supported by the Natural Science Foundation of Zhejiang Province,China(Grant No.:LY24C190001);the General Scientific Research Project of Education of Zhejiang Province,China(Grant Nos.:Y202352559 and Y202147351);the Starting Research Fund of Ningbo University,China(Grant Nos.:421912073 and 422204123);the Student Research and Innovation Program of Ningbo University,China(Grant Nos.:2023SRIP1810 and 2023SRIP1804).
Jumonji domain-containing protein D3(JMJD3)is a 2-oxoglutarate-dependent dioxygenase that specifically removes transcriptional repression marks di-and tri-methylated groups from lysine 27 on histone 3(H3K27me2/3).The ...
2018 Henan Medical Science and Technology Research Plan Project,China,No.SBGJ2018019.
BACKGROUND Osteoporosis is a common metabolic bone disorder induced by an imbalance between osteoclastic activity and osteogenic activity.During osteoporosis,bone mesenchymal stem cells(BMSCs)exhibit an increased abil...