GATEKEEPER

作品数：41被引量：41H指数：4
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相关领域：自动化与计算机技术电子电信更多>>
相关作者：杨桂荣刘波维孟凡淇周绪川袁志毅更多>>
相关机构：电子科技大学暨南大学四川省社会科学院盐城师范学院更多>>
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foxl2l is a germ cell-intrinsic gatekeeper of oogenesis in zebrafish
《Zoological Research》2024年第5期1116-1130,共15页Zhiqin Ren Ding Ye Naike Su Chaofan Wang Lijia He Houpeng Wang Mudan He Yonghua Sun 
supported by the National Natural Science Foundation of China(32025037);Ministry of Science and Technology of China(2023YFD2401603);Ministry of Agriculture and Rural Affairs of China(NK2022010207);Science and Technology Special Fund of Hainan Province(ZDYF2024XDNY256);Natural Science Foundation of Wuhan。
Zebrafish serve as a valuable model organism for studying germ cell biology and reproductive processes.The AB strain of zebrafish is proposed to exhibit a polygenic sex determination system,where most males initially ...
关键词：foxl2l DMRT1 OOGENESIS Sex determination MEIOSIS 
Defining the growth paths of strategic scientists based on case studies
《Cultures of Science》2024年第3期198-209,共12页Wuyunqiqige Jiangyang Yuan 
supported by a research project titled ‘The Growth Path of Strategic Scientists based on case studies’ launched by the National Academy of Innovation Strategy,CAST (grant no 2022-sjzx-05)
In this paper, 18 scientists from China and other countries were selected for consideration as case studies of‘strategic scientists'. They were chosen according to their involvement in science and technology policy d...
关键词：Strategic scientists case study growth path GATEKEEPER cultivation and use of strategic scientists 
数据高真实性的车联网Gatekeeper+协议研究及验证
《计算机应用与软件》2024年第7期115-120,共6页陈肜心 陈世超 刘杰 杨佳 
湖南省教育厅科学研究项目(22C0223)。
车联网通信中数据包的真实性直接关系到车联网通信的安全性。新型车载广播认证协议Gatekeeper具有源身份认证和防护DoS攻击的优势,将是未来主流的车联网通信协议之一。但目前其缺乏对数据真实性的保障机制,导致车载通信会因数据真实性...
关键词：车联网 Gatekeeper+协议 数据真实性 模型检测技术 
mTORC2 acts as a gatekeeper for mTORC1 deficiency-mediated impairments in ILC3 development被引量：1
《Acta Pharmacologica Sinica》2023年第11期2243-2252,共10页Ya-fei Deng Shu-ting Wu Hong-yan Peng Lei Tian Ya-na Li Yao Yang Meng Meng Lan-lan Huang Pei-wen Xiong Song-yang Li Qing-lan Yang Li-li Wang Xiao-yao Li Li-ping Li Xiu-lan Lu Xiao-hui Li Yan-ling Wei Zheng-hui Xiao Jian-hua Yu You-cai Deng 
funding from the National Natural Science Foundation of China(Nos.81874313 and 81922068 to YCD;No.81703521 to YFD,No.81900055 to HYP,and No.82070571 to YLW);This study was also supported by funding from the Natural Science Foundation of Hunan Province(No.2023JJ30320 to YFD and No.2021JJ40274 to HYP);the Natural Science Foundation of Changsha,Hunan Province(No.kq2208090 to YFD);the Project of Army Medical University(2109XQ04 to YCD).
Group 3 innate lymphoid cells(ILC3s)are mediators of intestinal immunity and barrier function.Recent studies have investigated the role of the mammalian target of rapamycin complex(mTOR)in ILC3s,whereas the mTORC1-rel...
关键词：Group 3 innate lymphoid cells mTORC1 mTORC2 NFIL3 single-cell RNA sequencing 
Development of the Life Gatekeeper suicide prevention training programme in China:a Delphi study被引量：3
《General Psychiatry》2023年第5期383-392,共10页Chengxi Cai Chen Yin Yongsheng Tong Diyang Qu Yunzhi Ding Daixi Ren Peiyu Chen Yi Yin Jing An Runsen Chen 
funding from Research Fund of VankeSchool of Public Health(100009001);funding from Shuimu Tsinghua Scholar;funding from Beijing High Level Public HealthTechnical Specialist Development Fund(Discipline backbone-02-07).
Background Youth suicide has been a pressing public mental health concern in China,yet there is a lack of gatekeeper intervention programmes developed locally to prevent suicide among Chinese adolescents.Aims The curr...
