FALCIPARUM

作品数：89被引量：63H指数：4
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相关领域：医药卫生更多>>
相关作者：蒋琳郭敏刘晓雷清陈勇更多>>
相关机构：兰州生物制品研究所有限责任公司南通医学院中山医科大学南方医科大学更多>>
相关期刊：《World Journal of Translational Medicine》《Infectious Disease Modelling》《Advances in Biological Chemistry》《Open Journal of Synthesis Theory and Applications》更多>>
相关基金：泰国研究基金World Health Organization国家自然科学基金国家重点基础研究发展计划更多>>
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Insights into the pyrimidine biosynthetic pathway of human malaria parasite Plasmodium falciparum as chemotherapeutic target
《Asian Pacific Journal of Tropical Medicine》2016年第6期511-519,共9页Sudaratana R.Krungkrai Jerapan Krungkrai 
supported by the UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (CHEMAL, TDR/WHO);the National Science and Technology Development Agency of Thailand (NSTDA Career Development Award);the Thailand Research Fund (TRF Basic Research);the Office of Higher Education Commission (OHEC University Staff Development Consortium);Graduate School and Faculty of Medicine, Chulalongkorn University, Thailand
Malaria is a major cause of morbidity and mortality in humans. Artemisinins remain as the first-line treatment for Plasmodium falciparum(P. falciparum) malaria although drug resistance has already emerged and spread i...
关键词：MALARIA PLASMODIUM FALCIPARUM PYRIMIDINE biosynthetic pathway DRUG target DRUG development Chemotherapy 
Antimalarial qinghaosu/artemisinin: The therapy worthy of a Nobel Prize被引量：3
《Asian Pacific Journal of Tropical Biomedicine》2016年第5期371-375,共5页Jerapan Krungkrai Sudaratana Rochanakij Krungkrai 
supported by the UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (CHEMAL, TDR/WHO);the National Science and Technology Development Agency of Thailand (NSTDA Career Development Award);the Thailand Research Fund (TRF Basic Research);the Office of Higher Education Commission (OHEC University Staff Development Consortium), and Faculty of Medicine and Graduate School, Chulalongkorn University, Thailand
Malaria is a major cause of human morbidity and mortality in the tropical endemic countries worldwide. This is largely due to the emergence and spread of resistance to most antimalarial drugs currently available. Base...
关键词：MALARIA PLASMODIUM FALCIPARUM ARTEMISININ Qinghaosu Discovery Chemical structure Mechanism of action DRUG resistance 
Malaria parasite carbonic anhydrase:inhibition of aromatic/heterocyclic sulfonamides and its therapeutic potential被引量：10
《Asian Pacific Journal of Tropical Biomedicine》2011年第3期233-242,共10页Sudaratana R Krungkrai Jerapan Krungkrai 
Supported by a grant from UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases(No.900142,930143,960103,970074,990490);the National Science and Technology Development Agency of Thailand(Career Development Award ID no.01-38-007);the Thailand Research Fund(BasicResearch Grants ID No.BRG/13/2543.BRG4580020.BRG 4880006)
Plasmodium falciparum(P.falciparum) is responsible for the majority of life-threatening cases of human malaria,causing 1.5-2.7 million annual deaths.The global emergence of drug-resistant malaria parasites necessitate...
关键词：Malaria PLASMODIUM FALCIPARUM Carbonic ANHYDRASE Carbonic ANHYDRASE inhibitor Aromalic/heterocyclic SULFONAMIDES ANTIMALARIAL agents Drug target Parasitic disease 
Artemisinin resistance or tolerance in human malaria patients被引量：4
《Asian Pacific Journal of Tropical Medicine》2010年第9期748-753,共6页Jerapan Krungkrai Waranya Imprasittichai Sumintra Otjungreed Sawirasagee Pongsabut Sudaratana R Krungkrai 
supported by the UNDP/ World Bank/WHO Special Programme for Research and Training in Tropical Diseases;the National Science and Technology Development Agency of Thailand(Career Development Award);the Thailand Research Fund(Basic Research);the Office of Higher Education Commission (University Staff Development Consortium),Thailand
Malaria is a major cause of morbidity and mortality in the developing world.This situation is mainly due to emergence of resistance to most antimalarial drugs currently available. Artemisinin-based combination treatme...
关键词：MALARIA PLASMODIUM FALCIPARUM CHEMOTHERAPY ARTEMISININ Drug RESISTANCE 
Subcloning,sequencing and expressing of conserved blocks of P190 gene of Plasmodium falciparum FCC1/HN strain
《Journal of Medical Colleges of PLA(China)》1993年第3期246-253,共8页杨树桐 潘卫庆 邓海琳 陆德如 
This study was supported by UNDP/WORLD BANK/WHO Special Programme for Research and Training in Tropical Diseases(TDR),ID No.910265
190-kilodalton glycoprotein (P190) of Plasmodium falciparum,precursor of themajor surface protein of merozoites,is considered a promising candidate for blood stage malarialvaccine.Six primers were designed according t...
关键词：PLASMODIUM FALCIPARUM MEROZOITE surface ANTIGEN l CONSERVED sequences vaccine 
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