MICROARRAY

作品数：440被引量：1533H指数：15
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Comparing gene expression profiles of Kashin-Beck and Keshan diseases occurring within the same endemic areas of China
《Science China(Life Sciences)》2013年第9期797-803,共7页WANG Xi WANG Shuang HE ShuLan ZHANG Feng TAN WuHong LEI YanXia YU HanJie LI Zheng NING YuJie XIANG YouZhang GUO Xiong 
supported in part by the Key Scientific and Technological Innovation Special Projects of Shaanxi "13115" of China (2009ZDKG-79);the National Natural Science Foundation of China (30872192, 81273008)
In this study, differentially expressed genes in peripheral blood from patients with Kashin-Beck disease and Keshan disease were compared to further investigate the etiology and pathogenesis of both diseases, which oc...
关键词：Kashin-Beck disease Keshan disease MICROARRAY peripheral blood mononuclear cells common environmental factors differential gene expression 
Pathways related to mitochondrial dysfunction in cartilage of endemic osteoarthritis patients in China被引量：1
《Science China(Life Sciences)》2012年第12期1057-1063,共7页LI ChunYan WANG WeiZhuo GUO Xlong ZHANG Feng MA WeiJuan ZHANG YinGang LI YouFen BAI YiDong LAMMI Mikko J 
supported in part by the National Natural Science Foundation of China (Grant No. 30972556);the Key Scientific and Technological Innovation Special Projects of Shaanxi "13115" of China (Grant No. 2009ZDKG-79);the Specialized Research Fund for the Doctoral Program of Higher Education of China (Grant No. 20090201110049)
In this paper, we present the first evidence of differences in the mitochondria-related gene expression profiles of adult articular cartilage derived from patients with Kashin-Beck disease and normal controls. The exp...
关键词：Kashin-Beck disease MICROARRAY mitochondrial dysfunction IPA analysis 
The miRNA expression profile of the uveal melanoma被引量：17
《Science China(Life Sciences)》2011年第4期351-358,共8页YANG ChengHsun 
supported by the Beijing Municipal Natural Science Foundation(Grant Nos.7092021 and 7072019);the Beijing Science and Technology Support(Grant No.Z08050703080882);the National Natural Science Foundation of China(Grant No.30571988)
The miRNA expression profile was initially established to investigate its corresponding function in human uveal melanoma. The miRNA expression profile in human uveal melanoma was analyzed by a micro chip technique.The...
关键词：uveal melanoma MIRNA microRNA microarray target gene TUMORIGENESIS 
A web-based platform for rice microarray annotation and data analysis
《Science China(Life Sciences)》2010年第12期1467-1473,共7页CHEN DiJun ZHANG Fan YUAN ChunHui LU Jing LI Xia CHEN Ming 
supported by the National Natural Science Foundation of China (Grant Nos. 30600367 and 30771326);the National High-Tech Research and Development Program of China (Grant No. 2007AA02Z329);the National Basic Research Program of China (Grant Nos. 2007AA02Z329 and 2008AA10Z125);Heilongjiang Science & Technology Key Project (Grant No. 2008CB517302)
Rice(Oryza sativa) feeds over half of the global population.A web-based integrated platform for rice microarray annotation and data analysis in various biological contexts is presented,which provides a convenient quer...
关键词：RICE MICROARRAY ANNOTATION data analysis 
AtMYB103 is a crucial regulator of several pathways affecting Arabidopsis anther development被引量：12
《Science China(Life Sciences)》2010年第9期1112-1122,共11页ZHU Jun ZHANG GuoQiang CHANG YuHua LI XiaoChuan YANG Jun HUANG XueYong YU QingBo CHEN Hui WU TianLong YANG ZhongNan 
supported by the National Natural Science Foundation of China (Grant No. 30925007);the National Basic Research Program of China (Grant No. 2007CB947600)
Previous reports indicated that AtMYB103 has an important role in tapetum development,callose dissolution,and exine formation in A.thaliana anthers.Here,we further characterized its function in anther development by e...
