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CELL-FREE: 作品数：148被引量：425H指数：12; 导出分析报告; 相关作者：冉静学孙强李秀军郭晓东侯朝晖更多>>; 相关机构：哈尔滨工业大学中国航天科工集团第四研究院北京机电工程总体设计部中央民族大学凯迪迪爱通信技术有限公司更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划北京市自然科学基金更多>>

Circulating cell-free mtDNA as a new biomarker for cancer detection and management: 《Cancer Biology & Medicine》2024年第2期105-110,共6页Fan Peng Siyuan Wang Zehui Feng Kaixiang Zhou Huanqin Zhang Xu Guo Jinliang Xing Yang Liu; the National Natural Science Foundation of China(Grant No.81830070)。; Cancer is a major cause of death worldwide,and was responsible for 19.29 million new cases and 9.96 million deaths in 2020 alone.The total number of patients with cancer worldwide is estimated to reach 28 million by 2...; 关键词：CANCER CANCER DEATH

Method for the extraction of circulating nucleic acids based on MOF reveals cell-free RNA signatures in liver cancer: 《National Science Review》2024年第1期89-101,共13页Yuqing Sun Haixin Yu Shaoqing Han Ruoxi Ran Ying Yang Yongling Tang Yuhao Wang Wenhao Zhang Heng Tang Boqiao Fu Boshi Fu Xiaocheng Weng Song-Mei Liu Hexiang Deng Shuang Peng Xiang Zhou; financially supported by the National Natural Science Foundation of China (92153303, 21721005 and 91940000to X.Z.;81772276 and 81902141 to S.L.);the National Science Foundation for Young Scientists of China (21907078 to S.P.);Hubei Provincial Innovation Group (2019CFA018 to S.L.)。; Cell-free RNA(cf RNA) allows assessment of health, status, and phenotype of a variety of human organs and is a potential biomarker to non-invasively diagnose numerous diseases. Nevertheless, there is a lack of highly ...; 关键词：MOF circulating cell-free RNA biomarker liver cancer diagnosis

Cell-free mitochondrial DNA quantification in ischemic stroke patients for non-invasive and real-time monitoring of disease status被引量：1: 《World Journal of Translational Medicine》2022年第2期14-28,共15页Nusrath Fathima Sandhya Manorenj Sandeep Kumar Vishwakarma Aleem Ahmed Khan; BACKGROUND Acute ischemic stroke(AIS)is one of the major causes of the continuous increasing rate of global mortality due to the lack of timely diagnosis,prognosis,and management.This study provides a primitive platfo...; 关键词：Cell-free mitochondrial DNA NADH-ubiquinone oxidoreductase chain 1 Ischemic stroke Circulating biomarker National Institute of Health Stroke Scale score Stroke assessment Severity and outcome

Circulating tumor DNA for diagnosis,prognosis and treatment of gastrointestinal malignancies被引量：1: 《World Journal of Clinical Oncology》2022年第6期473-484,共12页Patrick Kirchweger Helwig Valentin Wundsam Holger Rumpold; Minimally invasive detection of circulating tumor DNA(ctDNA)in peripheral blood or other body fluids of patients with gastrointestinal malignancies via liquid biopsy has emerged as a promising biomarker.This is urgent...; 关键词：Cell-free tumor DNA Circulating tumor DNA Gastrointestinal cancer Liquid biopsy Esophageal cancer Gastric cancer Liver cancer Bile duct cancer Pancreatic cancer Colorectal cancer

Circulating cell-free nucleic acids as prognostic and therapy predictive tools for metastatic castrate-resistant prostate cancer: 《World Journal of Clinical Oncology》2020年第7期450-463,共14页Navid Sobhani Marianna Sirico Daniele Generali Fabrizio Zanconati Bruna Scaggiante; Metastatic castrate-resistant prostate cancer remains a disease hard to cure,and for this reason predictive tools to monitor disease progression and therapy response are an urgent need.In this respect,liquid biopsy on...; 关键词：Metastatic castrate-resistant prostate cancer Circulating free deoxyribonucleic acid Cell-free tumor deoxyribonucleic acid Circulating free ribonucleic acid Liquid biopsy Prostate cancer

Liquid biopsy:expanding the frontier of circulating biomarker discovery and validation in breast cancer: 《Cancer Drug Resistance》2019年第4期1215-1223,共9页Philip CMiller Dorraya El-Ashry Marc ELippman; Our work referenced here was supported by funding from the Breast Cancer Research Foundation(BCRF16098),and by the Prevent Cancer Foundation(M1601095).; Liquid biopsies represent an attractive,minimally-invasive alternative to surgical sampling or complex imaging of breast cancer and breast cancer metastasis.Here we present a summary of the major biomarker components ...; 关键词：Liquid biopsy breast cancer cell-free tumor DNA CTC cancer associated fibroblast

The size of cell-free mitochondrial DNA in blood is inversely correlated with tumor burden in cancer patients被引量：6: 《Precision Clinical Medicine》2019年第3期131-139,共9页Qin An Youjin Hu Qingjiao Li Xufeng Chen Jiaoti Huang Matteo Pellegrini Xianghong Jasmine Zhou Matthew Rettig Guoping Fan; We would like to thank Dr.Anthony E.Sisk Jr.at UCLA Genitourinary Pathology Unit for histological analysis.This study is funded by National Institutes of Health(Grant No:RO1 DE DE025474,P50CA092131,and P50CA211015),and CIRM Stem Cell Genomics Centers of Excellence Award.; Circulating cell-free DNAs(cfDNAs)are fragmented DNA molecules released into the blood by cells.Previous studies have suggested that mitochondria-originated cfDNA fragments(mt-cfDNAs)in cancer patients are more fragme...; 关键词：circulating cell-free DNA(cfDNA) tumor burden cancer progression liquid biopsy

Circulating tumor cells and their role in prostate cancer被引量：1: 《Asian Journal of Andrology》2019年第1期24-31,共8页Moritz Maas Miriam Hegemann Steffen Rausch Jens Bedke Arnulf Stenzl Tilman Todenhofer; Circulating tumor cells (CTC)have become an important biomarker in patients with advanced prostate cancer.CTC count has been demonstrated to be a prognostic factor for overall survival in patients with metastatic cast...; 关键词：AR-V7 biomarker CELL-FREE DNA cfDNA CIRCULATING tumor cells CTDNA liquid BIOPSY PROSTATE cancer

Utility of cell-free nucleic acid and circulating tumor cell analyses in prostate cancer被引量：3: 《Asian Journal of Andrology》2018年第3期230-237,共8页Theodore Gourdin Guru Sonpavde; Prostate cancer is characterized by bone metastases and difficulty of objectively measuring disease burden. In this context, cell-free circulating tumor DNA （ctDNA） and circulating tumor cell （CTC） quantitation an...; 关键词：CIRCULATING circulating tumor DNA GENOMICS neoplastic cells prostatic neoplasms

Prognostic and predictive blood biomarkers in gastric cancer and the potential application of circulating tumor cells被引量：22: 《World Journal of Gastroenterology》2018年第21期2236-2246,共11页Ting-Ting Li Hao Liu Jiang Yu Guang-Yao Shi Li-Ying Zhao Guo-Xin Li; Supported by the Guangdong Provincial Natural Science Foundation,No.2016A030313843; Gastric cancer(GC), with its high incidence and mortality rates, is a highly fatal cancer that is common in East Asia particularly in China. Its recurrence and metastasis are the main causes of its poor prognosis. Cir...; 关键词：GASTRIC cancer BIOMARKER CIRCULATING tumor cells AUTOANTIBODIES CELL-FREE DNA

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