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EPITOPES: 作品数：96被引量：141H指数：7; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：郭礼和费俭夏国宏邢力叶欣更多>>; 相关机构：中国科学院上海生命科学研究院郑州大学南昌大学广州血液中心更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金World Health Organization国家重点基础研究发展计划中国博士后科学基金更多>>

Antigen epitopes of animal coronaviruses:a mini-review: 《Animal Diseases》2024年第1期19-26,共8页Mingjun Su Guanghui Zheng Xiangwen Xu Houhui Song; supported by the Natural Science Foundation of Zhejiang Province(Q23C180006);the Zhejiang A&F University Talent Initiative Project(118-203402005901).; Coronaviruses are widespread in nature and can infect mammals and poultry,making them a public health concern.Globally,prevention and control of emerging and re-emerging animal coronaviruses is a great challenge.The m...; 关键词：Animal coronavirus Antigen epitope B-cell epitope T-cell epitope Immune responses Vaccines

Purification and immunoglobulin E epitopes identification of low molecular weight glutenin:an allergen in Chinese wheat: 《Food Science and Human Wellness》2023年第3期720-727,共8页Yanbo Wang Yihang Tong Jinru Zhou Dong Yang Linglin Fu; financially supported by the State Key Research and Development Plan(2019YFC1605002)。; As one of the most important cereals,wheat(Triticum aestivum)has high nutritional value and is widely cultivated in China.However,wheat can cause severe allergic reactions,and a growing number of people are developing...; 关键词：Triticum aestivum ALLERGEN Low molecular weight glutenin(LMW-GS) Immunological tools

Identification of two novel linear epitopes on the p30 protein of African swine fever virus: 《Journal of Integrative Agriculture》2023年第6期1945-1949,共5页YU Si-hui SHAN Zhao-meng YANG Jing-jing LIU Yi-ning WU Chang-de ZHANG Zhen-jiang ZHU Yuan-mao MENG Bo ZHAN Jia-xing WEN Xue-xia ZHANG Ying; supported by the National Natural Science Foundation of China (31902258);the Scientific Research Staring Foundation for the Doctors from the Science and Technology Department of Liaoning Province, China (2019-BS-204);the Major Project of Science and Technology of Liaoning Province (2020JH1/10200003)。; African swine fever(ASF) is a hemorrhagic disease caused by African swine fever virus(ASFV), which belongs to the Asfarviridae family. ASF has become prevalent in Africa since it was first reported in Kenya in 1921(Ro...; 关键词：AFRICAN continued SPREAD

ASFV pp62 Protein Has 9 Dominant B-T Cell Combined Epitopes被引量：2: 《Animal Husbandry and Feed Science》2022年第4期13-20,共8页Cao Qianda Dai Bihong Yang Yang Cao Xuelian; [Objective]The paper was to study the basic characteristics of the pp62 protein of the African swine fever virus strain Pig/HLJ/2018,and to provide more basic data for the study of the virus.[Method]We used the ProtPa...; 关键词：African swine fever virus pp62 CP530R Dominant B-T cell combined epitope Phylogenetic tree Visual analysis

Generation and application of two monoclonal antibodies targeting conserved linear epitopes in the NP protein of influenza A virus被引量：2: 《Journal of Integrative Agriculture》2022年第7期2095-2105,共11页ZHAO Yu-hui WEN Xia LI Qi-bing JIANG Li WANG Guang-wen LIANG Li-bin WANG Xiu-rong CHEN Hua-lan LI Cheng-jun; supported by the Natural Science Foundation of Heilongjiang Province,China(JQ2019C005);the National Natural Science Foundation of China(31702265 and 32172847)。; Monoclonal antibodies(mAbs) are widely used in virus research and disease diagnosis. The nucleoprotein(NP) of influenza A virus(IAV) plays important roles in multiple stages of the virus life cycle. Therefore, generat...; 关键词：influenza A virus NUCLEOPROTEIN monoclonal antibody application

Generation of Monoclonal Antibody to Porcine Reproductive and Respiratory Syndrome Virus GP4 Protein and Identification of Its Minic Epitopes: 《Journal of Northeast Agricultural University(English Edition)》2019年第2期49-59,共11页Liu Peng Yuan Qing Li Wei-qun Yin Xue-ting Ghulam Abbas Li Peng-chong Zhang Chao-fan Huang Xiao-dan Zhang Rui-li Li Guang-xing; Supported by the National Natural Science Foundation of China(31372438,31200122); Porcine reproductive and respiratory syndrome virus(PRRSV)GP4 protein was prokaryotically expressed,and used as an antigen to immunize six-week-old BALB/c female mice.With conventional cell fusion method,an anti-PRRSV...; 关键词：porcine REPRODUCTIVE and respiratory syndrome virus(PRRSV) GP4 protein MONOCLONAL antibody PHAGE display technique VIRAL infection

Elimination of murine and human T-cell epitopes in recombinant immunotoxin eliminates neutralizing and anti-drug antibodies in vivo被引量：1: 《Cellular & Molecular Immunology》2017年第5期432-442,共11页Ronit Mazor Devorah Crown Selamawit Addissie Youjin Jang Gilad Kaplan Ira Pastan; Antibodies against the toxin portion of recombinant immunotoxins （RIT） reduce their efficacy and pose a potential safety risk. To overcome this problem we mutated the very immunogenic immunotoxin SSIP to produce LMB...; 关键词：anti-drug antibodies deimmunization IMMUNOGENICITY mouse epitopes T-cell epitopes

Expression of Pseudorabies Virus gE Core Epitopes in Escherichia coli Strain BL21 and Utilization of Indirect PRV gE-ELISA被引量：2: 《Agricultural Biotechnology》2014年第4期39-44,共6页Guangjun GUO Sufang LU Guanggang QU Feng LI Lin DONG Yanli BI Jinliang WANG Feng WEI Na TANG Chunling ZHANG Zhuang DING Zhiqiang SHEN; Supported by Shandong Provincial Natural Science Foundation of China(ZR2012CQ012);Shandong Provincial Technical Innovation Grant of China(201220916006); Pseudorabies virus glycoprotein E （PRV gE） has been recognized as a suitable diagnostic antigen for pseudorabies. In order to produce gE antigen in large quantities and at low cost, a gene fragment encoding PRV gE c...; 关键词：Pseudorabies virus Glycoprotein E PRV strain SA Gene expression ELISA

The identification of potentially pathogenic and therapeutic epitopes from common human allergens: 《世界最新医学信息文摘》2014年第3期1-4,F0003,共5页; 关键词：过敏原抗原决定簇识别治疗性致病人类 T细胞表位免疫治疗

Identification of the Epitopes of Monoclonal Antibodies against P74 of Helicoverpa armigera Nucleopolyhedrovirus: 《Virologica Sinica》2013年第6期360-367,共8页Limin Liao Dianhai Hou Huachao Huang Manli Wang Fei Deng Hualin Wang Zhihong Hu Tao Zhang; supported by the National Science Foundation of China(31130058 to Z.H.).Monoclonal Antibodies against HearNPV P74; P74 is a per os infectivity factor of baculovirus.Here,we report the production of three monoclonal antibodies (mAbs),denoted as 20D9,20F9 and 21E1,raised against P74 of Helicoverpa armigera nucleopolyhedrovirus (Hear...; 关键词：HEARNPV P74 Linear epitope Monoclonal antibody

EPITOPES