DEGUELIN

作品数：8被引量：19H指数：2
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相关领域：医药卫生更多>>
相关作者：朱一平杨艳莉更多>>
相关机构：复旦大学南京医科大学更多>>
相关期刊：《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》《Advances in Bioscience and Biotechnology》《International Journal of Agricultural and Biological Engineering》更多>>
相关基金：国家自然科学基金更多>>
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The Akt Pathway Inhibitor Degeulin Prevents Staphylococcal Enterotoxin B Induced Splenocyte Proliferation and Inflammation
《Advances in Bioscience and Biotechnology》2017年第1期1-12,共12页Sarah Joanne Christine Whitfield Jane Elizabeth Risdall Gareth Griffiths Ethel Diane Williamson Alun James Carter 
Staphylococcal Enterotoxin B (SEB) is considered a potential biological weapon. It is toxic by both inhalation and ingestion. Effects of ingestion include fever, vomiting and diarrhoea, while inhalation may additional...
关键词：STAPHYLOCOCCAL ENTEROTOXIN B DEGUELIN Therapy INFLAMMATION Biological WEAPON 
Modulation of signal transduction pathways by natural compounds in cancer被引量：2
《Chinese Journal of Natural Medicines》2015年第10期730-742,共13页Alok Ranjan Neel M.Fofaria Sung-Hoon Kim Sanjay K.Srivastava 
supported in part by NIH/National Cancer Institute R01 grant CA129038(to S.K.S);MEST grant 2012–0005755(to S.H.K)
Cancer is generally regarded as the result of abnormal growth of cells. According to World Health Organization, cancer is the leading cause of mortality worldwide. Mother nature provides a large source of bioactive co...
关键词：Natural compounds CAPSAICIN Curcumin Diindolylmethane(DIM) ISOTHIOCYANATE PIPERINE DEGUELIN Cucurbitacin B CANCER 
Regulatory Effects of Deguelin on Proliferation and Cell Cycle of Raji Cells被引量：1
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2013年第4期491-495,共5页熊金蓉 刘红利 
supported by grants from the National Natural Science Foundation of China(No.30900597);the Science Foundation of Hubei Health Department(No.JX6B08)
Summary： The underlying mechanism of deguelin regulating the cell cycle in human Burkitt＇s lym phoma cell line Raji cells in vitro, and the cytotoxicity of deguelin to Raji cells and human peripheral blood monocular...
关键词：DEGUELIN cell cycle apoptosis Burkitt＇s lymphoma 
Extraction and purification of deguelin from Derris trifoliata Lour root
《International Journal of Agricultural and Biological Engineering》2009年第4期98-103,共6页Jian Wenjie Fang Yuchun Gan Chunji Wu Yunhui Pang Jie 
This article deals with extraction and purification of deguelin,which is a main rotenoid occurred in the root of Derris trifoliate Lour.Deguelin has gained much attention of scientists because of its potential ability...
关键词：DEGUELIN EXTRACTION PURIFICATION silica gel column chromatography 
Anti-cancer Effects of Deguelin on Human Leukemia K562 and K562/ADM Cells In Vitro
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2007年第2期149-152,共4页吴秋玲 陈燕 刘红利 何静 
This project was supported by a grant from the National Natural Sciences Foundation of China (No. 30472267)
In order to investigate the anti-cancer effects of deguelin and on K562 and K562/ADM cells in vitro and the underlying molecular mechanism and compare the cytotoxicity of deguelin on K562, K562/ADM cells and human per...
关键词：DEGUELIN K562 cell K562/ADM cell apoptosis cell cycle 
Deguelin inhibits expression of IκBα protein in Raji and U937 cells被引量：1
《Acta Pharmacologica Sinica》2006年第4期485-490,共6页Wei-hua CHEN Yan CHEN Guo-hui CUI 
Project supported by the National Natural Science Foundation of China(№30472267).
Aim： To determine whether deguelin can regulate the expression of nuclear factor kappa B （NF-κB） binding protein （IκBα） in U937 human leukemia cells and Raji human B lymphoma cells. Methods： The localization ...
关键词：DEGUELIN IΚBΑ nuclear factor kappa B tumor necrosis factor-α APOPTOSIS Raji cells U937 cells 
Deguelin regulates nuclear pore complex proteins Nup98 and Nup88 in U937 cells in vitro^1被引量：7
《Acta Pharmacologica Sinica》2005年第10期1265-1273,共9页Hong-li LIU Yan CHEN Guo-hui CUI Qiu-ling WU Jing HE Wei-hua CHEN Jian-feng ZHOU 
Project supported by the National Natural Science Foundation of China (№ 30472267)
Aim： To investigate the anticancer effects and the molecular mechanisms of deguelin on human U937 leukemia cells, and to explore the underlying mechanism regulating nucleoporin 98 （Nup98） and nucleoporin 88 （Nup88...
关键词：DEGUELIN U937 cells NUCLEOPORIN Nup98 NUP88 
Regulating expressions of cyclin D1,pRb,and anti-cancer effects of deguelin on human Burkitt's lymphoma Daudi cells in vitro被引量：10
《Acta Pharmacologica Sinica》2005年第7期873-880,共8页Hong-liLIU YanCHEN Guo-huiCUI Qiu-lingWU JingHE 
the National Natural Science Foundation of China(No 30472267).
Aim:To investigate anticancer effects and molecular mechanism of deguelin on human Burkitt's lymphoma Daudi cells in vitro and compare the cytotoxicities of deguelin on Daudi cells and human peripheral blood monocular...
关键词：DEGUELIN Daudi cells cyclin D1 PRB apoptosis 
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