BIOCHIP

作品数:25被引量:42H指数:3
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相关作者:孙丽慧郭建林姜建湖陈建明李倩更多>>
相关机构:清华大学浙江大学舟山海洋研究中心浙江省淡水水产研究所国立高雄应用科技大学更多>>
相关期刊:《Chinese Journal of Cancer Research》《Microsystems & Nanoengineering》《Science China(Technological Sciences)》《Optoelectronics Letters》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划上海市自然科学基金国家高技术研究发展计划更多>>
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Microfluidic Barcode Biochips for High-Throughput Real-Time Biomolecule and Single-Cell Screening
《Engineering》2025年第3期130-146,共17页Jiaoyan Qiu Yanbo Liang Chao Wang Yang Yu Yu Zhang Hong Liu Lin Han 
supported by the National Key Research and Development Plan of China(2023YFB3210400);the Natural Science Innovation Group Foundation of China(T2321004);the National Natural Science Foundation of China(62174101);Shandong University Integrated Research and Cultivation Project(2022JC001);Key Research and Development Plan of Shandong Province(Major Science and Technology Innovation Project;2022CXGC020501).
The real-time screening of biomolecules and single cells in biochips is extremely important for disease prediction and diagnosis,cellular analysis,and life science research.Barcode biochip technology,which is integrat...
关键词:HIGH-THROUGHPUT Microfluidic barcode biochip Single-cell analysis Biomolecules 
Detection of Environmental Toxins in Mixed Matrices of Tap Water, Soil, Food Waste, Serum and Milk Using Hememics Biosensor
《Journal of Sensor Technology》2023年第4期59-68,共10页Srivatsa Aithal Sujasha Gupta Khanh Duong Ankit Kumar Nathan Ho Dongdong Liu John Warden David Huy Ho 
Exposure to toxins can lead to a wide range of adverse health effects, including respiratory problems, neurological disorders, cancer, and reproductive issues. Toxins can come from various sources, such as industrial ...
关键词:Portable Biosensor Graphene Based Biochip HemChip™ Rapid Detection Field Use NETWORKING 
A deformability-based biochip for precise label-free stratification of metastatic subtypes using deep learning
《Microsystems & Nanoengineering》2023年第5期161-176,共16页Haojun Hua Shangjie Zou Zhiqiang Ma Wang Guo Ching Yin Fong Bee Luan Khoo 
supported in part by InnoHK Project on[Project 1-5 Multimodal spectroscopy(MMS)&biosensor platforms for monitoring CVDs]at Hong Kong Centre for Cerebro-cardiovascular Health Engineering(COCHE),in part by City University of Hong Kong(7020002,7005464,7005208,9667220);which is funded by the Research Grants Council(RGC),in part by Pneumoconiosis Compensation Fund Board(9211276);in part by Research Grants Council of the Hong Kong Special Administrative Region,China(CityU 21200921).
Cellular deformability is a promising biomarker for evaluating the physiological state of cells in medical applications.Microfluidics has emerged as a powerful technique for measuring cellular deformability.However,ex...
关键词:DEFORMABILITY METASTATIC PRECISE 
A deep-reinforcement learning approach for optimizing homogeneous droplet routing in digital microfluidic biochips
《Nanotechnology and Precision Engineering》2023年第2期1-12,共12页Basudev Saha Bidyut Das Mukta Majumder 
Over the past two decades,digital microfluidic biochips have been in much demand for safety-critical and biomedical applications and increasingly important in point-of-care analysis,drug discovery,and immunoassays,amo...
关键词:Digital microfluidics BIOCHIP Droplet routing Fluidic constraints Deep learning Reinforcement learning 
循环水养殖系统中3种生物填料的挂膜、微生物群落组成及对大口黑鲈生长的影响被引量:1
《河南农业科学》2023年第3期143-152,共10页李倩 孙丽慧 郭建林 郑刚 姜建湖 陈建明 高令梅 
浙江省重点研发计划项目(2021C02024);湖州市乡村振兴专项(2019ZD2028)。
为探索大口黑鲈循环水养殖系统中适宜的水处理生物填料,以方形海绵、Mutag Biochip 30和流化球生物填料为研究对象,以初始体质量为(20.46±0.46)g的大口黑鲈为养殖对象,分析生物填料的挂膜时间及微生物群落组成,并评估大口黑鲈的生长情...
