N-MYC

作品数:123被引量:273H指数:8
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相关领域:医药卫生生物学更多>>
相关作者:张锦华宫丽平汤静燕王芳张健更多>>
相关机构:中国医科大学上海交通大学首都医科大学安徽医科大学更多>>
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相关基金:国家自然科学基金广东省自然科学基金云南省自然科学基金陕西省自然科学基金更多>>
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The delivery of N-myc downstream-regulated gene 2(NDRG2)self-amplifying mRNA via modified lipid nanoparticles as a potential treatment for drug-resistant and metastatic cancers
《Medical Review》2024年第3期235-238,共4页Sandra E.Reznik Amit K.Tiwari Vivek Chavda Charles R.Ashby Jr. 
The protein,N-myc downstream-regulated gene 2(NDRG2),a tumor suppressor,is significantly decreased or absent in many types of cancer.There is a significant negative correlation between the levels of NDRG2 and the deve...
关键词:N-myc downstream-regulated gene 2(NDRG2) cancer self-amplifying mRNA nanoparticle 
NDRG1 promotes endothelial dysfunction and hypoxia-induced pulmonary hypertension by targeting TAF15
《Precision Clinical Medicine》2023年第4期200-212,共13页Chengwei Li Junzhu Lv Gulinuer Wumaier Yu Zhao Liang Dong Yuzhen Zeng Ning Zhu Xiujuan Zhang Jing Wang Jingwen Xia Shengqing Li 
supported by the National Natural Science Foundation of China(Grants No.81970048,82270058);starting fund for scientific research of Huashan Hospital Fudan University(Grant No.2017QD078).
Background:Pulmonary hypertension(PH)represents a threatening pathophysiologic state that can be induced by chronic hypoxia and is characterized by extensive vascular remodeling.However,the mechanism underlying hypoxi...
关键词:N-myc downstream regulated gene-1 TATA-box binding protein associated factor 15 hypoxia-induced pulmonary hyper-tension endothelial dysfunction vascular remodeling 
N-myc downstream regulated gene 1 inhibition of tumor progression in Caco2 cells被引量:2
《World Journal of Gastrointestinal Oncology》2022年第12期2313-2328,共16页Yi-Xiao He Hong Shen Yu-Zhu Ji Hai-Rong Hua Yu Zhu Xiang-Fei Zeng Fang Wang Kai-Xin Wang 
the National Natural Science Foundation of China,No.81260361;Incubation Project of Mianyang Central Hospital,No.2020FH05.
BACKGROUND Invasion and migration are the irreversible stages of colorectal cancer(CRC).The key is to find a sensitive,reliable molecular marker that can predict the migration of CRC at an early stage.N-myc downstream...
关键词:N-myc downstream regulated gene 1 Caco2 Colorectal cancer Tumor progression CRISPR/Cas9 Lentivirus infection 
Prognostic and biological role of the N-Myc downstream-regulated gene family in hepatocellular carcinoma被引量:2
《World Journal of Clinical Cases》2022年第7期2072-2086,共15页Xin Yin Hao Yu Xing-Kang He Sen-Xiang Yan 
BACKGROUND The N-Myc downstream-regulated gene(NDRG)family is comprised of four members(NDRG1-4)involved in various important biological processes.However,there is no systematic evaluation of the prognostic of the NDR...
关键词:N-Myc downstream-regulated gene family BIOINFORMATICS Hepatocellular carcinoma PROGNOSIS Tumor-infiltrating immune cells 
Expression of N-myc downstream regulatory gene 4(NDRG4)in glioma and its relationship with glioma prognosis
《Journal of Translational Neuroscience》2021年第2期8-11,共4页Zhumei Niu Yinyan Bai Xiaopeng Li Xiaolong Jia 
Objective:the N-myc downstream regulatory gene 4(NDRG4)is involved in cell growth,cell proliferation,cell survival and tumor invasion.In this paper,the role of NDRG4 in glioma was explored.Method:the expression of NDR...
