a grant from the Special Medicine Innovation Scientific Special Project(No.2018ZX09733003)。
Multiple myeloma(MM)is a blood malignancy characterized by the clonal proliferation of plasma cells,which increases the number of monoclonal immunoglobulins in blood and urine and causes target organ damage.Long non-c...
supported by grant from the Beijing Natural Science Foundation(No.7082098).
To the Editor:Ovarian cancer is the leading cause of death from gynecologic malignancies.The major limitation to the successful long-term treatment of ovarian cancer is the development of chemotherapeutic resistance,w...
This study was supported by grants from the National Key R&D Program of China (No. 2017YFC1001200) and National Natural Science Foundation of China (No. 81270681 ).
Background: Endometriosis is a challenging disease with symptoms such as dysmenorrhea and infertility. However, its etiology is still vague and there is still no effective markers or treatment. This study aimed to pr...
This work was supported by grants from the National Natural Science Foundation of China (No. 81672882 and No. 81502441) and Science and Technology Support Program of Sichuan Province (No. 2017SZ0003).
Background: MicroRNAs (miRNAs) have been reported to play vital roles in liver regeneration. Previous studies mainly focused on the functions of intracellular miRNAs, while the functions of circulating exosomal miR...
Background:Nucleolin (NCL) is the most abundant RNA-binding protein in the cell nucleolus and plays an important role in chromatin stability,ribosome assembly,ribosomal RNA maturation,ribosomal DNA transcription,nu...
Background: At present, a diagnostic tool with high specificity for impaired endometrial receptivity, which may lead to implantation failure, remains to be developed. We aimed to assess the different endometrial micr...
Source of Support: This work was supported by the National Natural Science Foundation of China (No. 81170732 and No.81100561 ).
Background:Hypertension often persists after adrenalectomy for primary aldosteronism (PA).Many studies have analyzed the outcomes of adrenalectomy for aldosterone-producing adenomas (APA) to identify predictive f...
This study was supported by grants from the National Natural Science Foundation of China (No.81160143) and Xinjiang Uygur Autonomous Region Science and Technology Supporting Project in Xinjiang(No.201191162).
Parkinson's disease (PD), a complex neurodegenerative disease, is characterized by the loss of dopamine neurons in the substantia nigra ot the midbraln. PD patients have varying degrees of cognitive impairment (CI...
The combination of intracytoplasmic sperm injection (ICSI) with artificial oocyte activation has overcome repeated fertilization failure after ICSI due to sperm defects in activating oocyte, resulting in pregnancies...
This study was supported by grants from the Key Research Project from Shandong Science and Technology Commission (No. 2011GSF 11846) and the National Youthful Science Foundation of China (No. 81101858).
Background Heme oxygenase-1 (HO-1) can be induced by inflammatory cytokines,oxidation,ischemia,hypoxia,and endotoxins.As a "graft survival protective gene," HO-1 is a hot spot in organ transplantation research.How...