supported by the National Key Research and Development Project(No.2019YFC1005203);National Natural Science Foundation of China(No.81771608&82120108011);Major Project of Shanghai Municipal Education Commission’s Scientific Research and Innovation Plan(No.2021-01-07-00-07-E00144);Outstanding Academic Leaders Program of Shanghai Municipal Science and Technology Commission(No.18XD1405100);“Shuguang Program”supported by Shanghai Municipal Education Commission(No.17SG36);the Program for Professor of Special Appointment(Eastern Scholar)at Shanghai Institutions of Higher Learning。