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作品数:342被引量:639H指数:13
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相关领域:医药卫生更多>>
相关作者:梁倩倩王拥军侯炜崔学军周泉更多>>
相关机构:上海中医药大学华中科技大学军事医学科学院中山医科大学附属第一医院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>
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Prolonged consumption of dietary advanced lipoxidation end products contributes to renal impairment in mice through dysregulated intestinal homeostasis
《Food Science and Human Wellness》2025年第4期1291-1304,共14页Yaya Wang Lu Dong Yaozhong Hu Tianchang Zhang Ruican Wang Linqing Nie Junping Wang Yan Zhang Shuo Wang 
supported by grants from the National Natural Science Foundation of China(32030083)。
Heat processing of food has been well validated as the trigger to generate heat-processing side product of advanced lipoxidation end products(ALEs),which potentially engenders the threat on systemic health or progress...
关键词:Dietary advanced lipoxidation end products Renal insufficiency Gut microbiota Fecal metabolites Intestinal barrier AMPK/SIRT1 signaling pathway 
Prolonged intermittent theta burst stimulation restores the balance between A_(2A)R-and A_(1)R-mediated adenosine signaling in the 6-hydroxidopamine model of Parkinson's disease
《Neural Regeneration Research》2025年第7期2053-2067,共15页Milica Zeljkovic Jovanovic Jelena Stanojevic Ivana Stevanovic Milica Ninkovic Tihomir V.Ilic Nadezda Nedeljkovic Milorad Dragic 
supported by a grant from Ministry of Science,Technological Development and Innovation,Serbia,No.451-03-68/2022-14/200178(to NN);University of Defence,No.MFVMA/02/22-24(to MN)。
An imbalance in adenosine-mediated signaling,particularly the increased A_(2A)R-mediated signaling,plays a role in the pathogenesis of Parkinson's disease.Existing therapeutic approaches fail to alter disease progress...
关键词:A_(1)R A_(2A)R adenosine receptors ADENOSINE ecto-5′-nucleotidase intermittent theta burst stimulation non-invasive brain stimulation Parkinson's disease purinergic signalling 
Effect and Safety of Fuzheng Huazhuo Decoction against Prolonged SARS-CoV-2 Clearance:A Retrospective Cohort Study
《Chinese Journal of Integrative Medicine》2025年第5期387-393,共7页ZHANG Wen WU Hong-ze XU Xiang-ru PU Yu-ting CHEN Cai-yu DENG Rou CAO Min SUN Ding YI Hui ZHOU Shuang FANG Bang-jiang 
Supported by the State Administration of Traditional Chinese Medicine;Traditional Chinese Medicine for the Prevention and Treatment of Novel Coronavirus Pneumonia Emergency and Special Project (No. 2022ZYLCYJ05-4);Shanghai University of Traditional Chinese Medicine,Traditional Chinese Medicine on Prevention and Treatment of Novel Coronavirus Pneumonia Emergency and Special Project (Nos. 2022YJ-03 and 2022YJ-06)。
Objective To evaluate the effect and safety of Chinese medicine(CM)Fuzheng Huazhuo Decoction(FHD)in treating patients with coronavirus disease 2019(COVID-19)who persistently tested positive for severe acute respirator...
关键词:Chinese medicine Fuzheng Huazhuo Decoction coronavirus disease 2019 prolonged viral clearance 
Precocious maturation and semi-multivoltine lifecycle in asubtropical grass lizard, Takydromus toyamai
《Current Zoology》2025年第2期184-195,共12页Hitomi Asato Mamoru Todab 
supported fnancially by the Nanseishoto Project of WWFJ,Pro Natura Foundation Japan’s 31st Pro Natura Fund;the Project for Biodiversity Conservation Promotion of the Japan Ministry of the Environment.
There are many short-lived animals,but those displaying a lifecycle with more than one generation per year(multivoltine lifecycle)are rare amongterrestrial vertebrates.The multivoltine lifecycle requires rapid growth ...
关键词:CAPTURE-MARK-RECAPTURE fast growth LACERTIDAE prolonged breeding season short-lived subtropical climate 
Expert consensus on issues related to abnormal uterine bleeding inadolescence
《Gynecology and Obstetrics Clinical Medicine》2025年第1期13-23,共11页Xin Yang Huina Su Huiying Zhang Shan Deng 
INTRODUCTION Abnormal uterine bleeding(AUB)is the most common reason adolescent females visit gynaecologists.From the onset of menarche,symptoms such as heavy menstrual bleeding(HMB)and/or prolonged menstruation can a...
关键词:abnormal uterine bleeding heavy menstrual bleeding hmb heavy menstrual bleeding abnormal uterine bleeding aub ADOLESCENCE physical health prolonged menstruation mental health 
Outcomes of patients with acute ST-segment elevation myocardial infarction treated by a prolonged“Deferred”percutaneous coronary intervention strategy
《World Journal of Cardiology》2025年第2期52-60,共9页Akshyaya Pradhan Shivam Uppal Pravesh Vishwakarma Abhishek Singh Monika Bhandari Ayush Shukla Akhil Sharma Gaurav Chaudhary Sharad Chandra Rishi Sethi Sudhanshu Kumar Dwivedi 
BACKGROUND Primary percutaneous coronary intervention(PCI)is the preferred treatment for ST-segment elevation myocardial infarction(STEMI).However,in patients with high thrombus burden,immediate stenting during PCI ca...