关键词:N-myc downstream regulatory gene 4(NDRG4) GLIOMA MRNA 
Anti-fibrotic Effects and Mechanism of Shengmai Injection(生脉注射液)on Human Hepatic Stellate Cells LX-2被引量:6
《Chinese Journal of Integrative Medicine》2019年第3期197-202,共6页ZHANG Yi MA Li-tian LI Jie QIAO Yu LIU Jun-ye WANG Jin REN Qin-you HU Jin-tao ZHENG Jin 
Supported by the National Natural Sciences Foundation of China(No.81072973)
Objective: To investigate the effects of Shengmai Injection(生脉注射液, SMI) on the proliferation, apoptosis and N-myc downstream-regulated gene 2(NDRG2, a tumour suppressor gene) expression in varying densities of hu...
关键词:SHENGMAI injection liver FIBROSIS N-MYC downstream-regulated gene 2 LX-2 cell proliferation apoptosis Chinese medicine 
N-myc downstream-regulated gene 2 promotes proliferation of HO-8910 ovarian cancer cells被引量:2
《Oncology and Translational Medicine》2018年第4期171-175,共5页Fenhong Kang Yaping Luo Yanlong Wang 
Objective To investigate N-myc downstream-regulated gene 2(NDRG2) expression in ovarian cancer cells and its potential usefulness as a diagnostic marker and/or target for therapeutic intervention.Methods Human NDRG2 L...
关键词:N-myc downstream-regulated gene 2 (NDRG2) ovarian cancer HO-8910 cell MTT CISPLATIN 
Lipoxin A4 Ameliorates Lipopolysaccharide-lnduced A549 Cell Injury through Upregulation of N-myc Downstream-Regulated Gene-1被引量:5
《Chinese Medical Journal》2018年第11期1342-1348,共7页Jun-Zhi Zhang Zhan-Li Liu Yao-Xian Zhang Hai-Jiu Lin Zhong-Jun Zhang 
Background: Lipoxin A4 (LXA4) can alleviate lipopolysaccharide (LPS)-induced acute lung injury (ALl) and acute respiratory distress syndrome through promoting epithelial sodium channel (ENaC) expression in lu...
关键词:Acute Lung Injury Epithelial Sodium Channel LIPOPOLYSACCHARIDE Lipoxin A4 N-myc Downstream-Regulated Gene-1 
Correlation of LSD1 and NDRG1 gene expression in ovarian cancer tissue with cancer cell migration and invasion
《Journal of Hainan Medical University》2018年第4期5-8,共4页Yu Bai Ming-Jie Li Li-Ping Fan Mai-Juan Zhao Chang-Min Bai 
Objective: To study the correlation of LSD1 and NDRG1 gene expression in ovarian cancer tissue with cancer cell migration and invasion. Methods: Patients with ovarian cancer who underwent surgical resection in Fufeng ...
关键词:OVARIAN cancer Lysine-specific DEMETHYLASE 1 N-MYC DOWNSTREAM regulated 1 Migration Invasion 
Anti-fibrotic Effects of Salvia miltiorrhiza and Ligustrazine Injection on LX-2 Cells Involved with Increased N-myc Downstream-Regulated Gene 2 Expression被引量:13
《Chinese Journal of Integrative Medicine》2017年第12期923-928,共6页zheng jin ma li-tian ren qin-you hu yue bai yang bian huan zhang yi zhou yong-chun yang ming-hui 
Supported by the National Natural Science Foundation of China(No.81272490 and 81100764)
Objective: To investigate the effects of Salvia miltiorrhiza and Ligustrazine Injection(SML) on proliferation and apoptosis of human hepatic stellate cell LX-2 and the expression of N-myc downstreamregulated gene 2...
关键词:Salvia miltiorrhiza and Ligustrazine Injection N-myc downstream-regulated gene 2 hepatic stellate cell proliferation apoptosis 
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