OSTEOINTEGRATION

作品数:24被引量:60H指数:5
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相关领域:医药卫生更多>>
相关机构:南方医科大学更多>>
相关期刊:《Journal of Wuhan University of Technology(Materials Science)》《Chinese Journal of Traumatology》《Regenerative Biomaterials》《Science China Materials》更多>>
相关基金:国家自然科学基金广东省自然科学基金中国博士后科学基金国家重点基础研究发展计划更多>>
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A design strategy for long-term stability of porous PEEK implants by regulation of porous structure and in vivo mechanical stimulation
《Bio-Design and Manufacturing》2025年第2期275-287,I0004,共14页Yingjie Liu Ling Wang Jie Zhang Shuguang Liu Jibao Zheng Jianfeng Kang Enchun Dong Changning Sun Ruhan A Chaozong Liu Chuncheng Yang Dichen Li 
supported by the National Key R&D Program of China(No.2023YFB4603500);the Program for Innovation Team of Shaanxi Province(No.2023-CX-TD-17);the Fundamental Research Funds for the Central Universities;the Shaanxi Province Qinchuangyuan“Scientist+Engineer”Team Construction Project(No.2022KXJ-106).
The bioinert nature of polyether ether ketone(PEEK)material limits the widespread clinical application of PEEK implants.Although the porous structure is considered to improve osseointegration of PEEK implants,it is ha...
关键词:Porous polyether ether ketone(PEEK)implant OSTEOINTEGRATION Interface biomechanics Maxillofacial implants Finite element analyses Fused filament fabrication(FFF)3D printing 
Fabrication, bacteriostasis and osteointegration properties researches of the additively-manufactured porous tantalum scaffolds loading vancomycin被引量:2
《Bioactive Materials》2023年第6期450-462,共13页Hu Qian Ting Lei Long Hua Yu Zhang Dongyu Wang Jiangyu Nan Wenbin Liu Yan Sun Yihe Hu Pengfei Lei 
supported by the Key research and development program of Hunan Province(Grant No.2020SK2008 and 2021GK2012);the Major science and technology projects of Changsha City(Grant No.kh2003016);Clinical research fund of National Clinical Research Center for Geriatric Disorders(Xiangya Hospital,Grant No.2020LNJJ15);The Natural Science Foundation Exploration Project of Zhejiang Province,China(Grant No.Y23H060040);the Natural Science Foundation of Hunan Province,China(Grant No.2022JJ30934).
Infected bone defects(IBDs)remains a challenging problem for orthopedists.Clinically,routine management for IBDs has two stages:debridement and systematic antibiotics administration to control infection,and secondary ...
关键词:Infected bone defects Porous tantalum PLGA microspheres VANCOMYCIN 
Biomimetic AgNPs@antimicrobial peptide/silk fibroin coating for infection-trigger antibacterial capability and enhanced osseointegration被引量:10
《Bioactive Materials》2023年第2期64-80,共17页Wenhao Zhou Tian Bai Lan Wang Yan Cheng Dandan Xia Sen Yu Yufeng Zheng 
supported by the National Natural Science Foundation of China(Grant numbers 32071327,32101087);Shaanxi Science and Technology Association(2022JQ-312).
Endowing implant surfaces with combined antibacterial and osteogenic properties by drug-loaded coatings has made great strides,but how to achieve the combined excellence of infection-triggered bactericidal and in vivo...
关键词:Antimicrobial peptides AGNPS ANTIBACTERIAL OSTEOINTEGRATION Titanium 
Immunomodulation and osteointegration of infected implants by ion-riched and hierarchical porous TiO_(2)matrix
《Nano Research》2023年第2期2905-2914,共10页Yang Xue Lan Zhang Fuwei Liu Liang Kong Yong Han 
supported by the National Natural Science Foundation of China(Nos.51771142 and 51971171);Natural Science Foundation of Shaanxi Province(No.2021JC-07).
Infection is a main cause of implant failure.The microenvironment cell experiencing after antimicrobial therapy of infected implants is very crucial for immunomodulation and subsequent osteointegration.Based on the su...
关键词:PHOTOTHERMAL ANTIBACTERIAL IMMUNOMODULATION OSTEOINTEGRATION 
CaP-coated Zn-Mn-Li alloys regulate osseointegration via influencing macrophage polarization in the osteogenic environment被引量:2
《Regenerative Biomaterials》2023年第1期1096-1110,共15页Huifen Qiang Caiyao Hou Yujue Zhang Xin Luo Jun Li Chunxiu Meng Kun Liu Zhaoyong Lv Ximeng Chen Fengzhen Liu 
supported by the Science Foundation of Shandong Province of China[Grant No.ZR2021MH026,ZR2022MH075];Medicine and Health Science Technology Development plan of Shandong Province of China[Grant No.202108020440,2020Q127];Liaocheng Key Research and Development Plan of Shandong Province of China[Grant No.2022YDSF16,2022YDSF21];Liaocheng People’s Hospital Youth Fund Project[Grant No.LYQN201914].
