PARAOXONASE-1

作品数:12被引量:18H指数:3
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相关领域:医药卫生更多>>
相关作者:徐霖陈容前杨杰周俊山邹建军更多>>
相关机构:南华大学贵阳学院南京医科大学贵州大学更多>>
相关期刊:《South China Journal of Cardiology》《World Journal of Experimental Medicine》《World Journal of Gastroenterology》《World Journal of Emergency Medicine》更多>>
相关基金:国家自然科学基金贵州省自然科学基金更多>>
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Relationship between PON-1 enzymatic activity and risk factors for pesticide poisoning in farmers from the Cienega,Jalisco,Mexico
《BIOCELL》2021年第5期1241-1250,共10页HAZAEL RAMIRO CEJA-GALVEZ ERANDIS DHENI TORRES-SÁNCHEZ JUAN HERIBERTO TORRES-JASSO EMMANUEL REYESURIBE JOEL SALAZAR-FLORES 
Paraoxonase-1(PON-1)is an enzyme that hydrolyzes organophosphate pesticides.The presence of polymorphisms in PON-1(L55M and Q192R)decreases its enzyme activity and increases the risk of central nervous system(CNS)toxi...
关键词:PARAOXONASE-1 PESTICIDES Organophosphates POLYMORPHISMS 
Effect of structure and function of paraoxonase-1(PON-1)on organophosphate pesticides metabolism被引量:2
《BIOCELL》2020年第3期363-370,共8页HAZAEL RAMIRO CEJA-GÁLVEZ ERANDIS DHENI TORRES-SÁNCHEZ JUAN HERIBERTO TORRES-JASSO ARTURO VILLALOBOS ORNELAS JOEL SALAZAR-FLORES 
Paraoxonase-1(PON1)is an important enzyme in various pathologies such as pesticide poisoning,diabetes,atherosclerosis,neuronal disorders,and cancer,due to its multifunctional activity since it acts on different metabo...
关键词:PON1 PESTICIDES ORGANOPHOSPHORUS TOXICITY 
Paraoxonase-1 gene in patients with chronic obstructive pulmonary disease investigation Q192R and L55M polymorphisms被引量:1
《World Journal of Emergency Medicine》2015年第3期201-206,共6页?ükrü Gürbüz Mustafa Y?ld?z Murat Kara Kür?at Kargün Mehtap Gürger Metin Ate??elik ?mer Do?an Alata? 
BACKGROUND: The effect of increased oxidative stress on the development of chronic obstructive pulmonary disease(COPD) is well known. One of the antioxidative systems against oxidative stress in human body is paraoxon...
关键词:Chronic obstructive pulmonary disease PARAOXONASE POLYMORPHISM Acute attack 
Chemokine ligand 2 and paraoxonase-1 in non-alcoholic fatty liver disease:The search for alternative causative factors被引量:4
《World Journal of Gastroenterology》2015年第10期2875-2882,共8页Jordi Camps Jorge Joven 
Supported by Instituto de Salud CarlosⅢ,No.PI08/1381,and No.PI11/00130;Carlos Ⅲ Health Institute,Madrid,Spain;the Fondo Europeo de Desarrollo Regional
The incidence and prevalence of non-alcoholic fatty liver disease(NAFLD)is constantly increasing.Despite this is apparently associated with the growing increase in obesity,insulin resistance and obesity-related metabo...
关键词:Biomarkers CYTOKINES Inflammation METABOLISM Mitoc 
Impact of antibacterial drugs on human serum paraoxonase-1(hPON1)activity:an in vitro study
《Asian Pacific Journal of Tropical Biomedicine》2014年第8期603-609,共7页Hakan Syt Elif Duygu Kaya Skr Beydemir 
Supported by Atatrk University Scientific Research Project Fund(BAP-2009/81)
Objective:To investigate the in vitro effects of the antihacterial drugs,mcropenem trihydrate.piperacillin sodium,and cefoperazone sodium,on the activity of human serum paraoxonase mPOND.Methods:hPQN1 was purified fro...
