PHENYLACETATE

作品数:12被引量:21H指数:2
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相关领域:医药卫生更多>>
相关作者:李路军更多>>
相关机构:湖北大学UCL商业有限公司生物化学系更多>>
相关期刊:《天然产物研究与开发》《Chemical Research in Chinese Universities》《Chinese Journal of Cancer Research》《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》更多>>
相关基金:国家自然科学基金广东省自然科学基金深圳市基础研究计划项目国家科技攻关计划更多>>
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Synthesis,Crystal Structure and DFT Calculation of 2-Methoxyimino Phenylacetate Derivatives Containing 1,3,4-Oxadiazole Ring被引量:1
《Chinese Journal of Structural Chemistry》2021年第12期1647-1654,1554,共9页REN Hui-Dong LI Kang-Ming YI Yang-Jie WANG Man YE Jiao HU Ai-Xi CHEN Yun OU Xiao-Ming LI Jian-Ming 
This project was supported by the National Key R&D Program of China(No.2016YFD0300708)。
Four novel 2-methoxyimino phenylacetate derivatives containing 1,3,4-oxadiazole ring were designed and synthesized from the key intermediate of Trifloxystrobin or Azoxystrobin via intermediate derivatization and activ...
关键词:2-methoxyimino phenylacetate derivatives SYNTHESIS crystal structure fungicidal activities DFT calculation 
彩云木叶化学成分及其抗炎活性研究被引量:1
《天然产物研究与开发》2020年第10期1698-1703,共6页阳航 邹情雅 陈宇 路艳霞 刘梦元 李路军 PaulW.Paré 
国家自然科学基金(81560703);深圳市基础研究计划自由探索项目(JCYJ20170306171157738);药物高通量筛选技术国家地方联合工程研究中心开放基金(M20181007);药学“荆楚卓越人才”协同育人计划大学生创新训练计划(M20191002)。
为研究彩云木Synadenium grantii叶的化学成分及部分化合物体外抗炎活性,本研究采用硅胶、Sephadex LH-20等多种柱色谱进行分离纯化,通过理化性质和NMR等波谱数据鉴定化合物的结构,并对部分化合物进行抑制脂多糖诱导RAW 264.7细胞释放N...
关键词:彩云木 化学成分 ingol-7 8 12-triacetate 3-phenylacetate 抗炎活性 
Phenylacetylglutaminate and Phenylacetate in Combination Upregulate VDUP1, Cause Cell Cycle Blockade and Apoptosis in U87 Glioblastoma Cells
《Journal of Cancer Therapy》2012年第3期192-200,共9页Sonali S. Patil Stanislaw R. Burzynski Emilia Mrowczynski Krzysztof Grela Sridar V. Chittur 
Phenylacetylglutaminate (PG) and Phenylacetate (PN) are metabolites of Phenylbutyrate (PB) and are constituents of antineoplaston AS2-1. These are sodium salts of amino acid derivative and carboxylic acid that inhibit...
关键词:GLIOBLASTOMA VDUP1 Phenylacetylglutaminate PHENYLACETATE APOPTOSIS Drug COMBINATION 
Treatment of Esthesioneuroblastoma and Nonsmall Cell Lung Cancer with Phenylbutyrate
《Journal of Cancer Therapy》2011年第4期518-522,共5页Stanislaw R. Burzynski Eva Nagy-Kubove 
Esthesioneuroblastoma is a malignant tumor, arising in the upper nasal cavity, that could spread to the frontal lobe of the brain as well as metastasize to the lymph nodes. Due to the low incidence of this tumor, FDA-...
关键词:PHENYLBUTYRATE ESTHESIONEUROBLASTOMA OLFACTORY NEUROBLASTOMA Nonsmall Cell LUNG Cancer PHENYLACETATE 
Correlation of serum arylesterase activity on phenylacetate estimated by the integrated method to common classical biochemical indexes of liver damage
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2007年第4期237-241,共5页LIAO Fei ZHU Xiao-yun WANG Yong-mei ZHAO Yun-sheng ZHU Lian-ping ZUO Yu-ping 
Project (No. 30200266) supported by the National Natural Science Foundation of China
The correlation of serum arylesterase(PON1) activity on phenylacetate determined by an integrated method to clas-sical biochemical indexes of liver damage was investigated for the use of PON1 activity to evaluate live...
