IMIPRAMINE

作品数:16被引量:62H指数:4
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相关领域:医药卫生更多>>
相关作者:杨进刘千勇王晓良瞿介明更多>>
相关机构:复旦大学中国医学科学院北京协和医学院安徽医科大学徐州医科大学更多>>
相关期刊:《World Journal of Neuroscience》《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《World Journal of Pediatrics》更多>>
相关基金:国家自然科学基金更多>>
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Role of serendipity in the discovery of classical antidepressant drugs:Applying operational criteria and patterns of discovery
《World Journal of Psychiatry》2022年第4期588-602,共15页Francisco López-Muñoz Pilar D’Ocón Alejandro Romero JoséA Guerra CecilioÁlamo 
The role played by serendipity in the origin of modern psychopharmacology has proven to be controversial in scientific literature.In its original meaning(Walpole),serendipity refers to discoveries made through a combi...
关键词:Serendipity Antidepressants IMIPRAMINE Iproniazid PSYCHOPHARMACOLOGY History of neurosciences 
Imipramine-precipitated status epilepticus
《World Journal of Pediatrics》2021年第2期218-219,共2页Ahmed Naguy 
Frontal lobe epilepsy has a complex and atypical semiology that may masquerade as psychiatric or parasomnias[1].An electroencephalography(EEG)and sleep lab workup should be an integral part of clinical assessment of t...
关键词:EPILEPSY CLINICAL epileptic 
Acid sphingomyelinase downregulation alleviates vascular endothelial leptin resistance in rats被引量:1
《Acta Pharmacologica Sinica》2020年第5期650-660,共11页Bei-bo Cai Yi-ni Lu Ming Xu 
the National Natural Science Foundation of China(Nos.81570413,81773732,and 81973509).
Leptin resistance in endothelial cells leads to vascular endothelial dysfunction,which is the beginning and crucial link of atherosclerosis.However,the mechanism of leptin resistance remains obscure.Acid sphingomyelin...
关键词:leptin resistance rat aortic endothelial cells acid sphingomyelinase CERAMIDE Ob-Rb SOCS3 STAT3 ERK1/2 Akt AMITRIPTYLINE IMIPRAMINE atherosclerosis 
Modulation of Anxiolytic-Like and Antidepressant-Like Effects of Melatonin by Imipramine in Wistar Rats: Possible Interaction with Central Monoaminergic Systems
《Neuroscience & Medicine》2019年第2期118-133,共16页Sihame Ouakki Oussama Zghari Aboubaker El Hessni Abdelhalem Mesfioui Ali Ouichou 
Our current study aims to explore the interaction of melatonin (MEL) with the monoaminergic system on the pathophysiology of affective disorders in Wistar rats. We mention here that, the role of monoaminergic transmis...
关键词:MELATONIN IMIPRAMINE Depression Anxiety Open Field TEST Elevated Plus MAZE Forced SWIMMING TEST 
Effects of voluntary imipramine intake via food and water in paradigms of anxiety and depression in naive mice
《Translational Neuroscience and Clinics》2016年第3期172-182,149,共12页Joao Pedro Costa-Nunes Anastassia Bakhmet Margarida Araújo-Correia Andreia Barbosa Valenca Tatyana Strekalova Harry W.M.Steinbusch 
the the Fundacao para a Ciência e Tecnologia(FCT)and Internationale Stichting Alzheimer Onderzoek(ISAO);the Netherlands,grant N 09501 and RFBR 11-04-01411 to TS
Objective: We sought to investigate the efficacy of oral dosing in mice with imipramine(7mg/kg/day) via water or in food pellets, and to compare its effects in the paradigms of learned helplessness, locomotion, hedoni...
关键词:pre-clinical models depression anxiety oral dosing animal welfare 
Salvianolic acid B ameliorates depressive-like behaviors in chronic mild stress-treated mice: involvement of the neuroinflammatory pathway被引量:23
《Acta Pharmacologica Sinica》2016年第9期1141-1153,共13页Jin-qiang ZHANG Xiao-hui WU Yi FENG Xiao-fang XIE Yong-hua FAN Shuo YAN Qiu-ying ZHAO Cheng PENG Zi-li YOU 
Aim: Major depressive disorder (MDD) is a debilitating mental disorder associated with dysfunction of the neurotransmitter- neuroendocrine system and neuroinflammatory responses. Salvianolic acid B (SalB) has sho...
关键词:major depressive disorder chronic mild stress ANTIDEPRESSANT salvianolic acid B IMIPRAMINE CYTOKINES apoptosis microglia activation 
Management of nocturnal enuresis-myths and facts被引量:18
《World Journal of Nephrology》2016年第4期328-338,共11页Rajiv Sinha Sumantra Raut 
Nocturnal enuresis often causes considerable distress or functional impairment to patient and their parents necessitating a multidisciplinary approach from paediatrician, paediatric nephrologist, urologists and psychi...
关键词:Nocturnal enuresis Monosymptomatic Conditioning alarm DESMOPRESSIN IMIPRAMINE 
Imipramine protects retinal ganglion cells from oxidative stress through the tyrosine kinase receptor B signaling pathway被引量:5
《Neural Regeneration Research》2016年第3期476-479,共4页Ming-lei Han Guo-hua Liu Jin Guo Shu-juan Yu Jing Huang 
Retinal ganglion cell(RGC) degeneration is irreversible in glaucoma and tyrosine kinase receptor B(Trk B)-associated signaling pathways have been implicated in the process.In this study,we attempted to examine whe...
关键词:nerve regeneration retinal ganglion cell imipramine oxidative stress apoptosis tyrosine kinase receptor B neural regeneration 
Failure of memantine to “reverse” quinpirole-induced hypomotility
《World Journal of Psychiatry》2016年第2期215-220,共6页Francesca Demontis Gino Serra 
Supported by Fondazione Banco di Sardegna,Italy(Grant no 2013 U718/AI.642.MGB)
AIM: To evaluate antidepressant-like effect of memantine in a rat model.METHODS: Male Wistar rats were treated intraperitoneally with either vehicle, memantine(10 mg/kg) or imipramine(20 mg/kg), for 3 wk. Twenty-four ...
关键词:MEMANTINE Bipolar disorder Depression MOOD STABILIZER IMIPRAMINE D2 SENSITIZATION 
The Effect of Neurofeedback Therapy in Primary Enuretic Children
《World Journal of Neuroscience》2015年第2期87-90,共4页Mahmood Reza Khazaei Nasrin Aminifard Peyman Hashemian 
Introduction:?Enuresis is one of the most common psychiatric disorders in children. Classical?treatments for primary enuretic children are conditioning (Bell and Pad method, and drug therapy). Neurofeedback is a kind ...
关键词:IMIPRAMINE NEUROFEEDBACK ENURESIS 
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