TRICYCLIC

作品数:44被引量:28H指数:3
导出分析报告
相关领域:理学天文地球更多>>
相关作者:宋孚庆任冬苓张文龙王汇彤梁泽芳更多>>
相关机构:中国石油天然气集团公司华南师范大学更多>>
相关期刊:《Acta Pharmacologica Sinica》《Science China Chemistry》《Journal of Mathematical Research with Applications》《World Journal of Gastroenterology》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划北京市自然科学基金河北省自然科学基金更多>>
-

检索结果分析

结果分析中...
条 记 录,以下是1-10
视图:
排序:
Cobalamin-dependent radical S-adenosyl-L-methionine protein functions with a partner to successively methylate tricyclic indole alkaloid for chuangxinmycin maturation and derivatization
《Science China Chemistry》2025年第1期308-316,共9页Sili Wang Jiancheng Huang Yanan Du Wei Huang Yufeng Xue Xiaokun Xu Guannan Zhong Yuanyuan Shi Bin Hong Xiaoying Bian Wen Liu 
supported in part by the National Key Research and Development Program of China(2022YFC2303100);the National Natural Science Foundation of China(32030002,22193070);the Shanghai Post-Doctoral Excellence Program(2022718)。
Cobalamin(Cbl)-dependent radical S-adenosyl-L-methionine(SAM)proteins constitute the largest collection of the radical SAM superfamily that has hundreds of thousands of individual members.Many of these proteins are in...
关键词:cbl-dependent radical SAM protein biosynthesis chuangxinmycin stereoselective methylation 
Catalytic C-H activation-initiated transdiannulation:An oxygen transfer route to ring-fluorinated tricyclic γ-lactones
《Chinese Chemical Letters》2024年第9期145-149,共5页Qiuyun Li Yannan Zhu Yining Wang Gang Qi Wen-Juan Hao Kelu Yan Bo Jiang 
financial support from the schoollevel research projects of Yancheng Institute of Technology(No.xjr2020044);the National Natural Science Foundation of China(Nos.22101152,22271123 and 21971090)。
Catalytic C–H activation-initiated annulation reactions have emerged as a versatile strategy for the efficient construction of diverse ring structural units and complex cyclic molecules in synthetic chemistry.Herein,...
关键词:C-H bond activation ENAMINONES Transannulation Oxygen transfer Regioselectivity 
Electrochemical synthesis of 3-halogenated spiro [4,5]trienones based on dearomative spirocyclization strategy
《Green Synthesis and Catalysis》2023年第4期306-310,共5页Zhiwei Chen Wei Tang Shuhang Yang Luyao Yang 
We gratefully acknowledge the Provincial Planning Project of the Zhejiang Provincial Science and Technology Department(No.LGF19B060005)for financial support.
A novel and green route have been developed for the electrochemical synthesis of 3-halogenated spiro[4.5]trienones based on dearomative spirocyclization of alkynes with NaX(Br,I)as the halogen source.This transformati...
关键词:Electrochemistry Spiro-cyclization METAL-FREE Tricyclic frameworks Spiro[4 5]trienones 
Discovery and development of tricyclic matrinic derivatives as anti-diabetic candidates by AMPKαactivation
《Chinese Chemical Letters》2023年第1期289-294,共6页Yinghong Li Yuanhui Zhang Tianyu Niu Yudong Pang Yulong Shi Qingxuan Zeng Jingpu Zhang Jingyang Zhu Xiuli Zhong Yanxiang Wang Yan Wang Sheng Tang Weijia Kong Danqing Song Jiandong Jiang 
supported by CAMS Innovation Fund for Medical Sciences(No.2021-12M-1-030);the Natural Science Foundation of Beijing Municipality(No.7202131);Chinese Pharmaceutical Association-Yiling Pharmaceutical Innovation Fund for Biomedicine(No.GL-1-B04-20190397)。
We found compound 12N-p-trifluoromethylbenzenesulfonyl matrinane(1)was a potent anti-diabetic agent.Thirty-five tricyclic matrinic derivatives were synthesized and determined for their stimulatory effects on glucose c...
关键词:Tricyclic matrinic derivatives Glucose consumption Diabetes mellitus AMP-activated protein kinase(AMPK) 
Asymmetric synthesis of tricyclic 6,5,5-fusedpolycycles by the desymmetric Pauson–Khandreaction
《Organic Chemistry Frontiers》2022年第6期1680-1685,共6页Qi Teng Dong Chen Chen-Ho Tung Zhenghu Xu 