关键词:ARYLESTERASE ALBUMIN Alanine aminotransferase Liver damage Ratio of albumin to globulins Integrated method BILIRUBIN 
Effects of Phenylacetate on Cell Proliferation and Homeobox Genes Expression in the HCT-8 Colorectal Carcinoma Cell Line
《Chemical Research in Chinese Universities》2006年第2期239-241,共3页ZHANG Yan REN Hui FANG Xue-dong TIAN Yu 
SupportedbytheNationalNaturalFoundationofChina(Nos.39900152and30271334)andtheFundofScienceandTechnologyDepartmentofJilinProvince(No.200506161).
To study the effects of phenylacetate (PA) on cell proliferation and homeobox (HOX) genes expression in the colorectal carcinoma HCT-8 cell line, HCT-8 cells were grown in the presence or absence of PA. The cellul...
关键词:PHENYLACETATE Colorectal carcinoma Homeobox gene 
Phenylacetate Down-regulates Expression of RNA Editing Deaminase ADAR2 mRNA in U-251MG Glioma Cells
《Chinese Journal of Clinical Oncology》2006年第1期1-4,共4页Yu Tian Yuzuo Pan Yufei Gao Guilin Li Jun Gao Xingli Zhao Guiying Li Renzhi Wang 
This study was supported by the National Nature Science Foundation of China (No. 30271334).
OBJECTIVE To observe the effect of phenylacetate on the expression of RNA editing deaminase ADAR2 mRNA in glioma cells. METHODS Primary glial cells from human brain tissue and glioma U-251MG cells were cultured. The e...
关键词:GLIOMA ADAR2 RT-PCR. 
THE EFFECT OF PHENYLACETATE ON THE EXPANSION AND CYTOTOXIC ACTIVITY OF ADHERENT LAK CELLS FROM PATIENTS WITH HEPATOCELLULAR CARCINOMA
《Chinese Journal of Cancer Research》2002年第1期1-4,共4页郑宁 叶胜龙 孙瑞霞 赵燕 汤钊猷 
This work was supported by a grant from the National 9th Five-Year Program of China (No. 96-906-01-20).
Objective: To improve the preparation of adherent lymphokine-activated killer (A-LAK) cells and study the synergistic anti-tumor effect of phenylacetate (PA) and A-LAK cells. Methods: A-LAK cells were obtained from pe...
关键词:Adherent lymphokine-activated killer cells PHENYLACETATE hepatocellular carcinoma phenylalanine methyl ester 
Effects of cryopreservation and phenylacetate on biological characters of adherent LAK cells from patients with hepatocellular carcinoma被引量:16
《World Journal of Gastroenterology》2002年第2期233-236,共4页Ning Zheng Sheng-Long Ye Rui-Xia Sun Yan Zhao Zhao-You Tang,Liver Cancer Institute and Zhongshan Hospital,Fudan University,Shanghai 200032,China 
the National 9th Five-Year Program of China,No.96-906-01-20
AIM: To improve the preparation of adherent lymphokine-activated killer (A-LAK) cells and to study the effects ofcryopreservation and phenylacetate (PA) on biologicalcharacters of A-LAK cells.METHODS: A-LAK cells were...
关键词:肝细胞癌 粘附淋巴因子活化杀伤细胞 冷冻保存 醋酸苯酯 
Synthesis, molecular structure and intramolecular aromatic-ring stacking interaction of a novel binuclear Cu(Ⅱ) complex with 1, 10-phenanthroline and phenylacetate被引量:3
《Chinese Journal of Chemistry》2000年第4期638-642,共5页乐学义 周晓华 郁开北 计亮年 
Project supported by the National Natural Science Foundation of China (No. 29571033) and the Natural Science Foundation of Guangdong Province (No.974207).
The complex [Cu(phen)2(POAc)3]ClO·4H2O has been synthesized and investigated by elemental analysis, IR spec-troscopy and X-ray diffraction methods, where phen = 1,10-phenanthroline, POAc = phenylacetate group). The c...
关键词:PHENANTHROLINE phenykcetate copper(Ⅱ) complex stacking interaction crystal structure 
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