关键词：DELPHI PREVENTION PROGRAMME 
Single-nucleus transcriptomics reveals a gatekeeper role for FoxP1 in primate cardiac aging被引量：4
《Protein & Cell》2023年第4期279-293,共15页Yiyuan Zhang Yandong Zheng Si Wang Yanling Fan Yanxia Ye Yaobin Jing Zunpeng Liu Shanshan Yang Muzhao Xiong Kuan Yang Jinghao Hu Shanshan Che Qun Chu Moshi Song Guang-Hui Liu Weiqi Zhang Shuai Ma Jing Qu 
supported by the National Key Research and Development Program of China(2018YFC2000100);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA16000000);the National Natural Science Foundation of China(81921006,92149301,92168201,82125011,91949209,92049304,92049116,32121001,82192863,82122024,82071588,81901432,32000510,81861168034,32000500,81901433,81870228,81922027);the National Key Research and Development Program of China(2020YFA0804000,2020YFA0113400,2018YFA0107203,2020YFA0112200,2021YFF1201005,2021ZD0202401);the Program of the Beijing Natural Science Foundation(Z190019,JQ20031);K.C.Wong Education Foundation(GJTD-2019-06,GJTD-2019-08),Young Elite Scientists Sponsorship Program by CAST(YESS20200012,YESS20210002);The Pilot Project for Public Welfare Development and Reform of Beijing-affliated Medical Research Institutes(11000022T000000461062);CAS Project for Young Scientists in Basic Research(YSBR-012),Youth Innovation Promotion Association of CAS(E1CAZW0401,2022083);the Informatization Plan of Chinese Academy of Sciences(CAS-WX2021SF-0301,CASWX2022SDC-XK14),the Tencent Foundation(2021-1045).
Aging poses a major risk factor for cardiovascular diseases,the leading cause of death in the aged population.However,the cell type-specific changes underlying cardiac aging are far from being clear.Here,we performed ...
关键词：single-nucleus RNA-sequencing PRIMATE AGING FOxP1 CARDIOMYOCYTE 
Mesoporous polydopamine delivery system for intelligent drug release and photothermal-enhanced chemodynamic therapy using MnO_(2) as gatekeeper被引量：1
《Regenerative Biomaterials》2023年第1期1566-1576,共11页Zhaoyang Wang Zekai Li Yuehua Shi Leyong Zeng 
supported by the National Natural Science Foundation of China(U20A20254,U1732127 and 51772074);Natural Science Foundation of Hebei Province(C2020201025);Central Government Guided Local Science and Technology Development Project of Hebei Province(226Z1302G);Natural Science Interdisciplinary Research Program of Hebei University(DXK202002);Research Innovation Team of College of Chemistry and Environmental Science of Hebei University(hxkytd-py2103).
The non-specific leakage of drugs from nanocarriers seriously weakened the safety and efficacy of chemotherapy,and it was very critical of constructing tumor microenvironment(TME)-responsive delivery nanocarriers,achi...
关键词：mesoporous polydopamine MnO_(2)gatekeeper chemotherapy photothermal therapy chemodynamic therapy 
Mediator complex subunit 12 is a gatekeeper of SARS-CoV-2 infection in breast cancer cells
《Genes & Diseases》2022年第1期5-8,共4页Shengjie Zhang Fabao Liu Peter Halfmann Ryan TBehrens Peng Liu Sean JMcilwain Irene MOng Kristine Donahue Yidan Wang Yoshihiro Kawaoka Nathan Sherer Wei Xua 
This project was supported by grants from the National Institutes of Health(No.R01 CA236356 and R01 CA213293)to Wei Xu;University of Wisconsin Carbone Cancer Center Support Grant(No.P30 CA014520);Dr.Shengjie Zhang received partial salary support from the National Natural Science Foundation of China(No.81502603).
Cancer patients are at increased risk for severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection and mortality.Like other viruses in the SARS family,SARS-CoV-2 employs two host proteins,angiotensin-conve...
关键词：INFECTION ACE2 cancer 
Liver sinusoidal endothelial cells-The liver’s gatekeeper
《Journal of Hainan Medical University》2022年第4期67-72,共6页Zi-Bing Qian Qi Zhang Pei-Yun Zeng Zhi-Xiu Zhang Jing Liu 
National Natural Science Foundation of China(No.81760151)。
Hepatic sinusoidal endothelial cell(LSECs),as the sinusoidal capillary channel of the liver,is the most abundant non-parenchymal cell group in the liver. LSECs not only forms a barrier in the hepatic sinusoid,but also...
关键词：Hepatic sinusoidal endothelial cells Immunity Chronic liver disease Inflammation SENESCENCE 
Comparison of Gatekeeping and Non-gatekeeping Designs in a Service System with Delay-sensitive Customers被引量：1
《Journal of Systems Science and Systems Engineering》2021年第2期125-150,共26页Wenhul Zhou Xiuzhang Li Qu Qian 
This paper is motivated by a concern in China's current medical practice in which patients can bypass the primary care and seek secondary care directly.We employ a queueing approach to examine two settings,i.e.the gat...
关键词：Customer delay sensitivity GATEKEEPER service capacity cure fraction total social cost 
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