关键词:大口黑鲈 循环水养殖 生物填料 方形海绵 Mutag Biochip 30 流化球 
All-printed nanophotonic biochip for point-of-care testing of biomarkers被引量:1
《Science Bulletin》2022年第12期1191-1193,共3页Jimei Chi Dongdong Wu Meng Su Yanlin Song 
supported by the Beijing Nova Program from Beijing Municipal Science&Technology Commission(Z201100006820037,Z211100002121001);the National Key Research and Development Program of China(2018YFA0208501);the National Natural Science Foundation of China(22075296,91963212,and 51961145102);the Youth Innovation Promotion Association of CAS(2020032);Beijing National Laboratory for Molecular Sciences(CXXM-202005)。
Under the global pandemic of COVID-19,point-of-care testing(POCT)strategy as a fast,simple,and low-cost biological detection method has drawn much attention for achieving accurate on-site testing[1].
关键词:POCT 生物标志物 即时检测 
A reversible microarray immobilization strategy based on thiol-quinone reaction
《Chinese Chemical Letters》2022年第1期213-216,共4页Ling Feng Ping Wang Yi Feng Jie Zhang Qingxin Chen Yusheng Xie Jingdong Luo Jiang Xia Shao Q.Yao Hongyan Sun 
the financial support from the Research Grants Council of Hong Kong(Nos.11102719,11304118 and 14306317);Shenzhen Basic Research Project(No.JCYJ20160601173218804);National Natural Science Foundation of China(No.21778044);the Shandong University of Technology Ph.D.Startup Foundation(No.420033)。
Microarray technology has been widely applied in biomedical research.The key to microarray study is to develop efficient immobilization method.In this study,we designed a new reversible microarray immobilization metho...
关键词:Reversible Microarray BIOCHIP Thiol-quinone reaction Peptides Thiol-proteins 
Low-Cost and Scalable Platform with Multiplexed Microwell Array Biochip for Rapid Diagnosis of COVID-19被引量:3
《Research》2021年第1期94-102,共9页Yang Wang Kaiju Li Gaolian Xu Chuan Chen Guiqin Song Zaizai Dong Long Lin Yu Wang Zhiyong Xu Mingxia Yu Xinge Yu Binwu Ying Yubo Fan Lingqian Chang Jia Geng 
supported by the Special Research Funding on COVID19 from Sichuan Province of China(Grant No.2020YFS0004);Science and Technology Department,Ministry of Education of the People’s Republic of China,the NSFC(No.32071407 and No.62003023);the 111 Project(No.B13003);Innovation Research Plan from the Shanghai Municipal Education Commission(ZXWF082101/056);Exploratory Project of Natural Science Foundation of Shanghai(19ZR1476000);Beijing Advanced Innovation Center for Biomedical Engineering at Beihang University。
Sensitive detection of SARS-CoV-2 is of great importance for inhibiting the current pandemic of COVID-19.Here,we report a simple yet efficient platform integrating a portable and low-cost custom-made detector and a no...
关键词:instrument diagnosis SPECIFICITY 
A 3D biophysical model for cancer spheroid cell-enhanced invasion in collagen-oriented fiber microenvironment
《Chinese Physics B》2020年第9期581-588,共8页Miaomiao Hai Yanping Liu Ling Xiong Guoqiang Li Gao Wang Hongfei Zhang Jianwei Shuai Guo Chen Liyu Liu 
Project supported by the National Natural Science Foundation of China(Grant Nos.11974066 and 11674043);the Fundamental Research Funds for the Central Universities,China(Grant No.2019CDYGYB007);the Natural Science Foundation of Chongqing,China(Grant No.cstc2019jcyj-msxmX0477).
The process of in situ tumors developing into malignant tumors and exhibiting invasive behavior is extremely complicated.From a biophysical point of view,it is a phase change process affected by many factors,including...
关键词:3D biochip SPHEROIDS MDA-MB-231 cells oriented collagen fibers cancer cell invasion 
A multifunctional integrated simultaneously online screening microfluidic biochip for the examination of “efficacy-toxicity” and compatibility of medicine被引量:2
《Chinese Chemical Letters》2019年第2期403-405,共3页Hechen Wang Tianjiao Li Yongrui Bao Shuai Wang Xiansheng Meng 
A multifunctional integrated microfluidic biochip device was engineered to estimate the activity-toxicity and composition principle of medicine in a cell model in vitro. This biochip could be used for disease cells an...
关键词:MULTIFUNCTIONAL integrated microfluidic BIOCHIP Cirsium setosum(Wild.) Efficacy-toxicity of MEDICINES Compatibility of MEDICINES Simultaneously online SCREENING 
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