National Key R&D Program of China(Grant no.2021YFA1500200);the National Natural Science Foundation of China(Nos.92256303,92056108 and 21871270)for financial support.
Chiral ruthenium-catalyzed enantioselective hydrogenation of tetrapyridine-type N-heteroarenes was firstly developed.The partial reduction of adjacent tetraheteroaromatic substrates proceeded smoothly in the presence ...
supported by the National Key R&D Program of China(Nos.2021YFE0104900,2020YFA0710200);the National Natural Science Foundation of China(No.22078103);Shanghai Natural Science Fund(No.18ZR1411100).
Main observation and conclusion Three diamines(1,8-diaminooctane/p-phenylenediamine/biphenylenediamine)with different alkyl groups were used to synthesize the functionalized graphene networks.Pd as the common metal ca...
A mild and efficient synthesis of spiroquinoxalinones via tandem condensation of chlorooxoindoline 1 with benzene-1,2-diamines 2 is described.And a plausible mechanism for the reaction is proposed.
We thank the National Natural Science Foundation of China(Grant No.21232008);National Basic Research Program of China(973 Program,2010CB-833300),Foundation for University Youth Key Teacher of Henan Province(2013GGJS-207)and the Chinese Academy of Sciences(CMS-PY-201303)for financial supports.
The first asymmetric hydrogenation of unfunctionalized 2-substituted and 2,3-disubstituted 5,6-dihydropyrazines catalyzed by chiral cationic Ru-diamine complex(R,R)-1a was developed,affording chiral piperazine derivat...
This work was supported by the National Natural Science Foundation of China(21390400,21025208 and 21202171);the Ministry of Science and Technology(MoST)(2011CB808600)and the Chinese Academy of Sciences.
A simple and directα-allylic alkylation of unmodified aldehydes with allylic alcohols catalyzed by primary amine/Brønsted acid has been developed.The N,N-dimethylethylenediamine/TfOH was identified as the optimal cat...
the National Natural Science Foundation of China(No.21272166);the Major Basic Research Project of the Natural Science Foundation of the Jiangsu Higher Education Institutions(No.13KJA150004);the Program for New Century Excellent Talents in University(No.NCET-12-0743).
Chiral molecules containing sulfonyl and 1,5-diol moieties are useful synthetic blocks for various asymmetric transformations.A protocol has been developed for the enantioselective synthesis of optically active bis(β...
the National Natural Foundation Research Grant,the Shandong Provincial Natural Science Foundation,the Program for New Century Excellent Talents in University,Independent Innovation Foundation of Shandong University,the Open Research Fund of State Key Laboratory of Natural and Biomimetic Drugs in Peking University
Novel purine-2,6-diamine derivatives were designed and synthesized as cyclin-dependent kinase (CDK) inhibi- tors. According to the preliminary biological evaluation, most of the compounds show good inhibitory activi...
This work was supported by the National Natural Science Foundation of China (No. 51103016), the Natural Science Foundation of Jiangsu Province (No. BK2011232 and BK2011241), the Grant-in-aid for Youth Innovation Fundation of Changzhou University (No. ZMFll020017 and ZMFl102037), and the Open- ing Project of State Key Laboratory for Modification of Chemical Fibers and Polymer Materials (No. LK1001).
A new unsymmetrical and noncoplanar diamine containing trifluoromethyl and trimethyl groups, 1,4-bis(4- amino-2-trifluoromethylphenoxy)-2,3,5-trimethylbenzene (2), was synthesized using 2,3,5-trimethylhydroquinone...
The syntheses of three mixed ligand chelate copper(II) complexes of the type [Cu(L)(acac)(H2O)]BPh4 where acac=acetyleacetonate; L=N,N-dimethyl,N′-benzylethane-1,2-diamine (L1), N,N-dimethyl, N′-2-methylbe...
Xanthan sulfuric acid is an efficient solid acid catalyst for the preparation of 2-aryl benzimidazoles in excellent yields. This method is applicable for the reaction of benzo[c][ 1,2,5]thiadiazole-4,5-diamine with al...