financial supported by Innovation Program of Shanghai Municipal Education Commission(No.201701070002E00037);supported by National Key Research Program of China(No.2017YFD0200505);the Fundamental Research Funds for the Central Universities。
Deuteriodifluoromethyl(CF_(2)D)is a challenging and important functional group due to difficult deuterium incorporation and lack of effective precursor reagents.Herein,we report a bench-stable reagent,deuteriodifluoro...
the Ministry of Science and Technology of China(No.2016YFE0132600);Henan Center for Outstanding Overseas Scientists(No.GZS2020001)。
Cp^*Co(Ⅲ)-catalyzed direct C—H amidation of azines has been developed.This co nversion could proceed smoothly in the absence of external oxidants,acids or bases,with excellent regioselectivity and broad functional g...
New functionalized fused heterocycles, such as, 1,3,6,9,11-pentasubstituted-pyrido[3,2-f:6,5-f']bis([1,2,4]triazolo[4,3-a]-pyrimidin-5(1H)-ones (6) and 1,3-disubstituted-7-[(E)-2-(thiophen-2-yl)ethenyl]-1,4,9,9a-tetra...
A simple and efficient synthetic protocol has been developed using a one-pot, three-component reaction involving 2-amino phenols, dialkyl acetylene dicarboxylates and nitrostyrene derivatives. Utilizing this protocol,...
Unsymmetrical hybrid chiral phosphine-aminophosphine ligand derived from 1,2,3,4-tetrahydro-l-naphthyl- amine has been found to be highly efficient in the Ir-catalyzed asymmetric hydrogenation of various 3-aryl-2H-1,4...
The synthesis of a new series of six-membered N,N′-diarylsubstituted methylene-bis-dihydro-2H-1,3-benzoxazines (5a-e) was achieved in excellent yields by Mannich-type condensation of N,N′-diarylsubstituted methyle...
1 Results Electropolymerized azines are considered an important group of mediators for NAD+/ NADH-based biocatalytic applications[1].Characterizing these electroactive polymers in situ on electrode surface is vital to...
Project supported by the National Natural Science Foundation of China (No. 20172065).
The reaction of 3-(1-hydropolyfluoroalkenyl)-1-oxo-2,4,1-benzoxazines 1 with some dinucleophiles was investigated. 7-Fluoroalkyl-2,3-dihydro- 1,4-diazepine[ 1,2-d]quinazolin- 11-ones 2, 2-fluoroalkylisoxazolo[3,2-b]...
A new convenient and environmentally benign procedure for synthesis of azines from hydrazme sulfate with several aromatic aldehydes coupled with grinding is studied. This reaction is carried out under solvent-free con...