关键词：ARABIDOPSIS AtMYB103 tapetum development transcription factor MICROARRAY 
Progress in the detection of human genome structural variations被引量：1
《Science China(Life Sciences)》2009年第6期560-567,共8页WU XueMei1,3 & XIAO HuaSheng1,2 1 Center of Functional Genomics,Key Laboratory of System Biology,Shanghai Institutes for Biological Sciences,Chinese Academy of Sciences,Shanghai 200031,China 2 National Engineering Center for Biochip at Shanghai,Shanghai 201203,China 3 Graduate School of the Chinese Academy of Sciences,Shanghai 200031,China 
Supported by the National High Technology Research and Development Program of China (Grant No. 2006AA020704)
The emerging of high-throughput and high-resolution genomic technologies led to the detection of submicroscopic variants ranging from 1 kb to 3 Mb in the human genome.These variants include copy number variations(CNVs...
关键词：structural variation CYTOGENETIC MICROARRAY PCR paired end mapping(PEM) next-generation SEQUENCING 
Perspectives of DNA microarray and next-generation DNA sequencing technologies被引量：15
《Science China(Life Sciences)》2009年第1期7-16,共10页TENG XiaoKun1 & XIAO HuaSheng1,2 1 National Engineering Center for Biochip at Shanghai,Shanghai 201203,China 2 Shanghai-MOST Key Laboratory of Health and Disease Genomics,Chinese National Human Genome Center,Shanghai 201203,China 
Supported by the National High-Tech Research Program of China (Grant No.2006AA020704);Shanghai Science and Technology Commission (Grant No.05DZ22201)
DNA microarray and next-generation DNA sequencing technologies are important tools for high-throughput genome research,in revealing both the structural and functional characteristics of genomes.In the past decade the ...
关键词：DNA MICROARRAY next generation DNA SEQUENCING GENOME 
Expression profiling analysis for genes related to meat quality and carcass traits during postnatal development of backfat in two pig breeds被引量：1
《Science China(Life Sciences)》2008年第8期718-733,共16页LI MingZhou1, ZHU Li1, LI XueWei1, SHUAI SuRong1, TENG XiaoKun2, XIAO HuaSheng2, LI Qiang1, CHEN Lei1, GUO YuJiao1 & WANG JinYong3 
the Program for Changjiang Scholars and Innovative Research Team in University of Chinese Ministry of Education (Grant No. IRT0555-6);Specialized Research Fund for the Doctoral Program of Higher Education of China (Grant No. 20060626003);National Sci &Tech Support Program (Grant No. 2007BAD51B03);Project of Provincial Eleventh 5 Years’Animal Breeding of Sichuan Province (Grant No. 2006YZGG-15);Specialized Research Fund of Chinese Ministry of Agri-culture (Grant No. NYHYZX07-034)
The competitive equilibrium of fatty acid biosynthesis and oxidation in vivo determines porcine sub-cutaneous fat thickness(SFT) and intramuscular fat(IMF) content.Obese and lean-type pig breeds show obvious differenc...
关键词：PIG ADIPOSE MICROARRAY differential GENE expression clustering ANALYSIS GENE regulatory network(GRN) 
Gene expression profile in immunologically injured liver cell of mice被引量：3
《Science China(Life Sciences)》2006年第5期454-459,共6页HAN Fengmei CHENG Ming XIA Qisong CHEN Yong 
To study the gene expression profiles between immunologically injured liver cell and normal liver cell of mice and to screen on a large scale the differentially expressed genes associated with the formation of liver i...
关键词：mouse  IMMUNOLOGICAL LIVER damage  cDNA microarray  gene expression profile. 
Construction, detection and microarray analysis on Shigella dysenteriae A1 IroN, ShuA single, double mutants被引量：1
《Science China(Life Sciences)》2006年第3期251-258,共8页BIN Wen, LIU Moqing, PENG Junping, SUN Lilian, XU Xingye, ZHANG Jinghai& JIN Qi Shengyang Pharmaceutical University, School of Pharmaceutical Engineering, Shengyang 110016, China State Key Laboratory for Molecular Virology and Genetic Engineering, Beijing 100176, China 
In this study, we constructed single mutants MTS-1, MTS-2 of IroN and ShuA gene and double mutant MTS of them in Shigella dysenteriae A1 strain 51197 by insert and absence. The functional detection of every mutant was...
关键词：SHIGELLA dysenteriae A1  gene knockout  functional detection  MICROARRAY analysis. 
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