NANODEVICE

作品数：25被引量：23H指数：3
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相关领域：一般工业技术理学更多>>
相关机构：密歇根州立大学更多>>
相关期刊：《National Science Review》《Science China(Information Sciences)》《International Journal of Extreme Manufacturing》《Science China Chemistry》更多>>
相关基金：国家自然科学基金北京市自然科学基金国家重点基础研究发展计划高等学校学科创新引智计划更多>>
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An epH-driven DNA nanodevice for impeding metastasis in vivo by selectively blocking cell signaling
《National Science Review》2025年第3期255-266,共12页Kun Yuan Hong-Min Meng Hongzhi Sun Lingbo Qu Zhaohui Li Weihong Tan 
supported by the Natural Science Foundation of Henan(232300421021 and 242300421121);the National Natural Science Foundation of China(22374136,22274143);Henan Fundamental Research Leading Talent,and the National Key Research and Development Program(2023YFF0714402 and 2023YFF0714400).
Invasion and metastasis dominate tumor progression,causing a substantial proportion of cancer-related deaths.However,the efficacy of current antimetastatic treatments is hampered by the dearth of targeted therapeutics...
关键词：antimetastatic therapy cellular signaling blockade DNA nanodevice extracellular pH tailored bioregulation 
An aptamer-driven DNA nanodevice for improved delivery of synthetic immunostimulants
《Nano Research》2024年第10期9078-9083,共6页Dejie Lu Zhenghan Di Lele Li Jian Zhao Li Zheng 
supported financially by the National Natural Science Foundation of China(Nos.T2322005 and 32101156);Youth Innovation Promotion Association CAS.
Efficient delivery of therapeutics to immune cells remains a formidable challenge for cancer immunotherapy.In this work,we demonstrate that an aptamer-driven DNA nanodevice,constructed through linkage of a synthetic i...
关键词：APTAMER immunostimulatory oligonucleotides DNA nanodevice tumor-associated macrophages cancer therapy 
Monitoring of Cell Membrane Microenvironment Based on DNA Nanodevices
《Chemical Research in Chinese Universities》2024年第2期255-267,共13页NAN Hexin CAI Ming KUANG Shi NIE Zhou 
supported by the National Key Research and Development Program of China(Nos.2021YFA0910100,2020YFA0907500);the National Natural Science Foundation of China(Nos.22034002,92253304).
The cell membrane is a critical barrier for cellular homeostasis,integral to signaling and intercellular communication,and vital for understanding cellular functions and disease mechanisms.Investigating its microenvir...
关键词：DNA nanodevice Cell membrane Cellular micro-environment MONITORING 
An AND-Gate DNA Nanodevice for Dual Protein-Mediated,Tumor-Specific Imaging
《Chinese Journal of Chemistry》2023年第12期1437-1442,共6页Zetan Fan Fangzhi Yu Mingming Yu Lele Li 
financially supported by the Beijing Natural Science Foundation(JQ20005).
Sensitive and specific imaging of tumor-associated biomarkers offers an effective way for cancer diagnosis.However,most of the reported imaging probes are limited to the targeting of a single biomarker,which may impai...
关键词：APTAMER DNA nanodevice Protein Sensor BIOIMAGING 
A DNA Nanodevice for Cancer Vaccination
《Chemical Research in Chinese Universities》2020年第6期1147-1148,共2页ZUO Hua MAO Chengde 
To realize effective cancer immunotherapy,Ding et al.constructed a structurally well-defined DNA-based nanodevice to quantitatively assemble cancer cell-specific antigen and multiple adjuvants as a cancer vaccine.This...
关键词：VACCINE al. CANCER 
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