OSTEOINTEGRATION

作品数：24被引量：60H指数：5
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相关机构：南方医科大学更多>>
相关期刊：《Journal of Wuhan University of Technology(Materials Science)》《Chinese Journal of Traumatology》《Regenerative Biomaterials》《Science China Materials》更多>>
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Fabrication, bacteriostasis and osteointegration properties researches of the additively-manufactured porous tantalum scaffolds loading vancomycin被引量：2
《Bioactive Materials》2023年第6期450-462,共13页Hu Qian Ting Lei Long Hua Yu Zhang Dongyu Wang Jiangyu Nan Wenbin Liu Yan Sun Yihe Hu Pengfei Lei 
supported by the Key research and development program of Hunan Province(Grant No.2020SK2008 and 2021GK2012);the Major science and technology projects of Changsha City(Grant No.kh2003016);Clinical research fund of National Clinical Research Center for Geriatric Disorders(Xiangya Hospital,Grant No.2020LNJJ15);The Natural Science Foundation Exploration Project of Zhejiang Province,China(Grant No.Y23H060040);the Natural Science Foundation of Hunan Province,China(Grant No.2022JJ30934).
Infected bone defects(IBDs)remains a challenging problem for orthopedists.Clinically,routine management for IBDs has two stages:debridement and systematic antibiotics administration to control infection,and secondary ...
关键词：Infected bone defects Porous tantalum PLGA microspheres VANCOMYCIN 
Biomimetic AgNPs@antimicrobial peptide/silk fibroin coating for infection-trigger antibacterial capability and enhanced osseointegration被引量：10
《Bioactive Materials》2023年第2期64-80,共17页Wenhao Zhou Tian Bai Lan Wang Yan Cheng Dandan Xia Sen Yu Yufeng Zheng 
supported by the National Natural Science Foundation of China(Grant numbers 32071327,32101087);Shaanxi Science and Technology Association(2022JQ-312).
Endowing implant surfaces with combined antibacterial and osteogenic properties by drug-loaded coatings has made great strides,but how to achieve the combined excellence of infection-triggered bactericidal and in vivo...
关键词：Antimicrobial peptides AGNPS ANTIBACTERIAL OSTEOINTEGRATION Titanium 
Porous tantalum structure integrated on Ti6Al4V base by Laser Powder Bed Fusion for enhanced bony-ingrowth implants:In vitro and in vivo validation被引量：5
《Bioactive Materials》2022年第1期3-13,共11页Pengfei Lei Hu Qian Taomei Zhang Ting Lei Yihe Hu Chao Chen Kechao Zhou 
This study was supported by the Natural Science Foundation of Hunan Province,China(Grant No.2019JJ40499);the Scientific Research Project of Health and Family Planning Commission of Hunan Province,China(Grant No.B2019188);the Science and technology Innovation Leading Project for High-tech Industry of Hunan Province(Grant No.2020SK2008);the Major science and technology projects of Changsha City(Grant No.42193);National key research and development project(2018YFB1105504);Natural Science Foundation of China(Grant No.82002277 and 81672656).
Despite the widespread application of Ti6Al4V and tantalum(Ta)in orthopedics,bioinertia and high cost limit their further applicability,respectively,and tremendous efforts have been made on the Ti6Al4V-Ta alloy and Ta...
关键词：Tantalum TI6AL4V Laser powder bed fusion Orthopedic scaffolds OSTEOINTEGRATION 
Antibiotic-loaded amphora-shaped pores on a titanium implant surface enhance osteointegration and prevent infections被引量：4
《Bioactive Materials》2021年第8期2331-2345,共15页Viviane Ständert Kai Borcherding Nicole Bormann Gerhard Schmidmaier Ingo Grunwald Britt Wildemann 
This work was funded by the Federal Ministry of Education and Research,Germany[grant numbers 03VP03681,03VP03682].
Artificial prostheses for joint replacement are indispensable in orthopedic surgery.Unfortunately,the implanted surface is attractive to not only host cells but also bacteria.To enable better osteointegration,a mechan...
关键词：Titanium implants Laser structuring Amphora-shaped pores Gentamicin loading Antimicrobial silver particles 
Gaseous sulfur trioxide induced controllable sulfonation promoting biomineralization and osseointegration of polyetheretherketone implants被引量：7
《Bioactive Materials》2020年第4期1004-1017,共14页Teng Wan Zixue Jiao Min Guo Zongliang Wang Yizao Wan Kaili Lin Qinyi Liu Peibiao Zhang 
financially supported by the National Natural Science Foundation of China(Projects.51673186 , 81672263);the Special Fund for Industrialization of Science and Technology Cooperation between Jilin Province and Chinese Academy of Sciences(2017SYHZ0021).
Fabricating a desired porous structure on the surface of biomedical polyetheretherketone(PEEK)implants for enhancing biological functions is crucial and difficult due to its inherent chemical inertness.In this study,a...
关键词：POLYETHERETHERKETONE SULFONATION Micro-topology Mechanical strength OSTEOINTEGRATION 
Biofunctionalization of metallic implants by calcium phosphate coatings被引量：14
《Bioactive Materials》2019年第1期196-206,共11页Yingchao Su Irsalan Cockerill Yufeng Zheng Liping Tang Yi-Xian Qin Donghui Zhu 
supported by National Institutes of Health[Grant number R01HL140562]。
Metallic materials have been extensively applied in clinical practice due to their unique mechanical properties and durability.Recent years have witnessed broad interests and advances on surface functionalization of m...
关键词：Calcium phosphates Metallic implant materials Surface biofunctionalization OSTEOINTEGRATION BIODEGRADATION 
An in vivo study on the effect of coating stability on osteointegration performance of collagen/hyaluronic acid multilayer modified titanium implants被引量：2
《Bioactive Materials》2018年第1期97-101,共5页Haiyong Ao Jiajia Zong Yanjiao Nie Yizao Wan Xiebin Zheng 
This work is supported by the National Natural Science Foundation of China(Grant No.81501856).
Aseptic loosening of implant is one of the main causes of Ti-based implant failure.In our previous work,a novel stable collagen/hyaluronic acid(Col/HA)multilayer modified titanium coatings(TCs)was developed by layer-b...
关键词：Collagen I Hyaluronic acid LBL covalent immobilization STABILITY OSTEOINTEGRATION 
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