相关期刊:《South China Journal of Cardiology》《World Journal of Experimental Medicine》《World Journal of Gastroenterology》《World Journal of Emergency Medicine》更多>>
Paraoxonase-1(PON-1)is an enzyme that hydrolyzes organophosphate pesticides.The presence of polymorphisms in PON-1(L55M and Q192R)decreases its enzyme activity and increases the risk of central nervous system(CNS)toxi...
Paraoxonase-1(PON1)is an important enzyme in various pathologies such as pesticide poisoning,diabetes,atherosclerosis,neuronal disorders,and cancer,due to its multifunctional activity since it acts on different metabo...
BACKGROUND: The effect of increased oxidative stress on the development of chronic obstructive pulmonary disease(COPD) is well known. One of the antioxidative systems against oxidative stress in human body is paraoxon...
Supported by Instituto de Salud CarlosⅢ,No.PI08/1381,and No.PI11/00130;Carlos Ⅲ Health Institute,Madrid,Spain;the Fondo Europeo de Desarrollo Regional
The incidence and prevalence of non-alcoholic fatty liver disease(NAFLD)is constantly increasing.Despite this is apparently associated with the growing increase in obesity,insulin resistance and obesity-related metabo...
Supported by Atatrk University Scientific Research Project Fund(BAP-2009/81)
Objective:To investigate the in vitro effects of the antihacterial drugs,mcropenem trihydrate.piperacillin sodium,and cefoperazone sodium,on the activity of human serum paraoxonase mPOND.Methods:hPQN1 was purified fro...
supported by grants from The National Natural Science Foundation of China(81200985,81071005);Natural Science Foundation of Hunan Province,China(11JJ3117);the Scientific Research Foundation for the Returned Overseas Chinese Scholars,State Education Ministry(2011508)~~
Patients with type 2 diabetes mellitus(T2DM) frequently exhibit macrovascular complications of atherosclerotic cardiovascular(CV) disease. High density lipoproteins(HDL) are protective against atherosclerosis. Low lev...
Project(Nos.PW 55/09 and DS 41/10) supported by the Department of Laboratory Diagnostics,Medical University of Lublin,Poland
Disturbances in the metabolism of lipoprotein profiles and oxidative stress in hemodialyzed (HD) and post-renal transplant (Tx) patients are proatherogenic, but elevated concentrations of plasma high-density lipop...
supported by 2009 Shenzhen Health Bureau research project(200903204)
Repeat coronary revascularizations (RCR) are common in patients underwent percutaneous coronary intervention.There is no available prediction model for RCR at present.The association between paraoxonas-1 (PON1) and th...