KAINATE

作品数：6被引量：12H指数：2
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相关作者：张玉茜于榕许奇徐昕红赵娟更多>>
相关机构：安徽医科大学长沙医学院复旦大学上海医学院上海交通大学更多>>
相关期刊：《Neural Regeneration Research》《Chinese Medical Sciences Journal》《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》《Acta Pharmacologica Sinica》更多>>
相关基金：国家自然科学基金北京市自然科学基金霍英东教育基金更多>>
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Connexin 36 Mediates Orofacial Pain Hypersensitivity Through GluK2 and TRPA1被引量：1
《Neuroscience Bulletin》2020年第12期1484-1499,共16页Qian Li Tian-Le Ma You-Qi Qiu Wen-Qiang Cui Teng Chen Wen-Wen Zhang Jing Wang Qi-Liang Mao-Ying Wen-Li Mi Yan-Qing Wang Yu-Xia Chu 
the National Natural Science Foundation of China(81971056,31600852,81771202,and 81873101);the Innovative Research Team of Highlevel Local Universities in Shanghai;the Foundation of Science,Technology and Innovation Commission of Shenzhen Municipality(JCYJ20180302153701406);the National Key R&D Program of China(2017YFB0403803);the Shanghai Municipal Science and Technology Major Project(2018SHZDZX01);ZJLab。
Trigeminal neuralgia is a debilitating condition,and the pain easily spreads to other parts of the face.Here,we established a mouse model of partial transection of the infraorbital nerve(pT-ION)and found that the Conn...
关键词：Orofacial pain Gap junction Glutamate receptor ionotropic kainate 2 Transient receptor potential A1 
Overexpression of C-terminal fragment of glutamate receptor 6 prevents neuronal injury in kainate-induced seizure via disassembly of Glu R6-PSD95-MLK3 signaling module被引量：7
《Neural Regeneration Research》2014年第23期2059-2065,共7页Jie Mou Xiaomei Liu Dongsheng Pei 
supported by the National Natural Science Foundation of China,No.30800309,81372172;the Educational Science Foundation of Jiangsu Province,China,No.10KJB350005;the Xuzhou Science Foundation in China,No.XZZD1153;the President Special Grant of Xuzhou Medical College in China,No.09KJZ20;a grant from the Zhenxing Project Foundation of XZMC
Our previous study showed that when glutamate receptor （GluR）6 C terminus-containing peptide conjugated with the human immunodeficiency virus Tat protein （GluR6）-9c is delivered into hippocampal neurons in a brain...
关键词：nerve regeneration brain injury hippocampal neuronal injury seizures ADENOVIRUS GLUR6 PSD95 MLK3 KAINATE apoptosis JNK NSFC grants neural regeneration 
Neuroprotective effects of flavonoids extracted from licorice on kainate-induced seizure in mice through their antioxidant properties被引量：4
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2013年第11期1004-1012,共9页Ling-hui ZENG Hua-dan ZHANG Cai-ju XU Yu-jia BIAN Xue-jiao XU Qiang-min XIE Rong-hua ZHANG 
Project supported by the Scientific Research Foundation for Returned Scholars of the Ministry of Education of China(2011);the Project of Experiment Animal Platform of Department of Science and Technology of Zhejiang Province(No.2013C37026);the Hangzhou Science and Technology Development Plan(No.20100333T24),China
A relationship between status epilepticus(SE)and oxidative stress has recently begun to be recognized.To explore whether the flavonoids extracted from licorice(LFs)have any protective effect on kainate(KA)-induced sei...
关键词：SEIZURE KAINATE Flavonoid LICORICE Antioxidant Malondialdehyde(MDA) Superoxide dismutase(SOD 
Spatio-temporal Expression Study of Phosphorylated 70-kDa Ribosomal S6 Kinase (p70S6k) in Mesial Temporal Lobe Epilepsy
《Chinese Medical Sciences Journal》2012年第1期7-10,共4页Xiao-liang Xing Long-ze Sha Yuan Yao Yan Shen Li-wen Wu Qi Xu 
Supported by National Natural Science Foundation of China (31021091, 30971001);Beijing Natural Science Foundation (7102109);Fok Ying Tong Education Foundation (121024)
Objective To determine the spatio-temporal expression of p70S6k activation in hippocampus in mesial temporal lobe epilepsy. Methods Temporal lobe epilepsy model was established by stereotaxically unilateral and intrah...
关键词：mesial temporal lobe epilepsy P70S6K kainate acid IMMUNOREACTIVITY 
Temperature- and concentration-dependence of kainate-induced y oscillation in rat hippocampal slices under submerged condition
《Acta Pharmacologica Sinica》2012年第2期214-220,共7页Cheng-biao LU Zhi-hua WANG Yan-hong ZHOU Martin VREUGDENHIL 
Aim： Fast neuronal network oscillation at the y frequency band （y oscillation： 30-80 Hz） has been studied extensively in hippocampal slices under interface recording condition. The aim of this study is to establis...
关键词：y oscillation neuronal network hippocampus kainite submerged slice 
Allopregnanolone与GABA在大鼠大脑的皮层细胞中对kainate诱导乳酸脱氢酶释放的不同作用
《Acta Pharmacologica Sinica》2002年第8期680-684,共5页于榕 徐昕红 等 
目的：观察Allopregnanolone与γ氨基丁酸（BABA）对兴奋性毒性的作用。方法：对原代培养大鼠大脑的皮层细胞，采用kainate(KA)处理，诱导发兴奋性毒性，通过测定释放至细胞培养基中的乳酸盐脱氢酶（LDH）活性，观察Allopregnanolone与G...
关键词：别孕烷醇酮 神经固醇 兴奋性毒性 大鼠 大脑 皮层细胞 乳酸脱氢酶释放 作用 GABAA受体 
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