关键词:Myocardial infarction Percutaneous coronary intervention ST elevation myocardial infarction STENTS Coronary angiography 
Maize Prolonged Prophase 1 is essential for meiotic progression in pollen mother cells
《The Crop Journal》2025年第1期170-180,共11页Lingling Pan Yunfei Li Xueli An Zhiqi Xin Zhaobin Dong Weiwei Jin Wei Huang 
supported by National Key Research and Development Program of China(2022YFF1003501);Biological BreedingMajor Projects(2023ZD04076);Funds from State Key Laboratory of Maize Bio-breeding(SKLMB2404,SKLMB2440);Anhui Natural Science Foundation(2308085QC92).
Meiosis,a critical process for sexual reproduction,requires precise regulation to ensure the correct progression of meiotic stages.In yeast and animals,errors in meiotic recombination and homologous chromosomes synaps...
关键词:MAIZE Male sterile MEIOSIS PHD-finger protein 
Enhanced radiotheranostic targeting of integrinα5β1 with PEGylation-enabled peptide multidisplay platform(PEGibody):A strategy for prolonged tumor retention with fast blood clearance
《Acta Pharmaceutica Sinica B》2025年第2期692-706,共15页Siqi Zhang Xiaohui Ma Jiang Wu Jieting Shen Yuntao Shi Xingkai Wang Lin Xie Xiaona Sun Yuxuan Wu Hao Tian Xin Gao Xueyao Chen Hongyi Huang Lu Chen Xuekai Song Qichen Hu Hailong Zhang Feng Wang Zhao-Hui Jin Ming-Rong Zhang Rui Wang Kuan Hu 
supported by the National Natural Science Foundation of China(No.82372002);the Nonprofit Central Research Institute Fund of the Chinese Academy of Medical Sciences(No.2022-RC350-04,China);the CAMS Innovation Fund for Medical Sciences(Nos.2021-I2M-1-026(2023),2022-I2M-2-002-2,and 2021-I2M-3-001(2023),China);the National Key Research and Development Program of China(No.2022YFE0111700);the Beijing Nova Program to Kuan Hu(No.0104002,China);supported by the Beijing Natural Science Foundation(No.L234044,China);the Fundamental Research Funds for the Central Universities(Nos.3332023044 and 3332023151,China);the CIRP Open Fund of Radiation Protection Laboratories(No.ZHYLYB2021005,China);the China National Nuclear Corporation Young Talent Program.
Peptide-based radiopharmaceuticals targeting integrinα5β1 show promise for precise tumor diagnosis and treatment.However,current peptide-based radioligands that targetα5β1 demonstrate inadequate in vivo performanc...
关键词:Integrinα5β1 PEPTIDE PET imaging Targeted radionuclide therapy PEGYLATION TUMOR Multidisplay PEGibody 
NiSe nanoparticles anchored on hollow carbon nanofibers with enhanced rate capability and prolonged cycling durability for sodium-ion batteries
《Rare Metals》2025年第1期185-194,共10页Li-Jun Xu Xue-Jie Wang Guo-Yu Tang Bi-Cheng Zhu Jia-Guo Yu Liu-Yang Zhang Tao Liu 
supported by the National Natural Science Foundation of China(No.22075217);the Key Research and Development Program of Hubei Province(No.2023BAB113);the Natural Science Foundation of Hubei Province of China(Nos.2022CFA001 and 2023CFA088).
Nickel selenides have been studied as potential anode materials for sodium-ion batteries due to their high theoretical capacity.However,the low electrical conductivity and the large volumetric variation during the cha...
关键词:Nickel selenide Hollow porous structure Sodium storage Anode material 
Teriparatide as a non-surgical salvage therapy for prolonged humerus fracture nonunion:A case report and literature review
《World Journal of Orthopedics》2025年第1期79-85,共7页Shao-Han Guo Chong Li Yi-Jun Gao Zhen Zhang Ke Lu 
Supported by National Natural Science Foundation of China,No.82172441;Suzhou City Major Disease Multicenter Clinical Research Project,No.DZXYJ202312;Special Funding for Jiangsu Province Science and Technology Plan(Key Research and Development Program for Social Development),No.BE2023737;Gusu Health Talent Plan Scientific Research Project,No.GSWS2022109;Postgraduate Research and Practice Innovation Program of Jiangsu Province,No.SJCX24_2446.
BACKGROUND Fracture nonunion represents a challenging complication during fracture repair,often necessitating surgical intervention.Teriparatide,a recombinant human parathyroid hormone,has demonstrated promise in enha...
关键词:TERIPARATIDE Humerus fracture nonunion Fracture healing Prolonged nonunion Osteoanabolic therapy Bone regeneration Case report 
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