Immune response is an important factor in determining the fate of bone replacement materials,in which macrophages play an important role.It is a new idea to design biomaterials with immunomodulatory function to reduce...
关键词:Zn-Mn-Li alloys CaP coatings macrophages polarization OSTEOINTEGRATION inflammation 
Functionalized TiCu/TiCuN coating promotes osteoporotic fracture healing by upregulating the Wnt/β-catenin pathway
《Regenerative Biomaterials》2023年第1期126-139,共14页Jia Tan Ling Ren Kai Xie Lei Wang Wenbo Jiang Yu Guo Yongqiang Hao 
supported by the National Natural Science Foundation of China[81972058 and 81902194];the Science and Technology Commission of Shanghai Municipality[22YF1422900 and 21002411200];the Shanghai Municipal Key Clinical Specialty,China[shslczdzk06701];Huangpu District Industrial Support Fund[XK2020009];the National Facility for Translational Medicine(Shanghai),China[TMSZ-2020-207];the Shanghai Engineering Research Center of Orthopedic Innovative Instruments and Personalized Medicine Instruments and Personalized Medicine[19DZ2250200].
Osteoporosis results in decreased bone mass and insufficient osteogenic function.Existing titanium alloy implants have insufficient osteoinductivity and delayed/incomplete fracture union can occur when used to treat o...
关键词:nitride-titanium-copper orthopaedic implant OSTEOGENESIS OSTEOINTEGRATION osteoporotic fractures 
Ultrafine-grained Nb-Cu immiscible alloy implants for hard tissue repair:Fabrication,characterization,and in vitro and in vivo evaluation被引量:1
《Journal of Materials Science & Technology》2022年第32期214-224,共11页Chuanxin Zhong Dingshan Liang Tian Wan Shan He Lu Yang Ju Fang Ge Zhang Fuzeng Ren 
the National Natural Science Foundation of China(No.52122102);the Natural Science Foundation of Guangdong(No.2019A1515011755);the Shenzhen Fundamental Research Project(No.JCYJ20190809153205492)。
The biocompatible metallic implants with strong osteointegration often lack the ability of anti-infection.The biocompatible niobium(Nb)containing the antibacterial copper(Cu),the obtained Nb-Cu alloy,could be a potent...
关键词:Nb-Cu immiscible alloy Antibacterial OSTEOGENESIS Bone screws OSTEOINTEGRATION 
Tempering force with mercy:An innovative peri-implant ligament with combined osteointegration and energy-dissipation
《Nano Research》2022年第5期4466-4467,共2页Xun Wang 
Designing and developing metal implants as permanent hard tissue substitutes to achieve both osteointegration and energy-dissipation has been a long-standing theme of fundamental and clinical research[1].However,these...
关键词:OVERLOAD dissipation energy 
Modification of polyetheretherketone(PEEK)physical features to improve osteointegration被引量:6
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2022年第3期189-203,共15页Dan YU Xiaoyue LEI Huiyong ZHU 
This work was supported by the National Natural Science Foundation of China(No.31570989);the Young Talents Project of Zhejiang Provincial Health Department(No.2019RC151);the Zhejiang Provincial Welfare Technology Research Project(No.LGF20H140007),China.
Polyetheretherketone(PEEK)has been widely applied in orthopedics because of its excellent mechanical properties,radiolucency,and biocompatibility.However,the bioinertness and poor osteointegration of PEEK have greatly...
关键词:Polyetheretherketone(PEEK) Surface topography Architecture STIFFNESS Bone integration 
Promoting osteointegration effect of Cu-alloyed titanium in ovariectomized rats
《Regenerative Biomaterials》2022年第1期143-155,共13页Xiyue Zhang Hui Liu Ling Li Cuishan Huang Xiangbo Meng Junzuo Liu Xueling Bai Ling Ren Xinluan Wang Ke Yang Ling Qin 
supported by the Key Program for Foreign Cooperation of Chinese Academy of Sciences[grant number 174321KYSB20180006];the National Natural Science Foundation of China[grant number 51631009];the International Cooperation Program of Shenzhen Science and Technology Innovation Commission(grant number GJHZ20190821160803823).
Osteoporosis is a common skeletal disease making patients be prone to the osteoporotic fracture.However,the clinical implants made of titanium and its alloys with a poor osseointegration need a long time for healing a...
关键词:copper-alloyed titanium alloy OSTEOPOROSIS implant OSSEOINTEGRATION VASCULARIZATION 
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