supported by the National Natural Science Foundation of China(31071251 and 81471255);the National Basic Research Development Program of China(2014CB542202);the Basic Research Program of the Department of Education,Jiangsu Province,China(14KJA310004);a Natural Science Research Project of Nantong Science and Technology Bureau,Jiangsu Province,China(HS2013014);the Natural Science Research Project of Nantong University,Jiangsu Province,China(12Z045,13Z008)
Myelination by oligodendrocytes in the central nervous system requires coordinated exocytosis and endocytosis of the major myelin protein, proteolipid protein (PLP). Here, we demonstrated that a small GTPase, Rab27b...
In this study, we investigated the clinical relevance of anti-myelin antibodies in patients with neuromyelitis optica (NMO);titers of antibodies against myelin oligodendrocyte glycoproteins, proteolipid proteins and m...
To detect the function of proteolipid protein (PLP) peptide (residues 56-70) sp ecific CD 4 + T cells in experimental allergic encephalomyelitis (EAE) in Bioz zi AB/H mice (H 2A g7 ) Methods Biozzi AB/H mice were immu...
The participation of immune mechanisms in the pathogenesis of dementia of Alzheimer type (AD) has been suggested. We examined T cell responses to myelin basic protein (MBP) and myelin prot...