云南高校图书馆联盟文献共享服务平台- NIMESULIDE

NIMESULIDE: 作品数：36被引量：145H指数：5; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：郭贵龙张筱骅周素梅尤捷金纯更多>>; 相关机构：温州医学院附属第一医院华中科技大学南昌大学第二附属医院内蒙古医科大学更多>>; 相关期刊：《药学学报》《Chemical Research in Chinese Universities》《内蒙古医学杂志》《肿瘤防治研究》更多>>; 相关基金：国家自然科学基金广西壮族自治区自然科学基金江西省教育厅科学技术研究项目更多>>

Nimesulide increases the aldehyde oxidase activity of humans and rats: 《Acta Pharmacologica Sinica》2020年第6期843-851,共9页Lei Zhou Xiao-yan Pang Xiang-yu Hou Lu Liu Zi-tao Guo Xiao-yan Chen; This work was supported by the National Natural Science Foundation of China(Grants 81573500 and 81573351);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA 12050306).; An increasing number of drugs are metabolized by aldehyde oxidase(AOX),but AOX-mediated drug interactions are seldom reported due to the lack of appropriate inhibitors and inducers.A recent study reported that nimesul...; 关键词：NIMESULIDE aldehyde oxidase induction METHOTREXATE HEPATOCYTES PHARMACOKINETICS drug interaction

Clinical observation on treatment of cancer pain with TCM oriented drugs combined with oxycodone sustained-release tablets and nimesulide sustained-release tablets: 《TMR Cancer》2018年第4期118-123,共6页Feng-Jiao He Ke-Xiong Li Pu-Hua Zeng Hai-Yan Yi Xiao-Lan Jian; Objective： To study the effect of the transdermal preparation of traditional Chinese medicine in treating cancer pain. Methods： From October 2016 to January 2018, 126 patients with cancer pain were enrolled and divi...; 关键词：Chinese medicine directed drug Oxycodone sustained-release tablets Cancer pain Clinical efficacy

Optimization and characterization of nimesulide bilayer tablets by response surface methodology被引量：1: 《Journal of Chinese Pharmaceutical Sciences》2014年第2期89-93,共5页单利范云周王玉丽陈红鸽高春生杨美燕; Important National Science & Technology Specific Projects of China(Grant No.2012ZX09301003-001-009); The objectives of this present investigation were to develop and formulate nimesulide bilayer tablets by using different polymer combinations and fillers, to optimize the formulations for different drug release variab...; 关键词：NIMESULIDE Bilayer tablets Orthogonal design Central composite design-response surface methodology Sustainedrelease Fast release

Nimesulide对低氧条件下人肝癌细胞HepG2的增殖抑制作用及机制: 《广东医学》2013年第3期356-359,共4页吴梨华廖新根熊强胡国柱; 江西省教育厅科学技术研究项目(编号:GJJ08073); 目的探讨环氧合酶抑制剂Nimesulide对低氧条件下人肝癌细胞HepG2增殖的影响及分子机制。方法将人肝癌细胞HepG2分为6组,分别作如下处理:常氧(21%O2)不加药、常氧+50μmol/L Nimesulide、缺氧(1%O2)不加药、缺氧+50μmol/L Nimesulide、...; 关键词：环氧合酶抑制剂细胞低氧缺氧诱导因子-1α 肝癌细胞增殖

Nimesulide抗肺癌作用的体内及体外研究: 《内蒙古医学院学报》2011年第6期477-482,共6页于琳张卿; 国家自然科学基金（30560175）; 目的：探讨选择性CoX-2抑制剂Nimesulide对肺腺癌体内、体外的影响及其机制。方法：（1）采用MrITr比色法观察Nimesulide对肺腺癌A549细胞生长的影响，免疫细胞化学法测定肺癌A549细胞中PCNA、bcl-2基因蛋白表达水平；（2）建立肺腺癌...; 关键词：NIMESULIDE 肺腺癌蛋白表达

Determination of Camylofin Dihydrochloride and Nimesulide in Pharmaceutical Preparation by Gas Chromatography: 《American Journal of Analytical Chemistry》2011年第8期944-952,共9页Rajeev Kumar R. Singh Manapragada V. Rathnam Sangeeta J. Singh Raju V. K. Vegesna; This research paper describes simple analytical method for determination of Camylofin dihydrochloride and Nimesulide in tablet formulation by Gas chromatography method. Benzoic acid was used as internal standard. Vali...; 关键词：CAPILLARY COLUMN Gas CHROMATOGRAPHY PHARMACEUTICAL Preparations Camylofin Dihydrochloride NIMESULIDE

Fe_3O_4 Magnetic Nanoparticles Modified Electrode as a Sensor for Determination of Nimesulide被引量：1: 《Chemical Research in Chinese Universities》2011年第4期566-569,共4页ZHANG Jin-lei TAN Xue-cai ZHAO Dan-dan TAN Sheng-wei LIU Li WANG Lin HUANG Zeng-wei; Supported by the National Natural Science Foundation of China(No.21065001);the Natural Science Foundation of Guangxi Province,China(Nos.0639025,0991084);the Support Program for 100 Young and Middle-aged Disciplinary Leaders in Higher Education Institutions of Guangxi Province,China(No.RC20060703005);the Project of Key Laboratory of Development and Application of Forest Chemicals of Guangxi Province,China(No.GXFC08-06);the Fund of Education Department of Guangxi Province,China(No.200812MS074); A novel type of Fe3O4 nanoparticles modified glass carbon electrode（Fe3O4/GCE） was constructed and the electrochemical properties of N-（4-nitro-2-phenoxyphenyl）methanesulfonamide（nimesulide） were studied on the ...; 关键词：Fe3O4 nanoparticle Modified electrode NIMESULIDE DETERMINATION Electrochemical behavior

In vitro-in vivo correlation study on nimesulide loaded hydroxypropylmethylcellulose microparticles: 《药学学报》2010年第6期772-777,共6页Shujaat Ali KHAN Mahmood AHMAD Ghulam MURTAZA Muhammad Naeem AAMIR Rozina KOUSAR Fatima RASOOL Shahiq-u-ZAMAN; Higher Education Commission of Pakistan for proving financial support for research.; This study involves mathematical simulation model such as in vitro-in vivo correlation(IVIVC) development for various extended release formulations of nimesulide loaded hydroxypropylmethylcellulose(HPMC) microparticle...; 关键词：NIMESULIDE MODELLING HPMC Wagner-Nelson method

A simple and robust HPLC-MS method for the quantitative determination of nimesulide in human plasma and its application to bioequivalence study in Chinese volunteers被引量：2: 《Journal of Chinese Pharmaceutical Sciences》2010年第5期379-386,共8页杨雯雯房丽娜郝桂彤刘丽霞杨红英孙立新; A rapid and sensitive high performance liquid chromatography-mass spectrometry （HPLC-MS） method for the quantification of nimesulide in human plasma was developed and validated. Sample aliquots of 100μL were extrac...; 关键词：NIMESULIDE HPLC-MS Quantification Human plasma BIOEQUIVALENCE

NIMESULIDE