Background:Emerging data suggested that liquid biopsy such as detection of circulating tumor cells(CTCs)and cell-free tumor DNA analysis augments the management of patients with urothelial cancer(UC).We presented our ...
Minimally invasive detection of circulating tumor DNA(ctDNA)in peripheral blood or other body fluids of patients with gastrointestinal malignancies via liquid biopsy has emerged as a promising biomarker.This is urgent...
目的:比较Vangenes■Cell-Free DNA采血管和Streck■Cell-Free DNA 采血管对血液样品的运输保存效果.方法:通过静脉抽血, 18名志愿者分别使用Vangenes■Cell-Free DNA 采血管与Streck■Cell-Free DNA采血管各采集一管10mL血液.经过约50...
Cell-flee DNA (cfDNA) is small short double stranded molecule that is also found in seminal fluid. It is a product ofapoptotic cells in different developmental stages during spermatogenesis. To final concentration o...
supported by the Precision Medicine Research Program of the Chinese Academy of Sciences (Grant No. KJZD-EW-L14);the National Basic Research Program of China (973 Program; Grant Nos. 2012CB518302 and 2013CB911001);the National Natural Science Foundation of China (Grant Nos. 31540033 and 91019024);the Strategic Priority Research Program of the Chinese Academy of Sciences (Grant No. XDA01040407)
Detection of circulating tumor DNAs(ct DNAs) in cancer patients is an important component of cancer precision medicine ct DNAs. Compared to the traditional physical and biochemical methods, blood-based ct DNA detectio...
Gastrointestinal stromal tumors(GISTs) have been recognized as a biologically distinctive type of tumor,different from smooth muscle and neural tumors of the gastrointestinal tract.The identification of genetic aberra...
supported partly by the National Natural Science Foundation of China(No.81227901);the Natural Science Basic Research Plan in Shaanxi Province of China(No.2015JZ019);the Fundamental Research Funds for the Central Universities,National Cancer Institute of the National Institutes of Health(No.R00CA138914);National Natural Science Foundation(No. 81372216)
Cancer is a common cause of death worldwide.Despite significant advances in cancer treatments,the morbidity and mortality are still enormous.Tumor heterogeneity,especially intratumoral heterogeneity,is a significant r...
Background: Cell-free DNA (cfDNA) holds promise as a tumor marker of clinical importance. We aimed to investigate the prognostic value of baseline cfDNA in non small-cell lung cancer (NSCLC). Material and Methods: Dur...
National natural science funding(ID:30772069);CMB partial funding(2003)
Non-invasive prenatal gene diagnosis has been developed rapidly in the recent years, and numerous medical researchers are focusing on it. Such techniques could not only achieve prenatal diagnosis accurately, but also ...