关键词:PARAOXONASE Inhibition MEROPENEM trihydrate PIPERACILLIN SODIUM CEFOPERAZONE SODIUM 
Paraoxonase-1介导硫化氢的抗甲醛神经毒性作用(英文)
《生物化学与生物物理进展》2014年第5期487-496,共10页张平 李祥 任衍开 王春燕 邹伟 唐小卿 
supported by grants from The National Natural Science Foundation of China(81200985,81071005);Natural Science Foundation of Hunan Province,China(11JJ3117);the Scientific Research Foundation for the Returned Overseas Chinese Scholars,State Education Ministry(2011508)~~
我们以往的研究工作证实了硫化氢(hydrogen sulfide,H2S)对甲醛神经毒性和氧化应激具有拮抗作用.Paraoxonase-1(PON-1)是机体重要的内源性抗氧化剂.本研究的目的是探讨PON-1是否可介导H2S的抗甲醛神经毒性作用.采用甲醛损伤PC12细胞为...
关键词:甲醛 硫化氢 PARAOXONASE-1 凋亡 活性氧 
High density lipoproteins and type 2 diabetes:Emerging concepts in their relationship被引量:3
《World Journal of Experimental Medicine》2014年第1期1-6,共6页Michael S Kostapanos Moses S Elisaf 
Patients with type 2 diabetes mellitus(T2DM) frequently exhibit macrovascular complications of atherosclerotic cardiovascular(CV) disease. High density lipoproteins(HDL) are protective against atherosclerosis. Low lev...
关键词:Type 2 DIABETES High density LIPOPROTEINS INSULIN SECRETION βcells PARAOXONASE-1 
对氧磷酶1参与香猪高脂模型脂质代谢研究
《湖北农业科学》2012年第7期1404-1406,共3页徐霖 李升 冉雪琴 王嘉福 
贵州省自然科学基金项目(20082129);贵州省教育厅培育项目(黔教科2007-001);贵阳学院青年课题基金项目(贵阳学院2008)
猪动脉粥样硬化形成过程和解剖特征与人极为相似,为研究动脉粥样硬化发病机理,建立了贵州小香猪高脂模型,并设了对照组。通过饲养试验,测定猪动脉粥样硬化形成过程中与脂质代谢密切相关的4种关键因子,即血清总胆固醇(Total cholesterol,...
关键词:动脉粥样硬化(Atherosclerotic AS) 对氧磷酶1(Paraoxonase-1) 脂质代谢 香猪 高脂模型 
Association between moderately oxidized low-density lipoprotein and high-density lipoprotein particle subclass distribution in hemodialyzed and post-renal transplant patients被引量:5
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2011年第5期365-371,共7页Elzbieta KIMAK Magdalena HALABI Iwona BARANOWICZ-GASZCZYK Janusz SOLSKI Andrzej KSIAZEK 
Project(Nos.PW 55/09 and DS 41/10) supported by the Department of Laboratory Diagnostics,Medical University of Lublin,Poland
Disturbances in the metabolism of lipoprotein profiles and oxidative stress in hemodialyzed (HD) and post-renal transplant (Tx) patients are proatherogenic, but elevated concentrations of plasma high-density lipop...
关键词:Lipids LIPOPROTEINS Paraoxonase-1 (PON-1) activity Oxidized low-density lipoprotein (ox-LDL) High-density lipoprotein (HDL) particles Post-renal transplant HEMODIALYSIS 
Association between serum paraoxonase-1 activity level and repeat coronary revascularizations
《South China Journal of Cardiology》2010年第2期93-95,100,共4页吴剑胜 陈晓燕 魏文斌 张新霞 胡雪松 吴曾繁 
supported by 2009 Shenzhen Health Bureau research project(200903204)
Repeat coronary revascularizations (RCR) are common in patients underwent percutaneous coronary intervention.There is no available prediction model for RCR at present.The association between paraoxonas-1 (PON1) and th...
关键词:PARAOXONASE coronary heart disease coronary revascularization 
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