support from the Natural Science Foundation of China and Shandong Province(No.21971149,92156007,ZR2019ZD45,and ZR2020KB005);the Fundamental Research Funds of Shandong University.
A new rhodium(I)–BINAP-catalyzed enantioselective desymmetric Pauson–Khand (PK) reaction of prochiral 1,6-enynes with CO has been developed. Diverse tricyclic 6,5,5-fused bowl type polycycles withthree continuous ch...
关键词:FUSED symmetric CHIRAL 
A novel tricyclic BTK inhibitor suppresses B cell responses and osteoclastic bone erosion in rheumatoid arthritis被引量:1
《Acta Pharmacologica Sinica》2021年第10期1653-1664,共12页Yu-ting Liu Hui-hua Ding Ze-min Lin Que Wang Li Chen Shuang-shuang Liu Xiao-qian Yang Feng-hua Zhu Yue-teng Huang Shi-qi Cao Fang-ming Yang Zi-lan Song Jian Ding Mei-yu Geng Hua Xie Ao Zhang Shi-jun He Jian-ping Zuo 
This work was supported by the Personalized Medicines-Molecular Signature-based"Drug Discovery and Development,"Strategic Priority Research Program of the Chinese Academy of Sciences(grant No.XDA12020369);the National Natural Science Foundation of China(NSFC)(grant No.81903882);the National Science and Technology Major Project"New Drug Creation and Manufacturing Program",China(grant No.2018ZX09711002-014-001).
Rheumatoid arthritis(RA)is characterized by joint leukocyte infiltration,synovial inflammation and bone damage result from osteoclastogenesis.Bruton’s tyrosine kinase(BTK)is a key regulator of B cell receptor(BCR)and...
关键词:rheumatoid arthritis BTK inhibitors SOMCL-17-016 B cells MACROPHAGES RANKL OSTEOCLASTOGENESIS 
Geochemical significance of tricyclic and tetracyclic terpanes in source rock extracts from the Offshore Niger Delta Basin,Nigeria被引量:2
《Acta Geochimica》2021年第2期184-198,共15页Abiodun B.Ogbesejana Oluwasesan M.Bello Tijjani Ali Uduma A.Uduma Kamaluddeen S.Kabo Oluwadurotimi O.Akintade 
Tricyclic and tetracyclic terpanes are important constituents of crude oil and source rock extracts.However,they have not been reported in the Offshore Niger Delta Basin,Nigeria.Thus,the present study investigated the...
关键词:Tricyclic terpanes Tetracyclic terpanes Source rocks Niger delta Gas chromatography-mass spectrometry(GC-MS) 
Facile biphasic catalytic process for conversion of monoterpenoids to tricyclic hydrocarbon biofuels被引量:1
《Journal of Energy Chemistry》2020年第10期42-50,共9页Shaoqu Xie Trong HHuynh Peiyong Qin Tianwei Tan Hongfei Lin 
Terpenoids have drawn much attention to scientists in synthesizing high-performance bio-jet fuels due to their ring structures,which feature potential high densities.Here,a facile biphasic catalytic process has been d...
关键词:CINEOLE High-density biofuels Biphasic catalytic process Diels-Alder reaction DEHYDRATION 
Asymmetric synthesis of ABC tricyclic systems in Daphniphyllum alkaloid
《Chinese Chemical Letters》2020年第3期685-688,共4页Huijing Wang Qiuyan Dong Qinxia Xie Pei Tang 
supported by the National Natural Science Foundation of China(No.21502011);the Fundamental Research Funds for the Central Universities;the Chongqing Science&Technology Commission Project(No.cstc2016jcyjA0168)。
Efficient synthetic routs for the direct and rapid construction of[5-6-6]ABC tricyclic systems of daphmanidin A-type and calyciphylline A-type alkaloids have been successfully developed.For the daphmanidin A-type,the ...
关键词:Daphniphyllum ALKALOID Calyciohylline N 21-Deoxymacropodumine D ABC TRICYCLIC framework INTRAMOLECULAR ALDOL reaction PD-CATALYZED INTRAMOLECULAR oxidative alkylation 
The Inertia Indexes of One Special Kind of Tricyclic Graphs
《Applied Mathematics》2019年第1期11-18,共8页Haicheng Ma Chengling Xie 
Let G be a graph and A=(aij)n×n be the adjacency matrix of G, the eigenvalues of A are said to be the eigenvalues of the graph G, and to form the spectrum of this graph. The numbers of positive, negative and zero eig...
关键词:TRICYCLIC GRAPHS Positive INERTIA INDEX Negative INERTIA INDEX NULLITY 
检索报告 对象比较 聚类工具 使用帮助 返回顶部