in nonalcoholic fatty liver disease arena?
《Hepatobiliary Surgery and Nutrition》2022年第6期886-888,共3页Amedeo Lonardo 
Abnormal chemical reactions disrupting physiological bio-transformations in human body set the stage for the development of metabolic disorders(1).Clinically and epidemiologically,the metabolic syndrome is the most de...
关键词：SIGNATURE globally FOSTER 
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